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The map label for this gene is cdd [H]

Identifier: 220915773

GI number: 220915773

Start: 728204

End: 728608

Strand: Direct

Name: cdd [H]

Synonym: A2cp1_0654

Alternate gene names: 220915773

Gene position: 728204-728608 (Clockwise)

Preceding gene: 220915772

Following gene: 220915774

Centisome position: 14.48

GC content: 81.48

Gene sequence:

>405_bases
GTGGCGCCTCCGGTCGGCACCCGCGACGAGCTCGTCCGCGCCGCCCGCGCCGCGCGCGGCCGGGCCTACGCCCCGTACTC
GCGCTTCCGGGTGGGCGCGGCGGTGCGCGCCGGCGGGGCCGTTCACGCGGGGTGCAACGTCGAGAACGCGAGCTACGGCC
TGACCGTCTGCGCCGAGCGCGCCGCGGTCGCGGCCGCGGTCGCCGCGGGAGCCCGCCGCCTGGAGGCGGTGGCGGTGGCG
AGCGGCACCAGCCCGCCGACCCCGCCCTGCGGGGCCTGCCTCCAGACGCTCGCCGAGTTCGGCGGGCCGGACCTCCCGGT
GGTCCTCGCCGGCGCCCGCGGCGCCCGGGTCGAGACCACCCTCGGCGCGCTGCTGCCCAGCGCGTTCGGGCGCCGGTTCC
TGTAG

Upstream 100 bases:

>100_bases
ACGCGCGAGGACGAGCGCTTCGGCACGCACCTGCGCTTCGTGGAGATCCCGCTCGACGCGGAGCTCGCCATCGCGCGCTT
CCTCCAGCAGGCCTGAGCGC

Downstream 100 bases:

>100_bases
GCGGTCGTCCGGGGCGCCGGCGCGGGCGAACGGCCGCACGCGCGTGCGATTGACGCCGGGGGGCCCCGGACCTATGAACG
GCGGCGTGCAGGTCTTCCGC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MAPPVGTRDELVRAARAARGRAYAPYSRFRVGAAVRAGGAVHAGCNVENASYGLTVCAERAAVAAAVAAGARRLEAVAVA
SGTSPPTPPCGACLQTLAEFGGPDLPVVLAGARGARVETTLGALLPSAFGRRFL

Sequences:

>Translated_134_residues
MAPPVGTRDELVRAARAARGRAYAPYSRFRVGAAVRAGGAVHAGCNVENASYGLTVCAERAAVAAAVAAGARRLEAVAVA
SGTSPPTPPCGACLQTLAEFGGPDLPVVLAGARGARVETTLGALLPSAFGRRFL
>Mature_133_residues
APPVGTRDELVRAARAARGRAYAPYSRFRVGAAVRAGGAVHAGCNVENASYGLTVCAERAAVAAAVAAGARRLEAVAVAS
GTSPPTPPCGACLQTLAEFGGPDLPVVLAGARGARVETTLGALLPSAFGRRFL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=123, Percent_Identity=42.2764227642276, Blast_Score=99, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17540514, Length=122, Percent_Identity=50.8196721311475, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17551074, Length=122, Percent_Identity=45.0819672131148, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323274, Length=124, Percent_Identity=41.9354838709677, Blast_Score=93, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920920, Length=138, Percent_Identity=43.4782608695652, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24582741, Length=126, Percent_Identity=42.0634920634921, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24582744, Length=105, Percent_Identity=46.6666666666667, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13416; Mature: 13284

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPVGTRDELVRAARAARGRAYAPYSRFRVGAAVRAGGAVHAGCNVENASYGLTVCAER
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHH
AAVAAAVAAGARRLEAVAVASGTSPPTPPCGACLQTLAEFGGPDLPVVLAGARGARVETT
HHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHH
LGALLPSAFGRRFL
HHHHHHHHHCCCCC
>Mature Secondary Structure 
APPVGTRDELVRAARAARGRAYAPYSRFRVGAAVRAGGAVHAGCNVENASYGLTVCAER
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHH
AAVAAAVAAGARRLEAVAVASGTSPPTPPCGACLQTLAEFGGPDLPVVLAGARGARVETT
HHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHH
LGALLPSAFGRRFL
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]