Click here to switch to the map view.

The map label for this gene is gpt [H]

Identifier: 220916180

GI number: 220916180

Start: 1196497

End: 1197063

Strand: Reverse

Name: gpt [H]

Synonym: A2cp1_1067

Alternate gene names: 220916180

Gene position: 1197063-1196497 (Counterclockwise)

Preceding gene: 220916181

Following gene: 220916179

Centisome position: 23.8

GC content: 71.25

Gene sequence:

>567_bases
ATGGCGGCAGACGCGACGAAGGGCCCTCCCGGCGGCGGGGAGGGTGAGGTCCATGCTGGCTCGGGGCCCGGTCCGTACCA
GGACGAGATCGTCATCTCCTGGCCCGAGCTGCACCGCGACGCTCGCTACCTGTCGCGCGTGCTCCACGAGCTCGGCGACT
GGAAGGGCATCATCGCCATCACGCGCGGCGGCCTCGTGCCGGCGGCGCTGGTGGCGCGCGAGCTCGACATCCGCCTCATC
GACACCGTCTGCGTGGTCAGCTACGGCGCCGCCGAGACGGGCGGCGCGGAGGCGAAGCAGGGCGCGCTGCAGTGGCTGAA
GACGGTCCCGGGGGACGGCGAGGGCTGGCTGCTCATCGACGACCTGGTGGACACGGGCCGGACCGCCGCCGCGGTGCGGG
AGAAGCTGCCGAAGGCACACTTCGCCACGCTGTACGCGAAGCCGCTCGGCCGCCCGGTGGTGGACACGTTCGTGAAGGAG
TTCCGCCAGGAGAAGTGGATCTACTTCCCGTGGGACATCGACTACCGGTTCGTCACGCCGATCCGCCAGCGGGGCGCGAA
GGACTAG

Upstream 100 bases:

>100_bases
GAGTACGAGCCCGCGCCGTAGCGCCGCCCCGAAATCGCCCGTAAATCCGGGGAGGTGAATTCCCCCTCCCCTGCGTCAGC
CCCTTCCAGTACAAGGTGCC

Downstream 100 bases:

>100_bases
GGGCCCGACGTGAGCGTTCCGCGCCTCGAGCTGAGGCACGTCACCAAGCGCTACGGGGACGTCGTCGCGAACGACGACGT
GGCGCTCTCCGTCGCGCCGG

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAADATKGPPGGGEGEVHAGSGPGPYQDEIVISWPELHRDARYLSRVLHELGDWKGIIAITRGGLVPAALVARELDIRLI
DTVCVVSYGAAETGGAEAKQGALQWLKTVPGDGEGWLLIDDLVDTGRTAAAVREKLPKAHFATLYAKPLGRPVVDTFVKE
FRQEKWIYFPWDIDYRFVTPIRQRGAKD

Sequences:

>Translated_188_residues
MAADATKGPPGGGEGEVHAGSGPGPYQDEIVISWPELHRDARYLSRVLHELGDWKGIIAITRGGLVPAALVARELDIRLI
DTVCVVSYGAAETGGAEAKQGALQWLKTVPGDGEGWLLIDDLVDTGRTAAAVREKLPKAHFATLYAKPLGRPVVDTFVKE
FRQEKWIYFPWDIDYRFVTPIRQRGAKD
>Mature_187_residues
AADATKGPPGGGEGEVHAGSGPGPYQDEIVISWPELHRDARYLSRVLHELGDWKGIIAITRGGLVPAALVARELDIRLID
TVCVVSYGAAETGGAEAKQGALQWLKTVPGDGEGWLLIDDLVDTGRTAAAVREKLPKAHFATLYAKPLGRPVVDTFVKEF
RQEKWIYFPWDIDYRFVTPIRQRGAKD

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=158, Percent_Identity=50.6329113924051, Blast_Score=152, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20562; Mature: 20430

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADATKGPPGGGEGEVHAGSGPGPYQDEIVISWPELHRDARYLSRVLHELGDWKGIIAI
CCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCEEEEE
TRGGLVPAALVARELDIRLIDTVCVVSYGAAETGGAEAKQGALQWLKTVPGDGEGWLLID
ECCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEH
DLVDTGRTAAAVREKLPKAHFATLYAKPLGRPVVDTFVKEFRQEKWIYFPWDIDYRFVTP
HHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCEEECH
IRQRGAKD
HHHCCCCC
>Mature Secondary Structure 
AADATKGPPGGGEGEVHAGSGPGPYQDEIVISWPELHRDARYLSRVLHELGDWKGIIAI
CCCCCCCCCCCCCCCEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCEEEEE
TRGGLVPAALVARELDIRLIDTVCVVSYGAAETGGAEAKQGALQWLKTVPGDGEGWLLID
ECCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEH
DLVDTGRTAAAVREKLPKAHFATLYAKPLGRPVVDTFVKEFRQEKWIYFPWDIDYRFVTP
HHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCEEECH
IRQRGAKD
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA