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The map label for this gene is luxQ [H]

Identifier: 220916157

GI number: 220916157

Start: 1168374

End: 1169615

Strand: Direct

Name: luxQ [H]

Synonym: A2cp1_1044

Alternate gene names: 220916157

Gene position: 1168374-1169615 (Clockwise)

Preceding gene: 220916156

Following gene: 220916158

Centisome position: 23.23

GC content: 75.44

Gene sequence:

>1242_bases
GTGCACGGCAACGCCCACCCTCTCCCGGCCACCGCGCCGGAACGTCGAGCTGGGCCGCGCGACGGCGTCTGCGAGGCGCG
CCTCGCGGACGTCCTCACCGGCGACGCCCAGGTGTCGCCGGAGGAGCAGGTCGAGCGCGTGGCGGAGCGGTTCTTCGCGG
ACCCCGCGCTCGACGCGATGGTGCTGGTCGAGCCGGAGAGCGGCCGCCCTGTGGGGCTGCTCACGCGCGGACGGCTCCTC
GTGAAGCTCGCCCGCAACTTCGGCCACGAGCTGTACGCGCGGAAGCCCGTGACCCGGATCGCCGACCTGTCGCCGCTGGT
GCTGCCTCACGACCTTCCGCTGCCGCTGGCGGTCGAGCGGGCGCTGGCGCGCGAGGCGGCGTCCGTCTACGACGAGGTGA
TCGCGGTGGACGCGGCGGGGCGGTACATGGGCCACGCCGCGGTCCGCGAGCTGGCGCGCGAGCAGGGCGCTGCGCTGGAG
CGGAGCGACGCCGCGCGGGAGGCCGCCCTGGCACGCGCCAGGGACCTCGAGGAGGTGGATCGCCTTCGGGCGCGATTCCT
GGCCCACGCCACCCACGAGCTGCGCTCGCCGGTGAACGCCATCGTGGCGCTGGCGGAGCTCCTGCGCATGGCGTGCGCCC
GCAGGAGCCTCGCCGACGTGGAGGCGAAGATCCCCGTGCTCGCGCGCTCGGCGGCCGAGCTGCGCGGGACCGTCAACGAG
CTGCTCGACCTCAGCAAGCTCGAGGCCGGCCGGATGGAGGTCTCGATCGCGCCGGCGGACCTGGGCGCGCTCGTGTCCGA
GGTCGCCGCGACCGTCCGGCTCCTCGTCGGCGACGCGCCCGTCGAGGTTCGCGCCGACGCGGCACCTGGGCTCCTGCTCG
AGACCGACGGGCCCAAGGTCCGGAGGATCCTGCTCAACCTGGGCGCGAACGCCGCGAAGTTCACCAGGGCCGGCTCCGTC
CGCCTCGCGGGCGCGCCGGACGGCCGCGGCGGCGTGCTGCTGACCGTGGCGGACACCGGCTGCGGCATCGACGAGGCCGA
CCTGCCGCGGCTGTTCGTGCCGTTCAGCCAGCTCGAGGACGCTGCCACGCGCACGCGCGAAGGCACCGGCCTCGGCCTCG
CCATCACCCGCTCGCTCGCAACGCTGCTCGGCGGCACGGTCTCCGTCGAGAGCCGCCGCGGTGCGGGCACCACCTTCACG
GTCCGGCTTCCGGCCCGGCCCCCCACGAGAGAGAACGCATGA

Upstream 100 bases:

>100_bases
CGCGGCGGTGACCCGGAATCGTCACGCGCGCGCCGCAGGACGGCCACGGCCGGTGCCCAGCATGCCGTTCCGCGGCGCCC
CGCCGCATCGAGGAGCCGCC

Downstream 100 bases:

>100_bases
GCACGGCCCCGAGGATCCTGGTCATCGACGACGACGCCACCCACCTGCTCCTGACCCGCGAGCTGCTCGAGGCGGAGGGG
TACGACGTGCAGGTCCACGA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MHGNAHPLPATAPERRAGPRDGVCEARLADVLTGDAQVSPEEQVERVAERFFADPALDAMVLVEPESGRPVGLLTRGRLL
VKLARNFGHELYARKPVTRIADLSPLVLPHDLPLPLAVERALAREAASVYDEVIAVDAAGRYMGHAAVRELAREQGAALE
RSDAAREAALARARDLEEVDRLRARFLAHATHELRSPVNAIVALAELLRMACARRSLADVEAKIPVLARSAAELRGTVNE
LLDLSKLEAGRMEVSIAPADLGALVSEVAATVRLLVGDAPVEVRADAAPGLLLETDGPKVRRILLNLGANAAKFTRAGSV
RLAGAPDGRGGVLLTVADTGCGIDEADLPRLFVPFSQLEDAATRTREGTGLGLAITRSLATLLGGTVSVESRRGAGTTFT
VRLPARPPTRENA

