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The map label for this gene is rnz [H]

Identifier: 220915549

GI number: 220915549

Start: 484580

End: 485536

Strand: Direct

Name: rnz [H]

Synonym: A2cp1_0430

Alternate gene names: 220915549

Gene position: 484580-485536 (Clockwise)

Preceding gene: 220915548

Following gene: 220915550

Centisome position: 9.64

GC content: 75.44

Gene sequence:

>957_bases
GTGCCGCCGGGCCCGCGCTTCGACTACATTCCGGCCGGCATGCTCCGCCTGACCTTCCTCGGCACCTCCGCCGCCCAGCC
CACCATCCGGCGCAACCTCACCGGTCACGCGGTGCGGCGCGAGCGCGAGCTGTTCCTGGTGGACTGCGGCGAGGGCACCC
AGCGCCAGCTCATCCAGTTCGGCGCCGGGTTCGACGTGGCGGCCATCTTCTTCACGCACTTCCACGCCGATCACTACCTC
GGCGCGATCGGCTTCCTGCGGACGCTGTCCATGCAGAACCGCGCCGAGCCGCTCGACCTCTACGGCCCGCGCCCGGCGAA
GCGCCTGCTCGAGACCATGCTGTTCACCGGCGCGGAGCGCTTCAGCTACGAGGTGCGCATCCACGAGGTGCGCGCGGGCG
AGGCGGTGCGGCGCGACGGCTGCGCCATGGTCCCGTTCCCCACCGAGCACCGGACGCCGTCGCTCGGCTGGGCGCTCCGC
GAGGACGCGCGGCCGGGCCGCTTCCACCCGGACAAGGCCGAGGCGCTCGGGATCCCGAAGGGCCCGCTGTTCGGCGCGCT
CCAGCGCGGCGAGCCGGTGACGCTGCCCGACGGCCGCACCGTGCGTCCGGAGGAGGTGGTCGAGCCGGCGCGGCGCGGCC
GGGCGCTGGTCATCACCGGCGACACGCGCCCGTGCGCGGCGACGGTGGAGGCGGCGCGCGGCGCGGACGTGCTGGTGCAC
GACTGCACCTTCGGCGACGGCGAGGCGGAGCGCGCCGAGGAGACGCTCCACTCGACCGCCCGCGGCGCGGCGCAGGTGGC
GCACGACGCCGGCGTGGTCCGGCTCGTGCTCACGCACCTGTCCACCCGCTACGACCGCGCCTGGGAGCCGCTGGTGGAGC
AGGCGCGCGAGGTCTGGCAGGGCCCGCTCGACGTGGCGCACGACGGCATGGTCCTCGAGGTCCCGCTGCCGGCGTGA

Upstream 100 bases:

>100_bases
CGGTGGCGTTCGCGGGGCTCGCCCGCGCGGTCTGGCTCCGGTCCATCTCCCGGTACACCTCGGCGTCCTCCTAGCGAGGG
CTGCGCCCCATCGATCCGGC

Downstream 100 bases:

>100_bases
CGGGGCGGACTCGCCGTGCCTCGCCCATAGGCGGGGCCATCGGCATGGCCTGCGCTGGACCGGGCGGATCCCGCCCTTAG
GTTCCTCGCATGATCACCGT

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPPGPRFDYIPAGMLRLTFLGTSAAQPTIRRNLTGHAVRRERELFLVDCGEGTQRQLIQFGAGFDVAAIFFTHFHADHYL
GAIGFLRTLSMQNRAEPLDLYGPRPAKRLLETMLFTGAERFSYEVRIHEVRAGEAVRRDGCAMVPFPTEHRTPSLGWALR
EDARPGRFHPDKAEALGIPKGPLFGALQRGEPVTLPDGRTVRPEEVVEPARRGRALVITGDTRPCAATVEAARGADVLVH
DCTFGDGEAERAEETLHSTARGAAQVAHDAGVVRLVLTHLSTRYDRAWEPLVEQAREVWQGPLDVAHDGMVLEVPLPA

