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The map label for this gene is ltaE [H]

Identifier: 220916113

GI number: 220916113

Start: 1125020

End: 1126135

Strand: Reverse

Name: ltaE [H]

Synonym: A2cp1_1000

Alternate gene names: 220916113

Gene position: 1126135-1125020 (Counterclockwise)

Preceding gene: 220916114

Following gene: 220916112

Centisome position: 22.39

GC content: 73.92

Gene sequence:

>1116_bases
ATGAACCCCGGCACCCCGTCCCACCCCGCCCCGCCCGCCCCCTCGGGCCCGCTCCGCCACTTCGCCTCCGACAACTACGG
CGGCATCTGCCCCGAGGCGTTCGCGGCCATGGCCGAGGCGAACGTGGGCCACTCGCCGGGCTACGGCGACGACCGCTGGA
CGCAGGAGGCGGCCGACCTGCTGCGCGAGACGTTCGAGACCGACTGCGAGGTGTTCTTCGCGTTCAACGGCACGGCCGCG
AACTCGCTCGCGCTGGCCGCGCTCTGCCAGTCGTACCACTCGATCCTCTGCCACGAGACGGCGCACGTCGAGACCGACGA
GTGCGGCGCGCCGGAGTTCTTCTCCAACGGCACCAAGGTCCTCACCCTGCCCGGCCCGAACGGCAAGCTCCGGCCCGACG
GCATCGACCACATGGTCCGGCGCCGCACCGACATCCACTACCCGAAGCCGCGCGCGGTCTCGGTGACGCTGCCGACCGAG
CTGGGCACGCTCTACACGGTGGACGAGCTCGGCGCGATCGGCGAGCGCGCGCGCGCGAACGGGCTGCGCTTCCACATGGA
CGGCTCGCGCTTCGGCAACGCCGTGGCGGCGCTGGGCGTCGCCCCCAAGGACCTCACCTGGAAGGTGGGCGTGGACGTGC
TCTGCTTCGGCGGCACCAAGGCCGGCATGGCGGTGGGCGAGGCGATCGTGTTCTTCGACCGCGCGCTGGCGGCCGACTTC
GACTACCGCTGCAAGCAGGCCGGGCAGCTCGCGAGCAAGATGCGCTTCCTGGCGGCGCCGTGGGTGGGCATGCTCCGGGG
CGGTGCCTGGCTGCGCCACGCCCGGCACACCAACGCGATGGCCGCGCTGCTGGAGCGCGCGCTCCGCGCCGTCCCCGGGG
TGGAGATCCTCCAGCCGGTGCAGGCGAACTCGGTGTTCGCGACGCTGCCGGGCGACGCCGCCGCGCGGCTGCGCGCGAAG
GGCTGGCGCTTCTACGACTTCATCGGCTCCGGCGGCGTCCGGCTCATGTGCGCCTGGGACGTGACGCCCGCCGACGTGGA
GGCGTTCGCCGCCGACCTCCGGGTGGCGGTGGCCGGCCCGCGCGAGCGCCAGGGCGCGCACCCGGCCCTCCCGTAA

Upstream 100 bases:

>100_bases
GGTCGCGCCGGTGCGGCCCTACCACCCCTGAGATCTCCGCGTCCATCCGTTAAAACGGAACCGCTGGACAGTCGTCCGCG
AAAGCGTACAGTCCGCGGCC

Downstream 100 bases:

>100_bases
CGCGATCCCCGCGGCCGCATCCACTATGGGGTTCGCAGCGGCGCCCGGCGGCGCCGCGCCGCGGAGGACGCGATGGCCGG
CTTCGACTACGTGGTGGTGG

Product: Threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MNPGTPSHPAPPAPSGPLRHFASDNYGGICPEAFAAMAEANVGHSPGYGDDRWTQEAADLLRETFETDCEVFFAFNGTAA
NSLALAALCQSYHSILCHETAHVETDECGAPEFFSNGTKVLTLPGPNGKLRPDGIDHMVRRRTDIHYPKPRAVSVTLPTE
LGTLYTVDELGAIGERARANGLRFHMDGSRFGNAVAALGVAPKDLTWKVGVDVLCFGGTKAGMAVGEAIVFFDRALAADF
DYRCKQAGQLASKMRFLAAPWVGMLRGGAWLRHARHTNAMAALLERALRAVPGVEILQPVQANSVFATLPGDAAARLRAK
GWRFYDFIGSGGVRLMCAWDVTPADVEAFAADLRVAVAGPRERQGAHPALP

