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The map label for this gene is arsB [H]

Identifier: 220916196

GI number: 220916196

Start: 1216198

End: 1217343

Strand: Reverse

Name: arsB [H]

Synonym: A2cp1_1085

Alternate gene names: 220916196

Gene position: 1217343-1216198 (Counterclockwise)

Preceding gene: 220916197

Following gene: 220916195

Centisome position: 24.2

GC content: 69.37

Gene sequence:

>1146_bases
ATGCCTGACGCCCTCTCCTCCGCCCCGGCGCGCGCGAGCGTCGCCCGCCGCCTCTCCTTCCTCGACCGCTTCCTGACCGT
CTGGATCTTCCTTGCCATGGGCGCGGGCATCCTGCTCGGCTGGGCGGCCCCGGGGATCGTCCCCGCGCTCGACCGCCTGA
GCGTGGGCACCACCTCGATCCCGATCGCGGTGGGGCTCATCCTGATGATGTACCCGCCGCTCGCGAAGGTCCGCTACGAG
GAGCTGCCGCGCGTCTTCCGGAACGGCAAGGTCCTGGCGCTCTCCCTCGTGCAGAACTGGATCGTCGGGCCGGTGCTCAT
GTTCGCGCTGGCGGTGATCTTCCTGCGCGACCGTCCCGAGTACATGGTCGGCCTGATCCTCATCGGCCTGGCGCGCTGCA
TCGCCATGGTGATCGTGTGGAACGACCTCGCGAAGGGGGACACCGAGTACTGCGCCGGCCTGGTCGCGTTCAACTCGATC
TTCCAGGTGCTGTTCTTCTCGGTCTACGCGTGGGTCTTCATCACGGTGCTGCCGGGGTGGCTCGGGCTGCGCGGCGCCGA
GGTCCACATCACCATCGGCGAGATCGCCCGGAGCGTCTTCGTCTACCTCGGCGTCCCGTTCCTGGCCGGCATGGCGAGCC
GGTTCGGCCTGCGGGCGCTCAAGGGCGAGGCGTGGTACCGCCGGGTGTTCATCCCGCGGATCTCCCCGATCACCCTCGTC
GCCCTGCTCTTCACCATCGTGGTGATGTTCTCGCTGAAGGGCGAGACCATCGTGCAGGTGCCCTTCGACGTGGTCCGGAT
CGCGATCCCGCTCCTCGTCTACTTCCTGCTCATGTTCTTCGTCTCTTTCTGGATGAGCCGGAAGGTCGGCGCCACCTATG
GCCAGACGGCCACGCTCTCGTTCACCGCGGCCTCCAACAACTTCGAGCTGGCCATCGCGGTGGCGGTGGCGACGTTCGGG
ATGGCGCACGGCGCGGCGTTCGCCGCGGTGATCGGCCCGCTCGTCGAGGTGCCGGTCCTCATCGGCCTCGTGAACGTGGC
GCTCCGCCTGCGCGACCGCTGGTTCCCCGGCGAGGCGGGCGAGATCGCGCGGGTGGCGAACTGCGCCGTGGCGGTGGACG
GCCCGGCGGCCGGGAGGGGCCGGTGA

Upstream 100 bases:

>100_bases
TCGTCCGCGGCGAGATCGACGGGCCGCGCGTCTGCTACTGCGTGGAGCCCCGCACCCTCCGCCGCCTGAAGGCGCTCGTC
GGAAGCCTCTAGGAGCCCCC

Downstream 100 bases:

>100_bases
GCGCGGACGCGGCCTGGCAGGAGGAGGCGGCGCGGCTCCGGGCGGCGCCGCCGCGCCACCTGCTGTTCCTCTGCGTCGCG
AACTCGGCGCGCAGCCAGAT

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MPDALSSAPARASVARRLSFLDRFLTVWIFLAMGAGILLGWAAPGIVPALDRLSVGTTSIPIAVGLILMMYPPLAKVRYE
ELPRVFRNGKVLALSLVQNWIVGPVLMFALAVIFLRDRPEYMVGLILIGLARCIAMVIVWNDLAKGDTEYCAGLVAFNSI
FQVLFFSVYAWVFITVLPGWLGLRGAEVHITIGEIARSVFVYLGVPFLAGMASRFGLRALKGEAWYRRVFIPRISPITLV
ALLFTIVVMFSLKGETIVQVPFDVVRIAIPLLVYFLLMFFVSFWMSRKVGATYGQTATLSFTAASNNFELAIAVAVATFG
MAHGAAFAAVIGPLVEVPVLIGLVNVALRLRDRWFPGEAGEIARVANCAVAVDGPAAGRGR

