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The map label for this gene is ctaD [H]

Identifier: 220915970

GI number: 220915970

Start: 960725

End: 962389

Strand: Direct

Name: ctaD [H]

Synonym: A2cp1_0856

Alternate gene names: 220915970

Gene position: 960725-962389 (Clockwise)

Preceding gene: 220915969

Following gene: 220915971

Centisome position: 19.1

GC content: 65.59

Gene sequence:

>1665_bases
ATGAGTCCATCCCACGCAAGTGACGTTCCCGTGTACAACCCGCGGAACTACCTCAACTCGCCCGCGACCGGCCTGAAGTC
CTGGATGCTGACCCAGGACCACAAGCGGATCGGGGTGATGTTCCTGGTCGCGGCCACGGTGTTCTTCGCCGTCGGCGGCC
TGTTCGCCATGCTCATCCGGATCGAGCTGCTCACGCCCGGTCCGACGATCATGGACGCGATGACGTACAACCGGATGTTC
ACGCTCCACGGCGTGGTCATGATCTTCCTGTTCATGATCCCCGCCATCCCGAGCGGCTTCGGCAACTTCCTGGTGCCGCT
CATGCTCGGGGCCAAGGACGTGGCGTTCCCGAAGCTGAACCTCCTCAGCTTCTACCTCTACCTGCTGGGCGCCGCGATCG
CGCTGTACGGGATGATCCACGGCGGCGCGGACACCGGCTGGACGTTCTACACGCCGTACTCGACCACCACCGCCACCAAG
GTGGTGCCGATCCTGCTCGGCGCGTTCGTCCTGGGGTTCTCGTCGATCCTCACCGGCCTGAACTTCATCGTCACCACGCA
CACCATGCGCGCCCCCGGGATCGGCTGGAACCGGGTGCCGCTGTTCGTGTGGTCGATCTACGCGACCAGCATCATCCAGA
TCCTCGCCACGCCGGTGCTGGGCATGACGCTGCTGCTCGTCGCGGTGGAGCACGCGTTCGGCTGGGGCATCTTCGATCCG
GCGCGCGGCGGCGACCCGGTGCTGTTCCAGCACTTCTTCTGGTTCTACTCGCACCCCGCCGTCTACATCATGGTGCTGCC
CGCGATGGCGGTGATCTCCGAGGTGGTCTGCGCGTTCTCGCGCAAGAACATCTTCGGCTACAAGGCGGTCGCCTACTCCT
CGCTCGGCATCGCCTTCGTCGGCTTCTTCACCTGGGGCCACCACCTGTTCGTCTCGGGCCAGTCGGCCTTCGACGCCGGC
GTGTTCGGGATCCTCTCGATGTTCGTGGGCATCTTCACGGCCATCAAGGTCTTCAACTGGACCGCCACGCTGTACCAGGG
CTCGATCGCGTTCAAGACGCCGTTCGCCTACTTCGTCGGCTTCCTGTTCTTCCTGGTGTTCGGCGGGATGACCGGCGTGG
CGGTCGCCACCGTGTCGCTCGACGTCCACTGGCACGACACGTACTTCGTGGTGGCGCACTTCCACTTCATCATGGTGGGC
GCGACCGTGATGGCGTTCCTCGCCGCGCTCCACTACTGGTTCCCGAAGATCACCGGCCGCATGTACCCGGAGGGCTGGGG
GCTGGTGGGCGCGGTGATGGTGATCCTGGGCTTCAACTTCACCTTCATCCCGCAGTTCCTGCTCGGGAACGAGGGCATGC
CGCGCCGGTACTTCTCCTACCCGGAGCGGTTCTGGGCGCTCAACGTCGCCTCCACCGCCGGCGCCTCGGTGCTGGCGATG
GGCCTCGTCATCATCCTCGTCTACCTGCTGGTGGCGCTGAAGTGGGGCCCGATCGCCGGCTCGAACCCGTGGCACTCGCG
CGGATACGAGTGGGACACGGCCTCGCCGCCGCTCCCCGAGAACTTCGAGGAGACCCCGGTCTACACGCGCGGACCGCACG
AGTACGACGAGGACTCCTACGCCAACCCTCCCCCGGTCGCCCCCGAGCCGAAGCATGCAAGCTAG

Upstream 100 bases:

>100_bases
CAGGGCAAGCTCGCACCGCCCGAGGCGGCGGCCATCGTCGAGTTCATCAAGTCCTTGAAGACCCCGGCGGTCCAGAGCGG
TCCGTCGGAGGGCCCGGTCT

Downstream 100 bases:

>100_bases
CCCGCTCGCACACCATTTCGAGAACATCGAGAAGCAGTCGCACGCCGAGCGGCTCGGCATGTGGCTGTTCCTCGCCTCCG
AGGTGCTGCTGTTCACCGCG

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSPSHASDVPVYNPRNYLNSPATGLKSWMLTQDHKRIGVMFLVAATVFFAVGGLFAMLIRIELLTPGPTIMDAMTYNRMF
TLHGVVMIFLFMIPAIPSGFGNFLVPLMLGAKDVAFPKLNLLSFYLYLLGAAIALYGMIHGGADTGWTFYTPYSTTTATK
VVPILLGAFVLGFSSILTGLNFIVTTHTMRAPGIGWNRVPLFVWSIYATSIIQILATPVLGMTLLLVAVEHAFGWGIFDP
ARGGDPVLFQHFFWFYSHPAVYIMVLPAMAVISEVVCAFSRKNIFGYKAVAYSSLGIAFVGFFTWGHHLFVSGQSAFDAG
VFGILSMFVGIFTAIKVFNWTATLYQGSIAFKTPFAYFVGFLFFLVFGGMTGVAVATVSLDVHWHDTYFVVAHFHFIMVG
ATVMAFLAALHYWFPKITGRMYPEGWGLVGAVMVILGFNFTFIPQFLLGNEGMPRRYFSYPERFWALNVASTAGASVLAM
GLVIILVYLLVALKWGPIAGSNPWHSRGYEWDTASPPLPENFEETPVYTRGPHEYDEDSYANPPPVAPEPKHAS

Sequences:

>Translated_554_residues
MSPSHASDVPVYNPRNYLNSPATGLKSWMLTQDHKRIGVMFLVAATVFFAVGGLFAMLIRIELLTPGPTIMDAMTYNRMF
TLHGVVMIFLFMIPAIPSGFGNFLVPLMLGAKDVAFPKLNLLSFYLYLLGAAIALYGMIHGGADTGWTFYTPYSTTTATK
VVPILLGAFVLGFSSILTGLNFIVTTHTMRAPGIGWNRVPLFVWSIYATSIIQILATPVLGMTLLLVAVEHAFGWGIFDP
ARGGDPVLFQHFFWFYSHPAVYIMVLPAMAVISEVVCAFSRKNIFGYKAVAYSSLGIAFVGFFTWGHHLFVSGQSAFDAG
VFGILSMFVGIFTAIKVFNWTATLYQGSIAFKTPFAYFVGFLFFLVFGGMTGVAVATVSLDVHWHDTYFVVAHFHFIMVG
ATVMAFLAALHYWFPKITGRMYPEGWGLVGAVMVILGFNFTFIPQFLLGNEGMPRRYFSYPERFWALNVASTAGASVLAM
GLVIILVYLLVALKWGPIAGSNPWHSRGYEWDTASPPLPENFEETPVYTRGPHEYDEDSYANPPPVAPEPKHAS
>Mature_553_residues
SPSHASDVPVYNPRNYLNSPATGLKSWMLTQDHKRIGVMFLVAATVFFAVGGLFAMLIRIELLTPGPTIMDAMTYNRMFT
LHGVVMIFLFMIPAIPSGFGNFLVPLMLGAKDVAFPKLNLLSFYLYLLGAAIALYGMIHGGADTGWTFYTPYSTTTATKV
VPILLGAFVLGFSSILTGLNFIVTTHTMRAPGIGWNRVPLFVWSIYATSIIQILATPVLGMTLLLVAVEHAFGWGIFDPA
RGGDPVLFQHFFWFYSHPAVYIMVLPAMAVISEVVCAFSRKNIFGYKAVAYSSLGIAFVGFFTWGHHLFVSGQSAFDAGV
FGILSMFVGIFTAIKVFNWTATLYQGSIAFKTPFAYFVGFLFFLVFGGMTGVAVATVSLDVHWHDTYFVVAHFHFIMVGA
TVMAFLAALHYWFPKITGRMYPEGWGLVGAVMVILGFNFTFIPQFLLGNEGMPRRYFSYPERFWALNVASTAGASVLAMG
LVIILVYLLVALKWGPIAGSNPWHSRGYEWDTASPPLPENFEETPVYTRGPHEYDEDSYANPPPVAPEPKHAS

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=512, Percent_Identity=37.109375, Blast_Score=324, Evalue=1e-88,
Organism=Escherichia coli, GI1786634, Length=540, Percent_Identity=34.2592592592593, Blast_Score=300, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6226519, Length=530, Percent_Identity=34.3396226415094, Blast_Score=325, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=36.0248447204969, Blast_Score=218, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=34.412955465587, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61121; Mature: 60990

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCC
>Mature Secondary Structure 
SPSHASDVPVYNPRNYLNSPATGLKSWMLTQDHKRIGVMFLVAATVFFAVGGLFAMLIR
CCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH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CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8399373 [H]