Sequences:

>Translated_413_residues
MHGNAHPLPATAPERRAGPRDGVCEARLADVLTGDAQVSPEEQVERVAERFFADPALDAMVLVEPESGRPVGLLTRGRLL
VKLARNFGHELYARKPVTRIADLSPLVLPHDLPLPLAVERALAREAASVYDEVIAVDAAGRYMGHAAVRELAREQGAALE
RSDAAREAALARARDLEEVDRLRARFLAHATHELRSPVNAIVALAELLRMACARRSLADVEAKIPVLARSAAELRGTVNE
LLDLSKLEAGRMEVSIAPADLGALVSEVAATVRLLVGDAPVEVRADAAPGLLLETDGPKVRRILLNLGANAAKFTRAGSV
RLAGAPDGRGGVLLTVADTGCGIDEADLPRLFVPFSQLEDAATRTREGTGLGLAITRSLATLLGGTVSVESRRGAGTTFT
VRLPARPPTRENA
>Mature_413_residues
MHGNAHPLPATAPERRAGPRDGVCEARLADVLTGDAQVSPEEQVERVAERFFADPALDAMVLVEPESGRPVGLLTRGRLL
VKLARNFGHELYARKPVTRIADLSPLVLPHDLPLPLAVERALAREAASVYDEVIAVDAAGRYMGHAAVRELAREQGAALE
RSDAAREAALARARDLEEVDRLRARFLAHATHELRSPVNAIVALAELLRMACARRSLADVEAKIPVLARSAAELRGTVNE
LLDLSKLEAGRMEVSIAPADLGALVSEVAATVRLLVGDAPVEVRADAAPGLLLETDGPKVRRILLNLGANAAKFTRAGSV
RLAGAPDGRGGVLLTVADTGCGIDEADLPRLFVPFSQLEDAATRTREGTGLGLAITRSLATLLGGTVSVESRRGAGTTFT
VRLPARPPTRENA

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=31.6666666666667, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=29.7297297297297, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=29.3859649122807, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=30.0847457627119, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081816, Length=316, Percent_Identity=33.2278481012658, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=31.9444444444444, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=27.1604938271605, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=27.6315789473684, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787894, Length=279, Percent_Identity=25.8064516129032, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=27.3469387755102, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=28.8793103448276, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790861, Length=227, Percent_Identity=31.2775330396476, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=24.6808510638298, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082128, Length=242, Percent_Identity=24.7933884297521, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43780; Mature: 43780

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGNAHPLPATAPERRAGPRDGVCEARLADVLTGDAQVSPEEQVERVAERFFADPALDAM
CCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEE
VLVEPESGRPVGLLTRGRLLVKLARNFGHELYARKPVTRIADLSPLVLPHDLPLPLAVER
EEEECCCCCCEEEEHHHHHHHHHHHHHCHHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHH
ALAREAASVYDEVIAVDAAGRYMGHAAVRELAREQGAALERSDAAREAALARARDLEEVD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHH
RLRARFLAHATHELRSPVNAIVALAELLRMACARRSLADVEAKIPVLARSAAELRGTVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
LLDLSKLEAGRMEVSIAPADLGALVSEVAATVRLLVGDAPVEVRADAAPGLLLETDGPKV
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCHHH
RRILLNLGANAAKFTRAGSVRLAGAPDGRGGVLLTVADTGCGIDEADLPRLFVPFSQLED
HHHHHHCCCCHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCEEECCHHHHHH
AATRTREGTGLGLAITRSLATLLGGTVSVESRRGAGTTFTVRLPARPPTRENA
HHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MHGNAHPLPATAPERRAGPRDGVCEARLADVLTGDAQVSPEEQVERVAERFFADPALDAM
CCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEE
VLVEPESGRPVGLLTRGRLLVKLARNFGHELYARKPVTRIADLSPLVLPHDLPLPLAVER
EEEECCCCCCEEEEHHHHHHHHHHHHHCHHHHHCCCHHHHHCCCCCCCCCCCCCHHHHHH
ALAREAASVYDEVIAVDAAGRYMGHAAVRELAREQGAALERSDAAREAALARARDLEEVD
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHH
RLRARFLAHATHELRSPVNAIVALAELLRMACARRSLADVEAKIPVLARSAAELRGTVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
LLDLSKLEAGRMEVSIAPADLGALVSEVAATVRLLVGDAPVEVRADAAPGLLLETDGPKV
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEECCCHHH
RRILLNLGANAAKFTRAGSVRLAGAPDGRGGVLLTVADTGCGIDEADLPRLFVPFSQLED
HHHHHHCCCCHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCCCEEECCHHHHHH
AATRTREGTGLGLAITRSLATLLGGTVSVESRRGAGTTFTVRLPARPPTRENA
HHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7984107 [H]