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The map label for this gene is arsC [H]

Identifier: 220916195

GI number: 220916195

Start: 1215302

End: 1216201

Strand: Reverse

Name: arsC [H]

Synonym: A2cp1_1084

Alternate gene names: 220916195

Gene position: 1216201-1215302 (Counterclockwise)

Preceding gene: 220916196

Following gene: 220916194

Centisome position: 24.18

GC content: 76.11

Gene sequence:

>900_bases
GTGAGCGCGGACGCGGCCTGGCAGGAGGAGGCGGCGCGGCTCCGGGCGGCGCCGCCGCGCCACCTGCTGTTCCTCTGCGT
CGCGAACTCGGCGCGCAGCCAGATGGCCGAGGGCATCGCGCGCGCGCTCGCGCCCGCGTCCACCCGGATCTCGTCCGCGG
GATCCCGCCCGACGCAGGTGAACCCGCTCGCCGTCGCGGCGCTCGCCGAGATCGGGATCGAGATCTCCGGCCAGCGCTCG
AAGGGGCTGCAGGAGATCGCGCCCGACGTGGACGCGGTGATCACGCTGTGCCAGGAGGAGGTCTGCCCCGTCTGGCTGGG
CAAGGCGATGCGGCTGCACTGGGGCCTGCCTGATCCGGCGGCGCAGGCGGGCGACGAACCTGCACGGCTGGAGGCCTTCC
GCCGGGTCCGGGACGAGCTTCGCACCCGGCTCGCGGCCGTGTTCCGCCAGCCGGACGGCGACGCGATCCGGTACGGGCCG
GCGACGCCGGAGGAGCTCGGCGCCGTTCGCGCGCTGCTCGAGCGGCTGCACCTCCCGGCGGCGGACGTCGGGGCGCCGCA
CCAGACGTTCCTGGTGGCGCGCTCCGGCGCCGACGTGGTGGGCTGCGTGGCGCTGGAGCGGTACGGCGAGGACGCGCTGC
TCCGCTCGCTCGGGGTCGTCCCGCGCCTGCAGGGTTCAGGCGTCGGCAAGGCGCTCCATGCCGAGGCGATCGCCGAGGCC
GAGCGGCAGGGCGTGCGCGCGCTGTACCTGCTCACGACGACGGCGGCGCGGTTCTTCGCGCGCGCGGGCTTCTCGAGGAT
CGACCGCGCGAGCGTCCCGGCGGCGCTGGCCGCGAGCACCGAGTTCCGATCGCTCTGCCCGGCCGCCGCGGTCTGCATGG
TGAAGCACCTCCCCCGCTAG

Upstream 100 bases:

>100_bases
TCCGCCTGCGCGACCGCTGGTTCCCCGGCGAGGCGGGCGAGATCGCGCGGGTGGCGAACTGCGCCGTGGCGGTGGACGGC
CCGGCGGCCGGGAGGGGCCG

Downstream 100 bases:

>100_bases
CCGGGACGGAGGGCGGCCGGGCCGGGCGCCCACGGCGAAGCTGGGTCGCCCCGTCCGCCATGTCGCGCGGGTGACATCCG
GCACGCAGGGTCTCGCGATG

Product: Protein-tyrosine phosphatase, low molecular weight

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSADAAWQEEAARLRAAPPRHLLFLCVANSARSQMAEGIARALAPASTRISSAGSRPTQVNPLAVAALAEIGIEISGQRS
KGLQEIAPDVDAVITLCQEEVCPVWLGKAMRLHWGLPDPAAQAGDEPARLEAFRRVRDELRTRLAAVFRQPDGDAIRYGP
ATPEELGAVRALLERLHLPAADVGAPHQTFLVARSGADVVGCVALERYGEDALLRSLGVVPRLQGSGVGKALHAEAIAEA
ERQGVRALYLLTTTAARFFARAGFSRIDRASVPAALAASTEFRSLCPAAAVCMVKHLPR

Sequences:

>Translated_299_residues
MSADAAWQEEAARLRAAPPRHLLFLCVANSARSQMAEGIARALAPASTRISSAGSRPTQVNPLAVAALAEIGIEISGQRS
KGLQEIAPDVDAVITLCQEEVCPVWLGKAMRLHWGLPDPAAQAGDEPARLEAFRRVRDELRTRLAAVFRQPDGDAIRYGP
ATPEELGAVRALLERLHLPAADVGAPHQTFLVARSGADVVGCVALERYGEDALLRSLGVVPRLQGSGVGKALHAEAIAEA
ERQGVRALYLLTTTAARFFARAGFSRIDRASVPAALAASTEFRSLCPAAAVCMVKHLPR
>Mature_298_residues
SADAAWQEEAARLRAAPPRHLLFLCVANSARSQMAEGIARALAPASTRISSAGSRPTQVNPLAVAALAEIGIEISGQRSK
GLQEIAPDVDAVITLCQEEVCPVWLGKAMRLHWGLPDPAAQAGDEPARLEAFRRVRDELRTRLAAVFRQPDGDAIRYGPA
TPEELGAVRALLERLHLPAADVGAPHQTFLVARSGADVVGCVALERYGEDALLRSLGVVPRLQGSGVGKALHAEAIAEAE
RQGVRALYLLTTTAARFFARAGFSRIDRASVPAALAASTEFRSLCPAAAVCMVKHLPR

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 31783; Mature: 31652

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADAAWQEEAARLRAAPPRHLLFLCVANSARSQMAEGIARALAPASTRISSAGSRPTQV
CCCCHHHHHHHHHHCCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NPLAVAALAEIGIEISGQRSKGLQEIAPDVDAVITLCQEEVCPVWLGKAMRLHWGLPDPA
CHHHHHHHHHHCCEECCCHHCCHHHHCCCHHHHHHHHHHHCCHHHHCCHHHEECCCCCHH
AQAGDEPARLEAFRRVRDELRTRLAAVFRQPDGDAIRYGPATPEELGAVRALLERLHLPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCC
ADVGAPHQTFLVARSGADVVGCVALERYGEDALLRSLGVVPRLQGSGVGKALHAEAIAEA
CCCCCCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ERQGVRALYLLTTTAARFFARAGFSRIDRASVPAALAASTEFRSLCPAAAVCMVKHLPR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SADAAWQEEAARLRAAPPRHLLFLCVANSARSQMAEGIARALAPASTRISSAGSRPTQV
CCCHHHHHHHHHHCCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NPLAVAALAEIGIEISGQRSKGLQEIAPDVDAVITLCQEEVCPVWLGKAMRLHWGLPDPA
CHHHHHHHHHHCCEECCCHHCCHHHHCCCHHHHHHHHHHHCCHHHHCCHHHEECCCCCHH
AQAGDEPARLEAFRRVRDELRTRLAAVFRQPDGDAIRYGPATPEELGAVRALLERLHLPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCC
ADVGAPHQTFLVARSGADVVGCVALERYGEDALLRSLGVVPRLQGSGVGKALHAEAIAEA
CCCCCCCCEEEEECCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ERQGVRALYLLTTTAARFFARAGFSRIDRASVPAALAASTEFRSLCPAAAVCMVKHLPR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]