Sequences:

>Translated_318_residues
MPPGPRFDYIPAGMLRLTFLGTSAAQPTIRRNLTGHAVRRERELFLVDCGEGTQRQLIQFGAGFDVAAIFFTHFHADHYL
GAIGFLRTLSMQNRAEPLDLYGPRPAKRLLETMLFTGAERFSYEVRIHEVRAGEAVRRDGCAMVPFPTEHRTPSLGWALR
EDARPGRFHPDKAEALGIPKGPLFGALQRGEPVTLPDGRTVRPEEVVEPARRGRALVITGDTRPCAATVEAARGADVLVH
DCTFGDGEAERAEETLHSTARGAAQVAHDAGVVRLVLTHLSTRYDRAWEPLVEQAREVWQGPLDVAHDGMVLEVPLPA
>Mature_317_residues
PPGPRFDYIPAGMLRLTFLGTSAAQPTIRRNLTGHAVRRERELFLVDCGEGTQRQLIQFGAGFDVAAIFFTHFHADHYLG
AIGFLRTLSMQNRAEPLDLYGPRPAKRLLETMLFTGAERFSYEVRIHEVRAGEAVRRDGCAMVPFPTEHRTPSLGWALRE
DARPGRFHPDKAEALGIPKGPLFGALQRGEPVTLPDGRTVRPEEVVEPARRGRALVITGDTRPCAATVEAARGADVLVHD
CTFGDGEAERAEETLHSTARGAAQVAHDAGVVRLVLTHLSTRYDRAWEPLVEQAREVWQGPLDVAHDGMVLEVPLPA

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Homo sapiens, GI8922122, Length=360, Percent_Identity=30.8333333333333, Blast_Score=155, Evalue=3e-38,
Organism=Escherichia coli, GI87082078, Length=307, Percent_Identity=36.1563517915309, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 35044; Mature: 34913

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPGPRFDYIPAGMLRLTFLGTSAAQPTIRRNLTGHAVRRERELFLVDCGEGTQRQLIQF
CCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCHHHHHCCCEEEEEECCCCHHHHHHHH
GAGFDVAAIFFTHFHADHYLGAIGFLRTLSMQNRAEPLDLYGPRPAKRLLETMLFTGAER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHH
FSYEVRIHEVRAGEAVRRDGCAMVPFPTEHRTPSLGWALREDARPGRFHPDKAEALGIPK
EEEEEEEEEECCCHHHHHCCCEECCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHCCCCC
GPLFGALQRGEPVTLPDGRTVRPEEVVEPARRGRALVITGDTRPCAATVEAARGADVLVH
CCHHHHHCCCCCEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCEEEEE
DCTFGDGEAERAEETLHSTARGAAQVAHDAGVVRLVLTHLSTRYDRAWEPLVEQAREVWQ
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GPLDVAHDGMVLEVPLPA
CCCHHCCCCEEEEECCCC
>Mature Secondary Structure 
PPGPRFDYIPAGMLRLTFLGTSAAQPTIRRNLTGHAVRRERELFLVDCGEGTQRQLIQF
CCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCHHHHHCCCEEEEEECCCCHHHHHHHH
GAGFDVAAIFFTHFHADHYLGAIGFLRTLSMQNRAEPLDLYGPRPAKRLLETMLFTGAER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHH
FSYEVRIHEVRAGEAVRRDGCAMVPFPTEHRTPSLGWALREDARPGRFHPDKAEALGIPK
EEEEEEEEEECCCHHHHHCCCEECCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHCCCCC
GPLFGALQRGEPVTLPDGRTVRPEEVVEPARRGRALVITGDTRPCAATVEAARGADVLVH
CCHHHHHCCCCCEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCEEEEE
DCTFGDGEAERAEETLHSTARGAAQVAHDAGVVRLVLTHLSTRYDRAWEPLVEQAREVWQ
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GPLDVAHDGMVLEVPLPA
CCCHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA