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The map label for this gene is dfrA [H]

Identifier: 220915943

GI number: 220915943

Start: 926673

End: 927692

Strand: Direct

Name: dfrA [H]

Synonym: A2cp1_0829

Alternate gene names: 220915943

Gene position: 926673-927692 (Clockwise)

Preceding gene: 220915942

Following gene: 220915945

Centisome position: 18.43

GC content: 79.12

Gene sequence:

>1020_bases
GTGAACGTCCTCGTGACCGGCGGTACGGGCCTGGTGGGCGGCGCGGTGGCGCGCGCCCTGCTCGCGCGCGGGCACTCGGT
GCGGCTGTACGCCCGCGCCTCCAGCGACGCCGCCGCGCTGGAGGCGGCCGGCGCGGAGGTGGCGCGCGGCGAGCTGGACG
ACCGGCCGGCGCTGCGCGCGGCGCTGGCGGGCCGCGACGCGGTGGTCCACTCGGCGGGCGTGGTGGGCTTCGGGCCGGGG
CTGGAGGCGGCGCTCGAGGCGGTCAACGTGCGCGCCGTCGAGGCGGTGCTGGGCGCCGCGCTGGACGCGGGGGTGTCGCG
CGCCGTGCTCACCTCGTCCACGGCGGTCATGGGCGGCACCGCCGCGCCGGAGGTGGCCGACGAGGCCAGCGCCGGCAACG
CCGAGGCGCTCGGGATGCCCTACTTCGTCTCGAAGCTCCGGGGTGAGCGGGCCGCGCGGGCGCTCGCCGCGCGCGGCCTG
GCGCTGGTGGTGGTCCGCCCGGCGTACGTGCTCGGGCCGGGCGACGTCCACGGCTCGTCGGCGTCGATCCTGCTCGCGTT
CGCGCAGCGCCGCATCCCCGCGTACGTGGAGGGCGGCGCGTCCTTCTGCGACGTGCGCGACGTGGCGGAGGGGCACGTGG
CCGCCCTGGAGCGCGGGCGCCCCGGCGAGGCGTACGTGCTCGCCGGCCACAACCTGGCCATGTCGGAGATGATCCGGCGC
GCCTGCGCCATCGCCGGCGTCCCGCCCCCGCCGCGCGTGCCGGTGCCGCTGGCGCTCGGGTTCGCCGCGGTGCAGGAGCT
GGCGGCGCGCGCGGCCGGCCGGCGGCCGCGGACGAGCCGCGGCCTGGTCCGCGCCAGCGCGCTGTACACGTTCGCGTCCT
CGGCGAAGGCGGAGCGCGAGCTCGGCTACCGCGTCCGACCGTTCGAGGAGATGGTCCGCGACACCTACCGCTGGGCCATC
GCCACCGGCCGCCTGCGGCCGGACACGCCCGAGCTGAAGGCGCTGAACGACGGCCCGTGA

Upstream 100 bases:

>100_bases
CCGTTCGAGCTGGACCAGCTCCTCGAGACGGTGGCCCGGCACGCGCGGCGCCGGTGACCGGGTCCTTGTCGTGGCCGCAG
GGCCGGGGTAGACCGGCCCG

Downstream 100 bases:

>100_bases
GCCGCGAACACCTTCGGGTCGCGGGTCACGTCCTCCGCTGCTCCGCTGGCGCGGGTCACGCCTCCGGCCCGGCCGCGCCG
TTCTCCTCGCTCGCGCCCGC

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNVLVTGGTGLVGGAVARALLARGHSVRLYARASSDAAALEAAGAEVARGELDDRPALRAALAGRDAVVHSAGVVGFGPG
LEAALEAVNVRAVEAVLGAALDAGVSRAVLTSSTAVMGGTAAPEVADEASAGNAEALGMPYFVSKLRGERAARALAARGL
ALVVVRPAYVLGPGDVHGSSASILLAFAQRRIPAYVEGGASFCDVRDVAEGHVAALERGRPGEAYVLAGHNLAMSEMIRR
ACAIAGVPPPPRVPVPLALGFAAVQELAARAAGRRPRTSRGLVRASALYTFASSAKAERELGYRVRPFEEMVRDTYRWAI
ATGRLRPDTPELKALNDGP

Sequences:

>Translated_339_residues
MNVLVTGGTGLVGGAVARALLARGHSVRLYARASSDAAALEAAGAEVARGELDDRPALRAALAGRDAVVHSAGVVGFGPG
LEAALEAVNVRAVEAVLGAALDAGVSRAVLTSSTAVMGGTAAPEVADEASAGNAEALGMPYFVSKLRGERAARALAARGL
ALVVVRPAYVLGPGDVHGSSASILLAFAQRRIPAYVEGGASFCDVRDVAEGHVAALERGRPGEAYVLAGHNLAMSEMIRR
ACAIAGVPPPPRVPVPLALGFAAVQELAARAAGRRPRTSRGLVRASALYTFASSAKAERELGYRVRPFEEMVRDTYRWAI
ATGRLRPDTPELKALNDGP
>Mature_339_residues
MNVLVTGGTGLVGGAVARALLARGHSVRLYARASSDAAALEAAGAEVARGELDDRPALRAALAGRDAVVHSAGVVGFGPG
LEAALEAVNVRAVEAVLGAALDAGVSRAVLTSSTAVMGGTAAPEVADEASAGNAEALGMPYFVSKLRGERAARALAARGL
ALVVVRPAYVLGPGDVHGSSASILLAFAQRRIPAYVEGGASFCDVRDVAEGHVAALERGRPGEAYVLAGHNLAMSEMIRR
ACAIAGVPPPPRVPVPLALGFAAVQELAARAAGRRPRTSRGLVRASALYTFASSAKAERELGYRVRPFEEMVRDTYRWAI
ATGRLRPDTPELKALNDGP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71987463, Length=337, Percent_Identity=27.5964391691395, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 34780; Mature: 34780

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLVTGGTGLVGGAVARALLARGHSVRLYARASSDAAALEAAGAEVARGELDDRPALRA
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHCCCHHHCCCCCCCHHHHH
ALAGRDAVVHSAGVVGFGPGLEAALEAVNVRAVEAVLGAALDAGVSRAVLTSSTAVMGGT
HHCCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEECCC
AAPEVADEASAGNAEALGMPYFVSKLRGERAARALAARGLALVVVRPAYVLGPGDVHGSS
CCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCCC
ASILLAFAQRRIPAYVEGGASFCDVRDVAEGHVAALERGRPGEAYVLAGHNLAMSEMIRR
HHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
ACAIAGVPPPPRVPVPLALGFAAVQELAARAAGRRPRTSRGLVRASALYTFASSAKAERE
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGYRVRPFEEMVRDTYRWAIATGRLRPDTPELKALNDGP
CCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVLVTGGTGLVGGAVARALLARGHSVRLYARASSDAAALEAAGAEVARGELDDRPALRA
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHCCCHHHCCCCCCCHHHHH
ALAGRDAVVHSAGVVGFGPGLEAALEAVNVRAVEAVLGAALDAGVSRAVLTSSTAVMGGT
HHCCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEECCC
AAPEVADEASAGNAEALGMPYFVSKLRGERAARALAARGLALVVVRPAYVLGPGDVHGSS
CCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCCC
ASILLAFAQRRIPAYVEGGASFCDVRDVAEGHVAALERGRPGEAYVLAGHNLAMSEMIRR
HHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
ACAIAGVPPPPRVPVPLALGFAAVQELAARAAGRRPRTSRGLVRASALYTFASSAKAERE
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGYRVRPFEEMVRDTYRWAIATGRLRPDTPELKALNDGP
CCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]