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The map label for this gene is resA [H]

Identifier: 220915486

GI number: 220915486

Start: 412377

End: 412952

Strand: Direct

Name: resA [H]

Synonym: A2cp1_0367

Alternate gene names: 220915486

Gene position: 412377-412952 (Clockwise)

Preceding gene: 220915484

Following gene: 220915487

Centisome position: 8.2

GC content: 77.78

Gene sequence:

>576_bases
ATGGACGGGGCCGGCGACCGCGGTCGCGCGGCGCGGCCAGCGCGCGGCGGCGCCCGGGGGGGGCTGGCGCTCCTCGCCGG
CGCTGCGCTGGCGATCGGTGCACTGGTCGTGGCCGACCGCCGCGCGGCGGCGGGGCGAGCGCCGGGCCTGGACGAGCTCG
CGCCGCCGCTGGTGGTGACCTCCGTGGGCGGAGGCGGCGCGATCGACCTGGGGAAGCTGCGGGGGCGCGCCGTCGCGGTG
AACTTCTGGGCACCCTGGTGCGGCCCGTGCCGGGCCGAGCTTCCGGACCTGGCCGAGGTGAAGCGGGAGCTGGCGGACGC
CTGCGTGGAGCTGATCGGGGTCGCTGGCGACGGCGGGCGCGAGGAGGTGGCGCAGGTCGCCGCAGGGCAGCCGTATCCGA
TGGGCTTCGACGCGGACGGCGCGGCGATGCGCGCGTGGCGCGTGGACGCGGTGCCGACCACGTACCTCGTCGATCCCGGA
GGCAAGATCCACGCGGTCATCTCCGGCGCCGTCGGCCGGGCAGAGCTCCTCGAGGCCCTTCGTCCCATCATCCCGGCGAC
GTGCCCGCGGAGCTGA

Upstream 100 bases:

>100_bases
AGGCGTTTCAGGCAGGAGCCGGGCACTTCAGCCTGAAGCGCGACCGCGCCGCGGCACGGGGGTTGCTCCGTGAGCGAGCA
TGGAACGTGGACCGGAGATC

Downstream 100 bases:

>100_bases
GCCCGGCAGCGCGACCGCTTCGCATTGAAGCGCGCGCTTTCCGATTGAAACGTCCGCGCCGCACGGCGGCGCTCCAGGGC
GGCGGGATCTCGACGGATGC

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MDGAGDRGRAARPARGGARGGLALLAGAALAIGALVVADRRAAAGRAPGLDELAPPLVVTSVGGGGAIDLGKLRGRAVAV
NFWAPWCGPCRAELPDLAEVKRELADACVELIGVAGDGGREEVAQVAAGQPYPMGFDADGAAMRAWRVDAVPTTYLVDPG
GKIHAVISGAVGRAELLEALRPIIPATCPRS

Sequences:

>Translated_191_residues
MDGAGDRGRAARPARGGARGGLALLAGAALAIGALVVADRRAAAGRAPGLDELAPPLVVTSVGGGGAIDLGKLRGRAVAV
NFWAPWCGPCRAELPDLAEVKRELADACVELIGVAGDGGREEVAQVAAGQPYPMGFDADGAAMRAWRVDAVPTTYLVDPG
GKIHAVISGAVGRAELLEALRPIIPATCPRS
>Mature_191_residues
MDGAGDRGRAARPARGGARGGLALLAGAALAIGALVVADRRAAAGRAPGLDELAPPLVVTSVGGGGAIDLGKLRGRAVAV
NFWAPWCGPCRAELPDLAEVKRELADACVELIGVAGDGGREEVAQVAAGQPYPMGFDADGAAMRAWRVDAVPTTYLVDPG
GKIHAVISGAVGRAELLEALRPIIPATCPRS

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 19216; Mature: 19216

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGAGDRGRAARPARGGARGGLALLAGAALAIGALVVADRRAAAGRAPGLDELAPPLVVT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHCCCEEEE
SVGGGGAIDLGKLRGRAVAVNFWAPWCGPCRAELPDLAEVKRELADACVELIGVAGDGGR
ECCCCCCEEHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCH
EEVAQVAAGQPYPMGFDADGAAMRAWRVDAVPTTYLVDPGGKIHAVISGAVGRAELLEAL
HHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCEEEEEEECCCCHHHHHHHH
RPIIPATCPRS
HHHCCCCCCCC
>Mature Secondary Structure
MDGAGDRGRAARPARGGARGGLALLAGAALAIGALVVADRRAAAGRAPGLDELAPPLVVT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHCCCEEEE
SVGGGGAIDLGKLRGRAVAVNFWAPWCGPCRAELPDLAEVKRELADACVELIGVAGDGGR
ECCCCCCEEHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCH
EEVAQVAAGQPYPMGFDADGAAMRAWRVDAVPTTYLVDPGGKIHAVISGAVGRAELLEAL
HHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCEEEEEEECCCCHHHHHHHH
RPIIPATCPRS
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 12637552 [H]