Sequences:

>Translated_371_residues
MNPGTPSHPAPPAPSGPLRHFASDNYGGICPEAFAAMAEANVGHSPGYGDDRWTQEAADLLRETFETDCEVFFAFNGTAA
NSLALAALCQSYHSILCHETAHVETDECGAPEFFSNGTKVLTLPGPNGKLRPDGIDHMVRRRTDIHYPKPRAVSVTLPTE
LGTLYTVDELGAIGERARANGLRFHMDGSRFGNAVAALGVAPKDLTWKVGVDVLCFGGTKAGMAVGEAIVFFDRALAADF
DYRCKQAGQLASKMRFLAAPWVGMLRGGAWLRHARHTNAMAALLERALRAVPGVEILQPVQANSVFATLPGDAAARLRAK
GWRFYDFIGSGGVRLMCAWDVTPADVEAFAADLRVAVAGPRERQGAHPALP
>Mature_371_residues
MNPGTPSHPAPPAPSGPLRHFASDNYGGICPEAFAAMAEANVGHSPGYGDDRWTQEAADLLRETFETDCEVFFAFNGTAA
NSLALAALCQSYHSILCHETAHVETDECGAPEFFSNGTKVLTLPGPNGKLRPDGIDHMVRRRTDIHYPKPRAVSVTLPTE
LGTLYTVDELGAIGERARANGLRFHMDGSRFGNAVAALGVAPKDLTWKVGVDVLCFGGTKAGMAVGEAIVFFDRALAADF
DYRCKQAGQLASKMRFLAAPWVGMLRGGAWLRHARHTNAMAALLERALRAVPGVEILQPVQANSVFATLPGDAAARLRAK
GWRFYDFIGSGGVRLMCAWDVTPADVEAFAADLRVAVAGPRERQGAHPALP

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=369, Percent_Identity=26.0162601626016, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 39708; Mature: 39708

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPGTPSHPAPPAPSGPLRHFASDNYGGICPEAFAAMAEANVGHSPGYGDDRWTQEAADL
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LRETFETDCEVFFAFNGTAANSLALAALCQSYHSILCHETAHVETDECGAPEFFSNGTKV
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEE
LTLPGPNGKLRPDGIDHMVRRRTDIHYPKPRAVSVTLPTELGTLYTVDELGAIGERARAN
EEECCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHCC
GLRFHMDGSRFGNAVAALGVAPKDLTWKVGVDVLCFGGTKAGMAVGEAIVFFDRALAADF
CEEEEECCHHHCCHHHHHCCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHCCC
DYRCKQAGQLASKMRFLAAPWVGMLRGGAWLRHARHTNAMAALLERALRAVPGVEILQPV
CHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
QANSVFATLPGDAAARLRAKGWRFYDFIGSGGVRLMCAWDVTPADVEAFAADLRVAVAGP
CCCCEEEECCCHHHHHHHHCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHEEEECCC
RERQGAHPALP
HHHCCCCCCCC
>Mature Secondary Structure
MNPGTPSHPAPPAPSGPLRHFASDNYGGICPEAFAAMAEANVGHSPGYGDDRWTQEAADL
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LRETFETDCEVFFAFNGTAANSLALAALCQSYHSILCHETAHVETDECGAPEFFSNGTKV
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEE
LTLPGPNGKLRPDGIDHMVRRRTDIHYPKPRAVSVTLPTELGTLYTVDELGAIGERARAN
EEECCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHCC
GLRFHMDGSRFGNAVAALGVAPKDLTWKVGVDVLCFGGTKAGMAVGEAIVFFDRALAADF
CEEEEECCHHHCCHHHHHCCCCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHCCC
DYRCKQAGQLASKMRFLAAPWVGMLRGGAWLRHARHTNAMAALLERALRAVPGVEILQPV
CHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
QANSVFATLPGDAAARLRAKGWRFYDFIGSGGVRLMCAWDVTPADVEAFAADLRVAVAGP
CCCCEEEECCCHHHHHHHHCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHEEEECCC
RERQGAHPALP
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]