Sequences:

>Translated_381_residues
MPDALSSAPARASVARRLSFLDRFLTVWIFLAMGAGILLGWAAPGIVPALDRLSVGTTSIPIAVGLILMMYPPLAKVRYE
ELPRVFRNGKVLALSLVQNWIVGPVLMFALAVIFLRDRPEYMVGLILIGLARCIAMVIVWNDLAKGDTEYCAGLVAFNSI
FQVLFFSVYAWVFITVLPGWLGLRGAEVHITIGEIARSVFVYLGVPFLAGMASRFGLRALKGEAWYRRVFIPRISPITLV
ALLFTIVVMFSLKGETIVQVPFDVVRIAIPLLVYFLLMFFVSFWMSRKVGATYGQTATLSFTAASNNFELAIAVAVATFG
MAHGAAFAAVIGPLVEVPVLIGLVNVALRLRDRWFPGEAGEIARVANCAVAVDGPAAGRGR
>Mature_380_residues
PDALSSAPARASVARRLSFLDRFLTVWIFLAMGAGILLGWAAPGIVPALDRLSVGTTSIPIAVGLILMMYPPLAKVRYEE
LPRVFRNGKVLALSLVQNWIVGPVLMFALAVIFLRDRPEYMVGLILIGLARCIAMVIVWNDLAKGDTEYCAGLVAFNSIF
QVLFFSVYAWVFITVLPGWLGLRGAEVHITIGEIARSVFVYLGVPFLAGMASRFGLRALKGEAWYRRVFIPRISPITLVA
LLFTIVVMFSLKGETIVQVPFDVVRIAIPLLVYFLLMFFVSFWMSRKVGATYGQTATLSFTAASNNFELAIAVAVATFGM
AHGAAFAAVIGPLVEVPVLIGLVNVALRLRDRWFPGEAGEIARVANCAVAVDGPAAGRGR

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=324, Percent_Identity=34.5679012345679, Blast_Score=178, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 41400; Mature: 41269

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDALSSAPARASVARRLSFLDRFLTVWIFLAMGAGILLGWAAPGIVPALDRLSVGTTSI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHH
PIAVGLILMMYPPLAKVRYEELPRVFRNGKVLALSLVQNWIVGPVLMFALAVIFLRDRPE
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHH
YMVGLILIGLARCIAMVIVWNDLAKGDTEYCAGLVAFNSIFQVLFFSVYAWVFITVLPGW
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLRGAEVHITIGEIARSVFVYLGVPFLAGMASRFGLRALKGEAWYRRVFIPRISPITLV
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCHHHHH
ALLFTIVVMFSLKGETIVQVPFDVVRIAIPLLVYFLLMFFVSFWMSRKVGATYGQTATLS
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
FTAASNNFELAIAVAVATFGMAHGAAFAAVIGPLVEVPVLIGLVNVALRLRDRWFPGEAG
EEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EIARVANCAVAVDGPAAGRGR
CHHHHHHCEEEECCCCCCCCC
>Mature Secondary Structure 
PDALSSAPARASVARRLSFLDRFLTVWIFLAMGAGILLGWAAPGIVPALDRLSVGTTSI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHH
PIAVGLILMMYPPLAKVRYEELPRVFRNGKVLALSLVQNWIVGPVLMFALAVIFLRDRPE
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHH
YMVGLILIGLARCIAMVIVWNDLAKGDTEYCAGLVAFNSIFQVLFFSVYAWVFITVLPGW
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLRGAEVHITIGEIARSVFVYLGVPFLAGMASRFGLRALKGEAWYRRVFIPRISPITLV
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCHHHHH
ALLFTIVVMFSLKGETIVQVPFDVVRIAIPLLVYFLLMFFVSFWMSRKVGATYGQTATLS
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
FTAASNNFELAIAVAVATFGMAHGAAFAAVIGPLVEVPVLIGLVNVALRLRDRWFPGEAG
EEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EIARVANCAVAVDGPAAGRGR
CHHHHHHCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]