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The map label for this gene is rsmB [H]

Identifier: 220915419

GI number: 220915419

Start: 333211

End: 334524

Strand: Direct

Name: rsmB [H]

Synonym: A2cp1_0298

Alternate gene names: 220915419

Gene position: 333211-334524 (Clockwise)

Preceding gene: 220915418

Following gene: 220915420

Centisome position: 6.63

GC content: 79.0

Gene sequence:

>1314_bases
ATGACCCGGAAGCCCCACCCCCAGCGCCCGCCGCGCAACGACCTCGTGGACGCCCTGGTGCTCGAGGTGCACGGCCTCGT
GCACGACCAGGGCTGGCTCGCCGACCGGGCGCTGGAGCGCGTGCTCCGGCGCGAGCGCGCGCTGTGGGCGAACGAGCGCC
GCGCCGTCGCGGAGGCGGTCTACGGGATCCTGCGCGCGCAGGGGCAGCTCGACTTCCTGCTGGGCGGCAGCCCGCCGCTC
GCCACCCGCTACGCCGCCTGGCTGGTGCGGGCGGCCGGGGTGGCGCCGGCCCAGGCCGCGGCGCGGCTCGGCGCGTCGCC
GCGCGCGCTCGCCGGGCTGGCCGAGGCGGACGCGCGCGTCGCCGCCATCCCGGATCCGCTGGACCGCTTCGCGGTGGAGG
CGTCGCTGCCGCGCTGGATCGCCGAGCGGCTCGTGTCGGAGCTGGGCGAGGCGGAGGCGCGCTCGCTCGCGGCGGTGCTG
AACCGCCGGGCGCCGCTCACCGTCCGCGCGAACGCGCTCGCCGGCGATCGCGACGCGCTCCGGGCGGCGCTCGCCGCCGA
GGGCGTGCCGGCGGAGCCGACCCGGTTCTCGCCCTGGGGGCTCACGCTCGACGGCCACCAGAACGCGTTCGCGCTGGAGG
CGTTCCGCACCGGCGGGTTCGAGATCCAGGACGAGGGCAGCCAGCTCATCGCGCTCGCCTGCGGCGCGCGCCCGGGCCAG
GTGGTGGTGGACGCCTGCGCCGGCGCCGGCGGCAAGTCGCTCGCGCTCGCCGCCGAGATGCACAACAAGGGCTCGCTCCA
CGCGCTCGACAGCGACGCGGGCCGGCTCGAGGACGCGCGCCGCCGCGCCCGCCGCGCCCACGTGCACAACCTCCGCACCC
GCGTCGTCCCGGCCGGCCCCGAGGCGGAGGCGGCCGTGGCCGACCTCGCCGGCAAGGCGGACGTGGTGCTGGTGGACGCG
CCCTGCAGCGGCCTCGGCACGCTGCGCCGCAAGCCCGACGCGCGCTGGCGGCTCCAGCCCGGCGACCCGGAGCGCTTCGC
CGCGATCCAGCGGGAGCTGCTGGGCCGGTTCTCGCGCCTGGCGCGGCCCGGCGGGCGCGTGGTCTACGCCACCTGCGCCA
TGGGCCGGACCGAGAACGACGAGGTCGCCGACTACGCCGAGCGCGAGCTCGGCCTCGCGCCCGCGCCGCTGGCGCCGTTC
CTGGGCGCGGAGCGGGCCCGCGCGCTCGGCGCCGGAGAGAGCCGCTGCGCGCTCTACCCGCACCGCCACGGGACGGACGG
CTTCTTCTTCGCGGCGTTTGCGAAGCGCGCGTAG

Upstream 100 bases:

>100_bases
TGGACGGGCACGTGGCCAGCGTGCTCGAGAGCCTGTAGATTCCGCGCGCCCGCGCCGCCTCCTTCCGTGCGCGGGAGGGA
GGCGCCCGCGGGCGCACGCC

Downstream 100 bases:

>100_bases
CCGGGGACCTCGCGCATGCCGGAGCTCCCCGAGGTCGAGATCGCGGCGCGGAACCTCCGCCGCTGGGCGGAGGGCCGCCG
CGTCGAGGAGGTCGGCTGGG

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTRKPHPQRPPRNDLVDALVLEVHGLVHDQGWLADRALERVLRRERALWANERRAVAEAVYGILRAQGQLDFLLGGSPPL
ATRYAAWLVRAAGVAPAQAAARLGASPRALAGLAEADARVAAIPDPLDRFAVEASLPRWIAERLVSELGEAEARSLAAVL
NRRAPLTVRANALAGDRDALRAALAAEGVPAEPTRFSPWGLTLDGHQNAFALEAFRTGGFEIQDEGSQLIALACGARPGQ
VVVDACAGAGGKSLALAAEMHNKGSLHALDSDAGRLEDARRRARRAHVHNLRTRVVPAGPEAEAAVADLAGKADVVLVDA
PCSGLGTLRRKPDARWRLQPGDPERFAAIQRELLGRFSRLARPGGRVVYATCAMGRTENDEVADYAERELGLAPAPLAPF
LGAERARALGAGESRCALYPHRHGTDGFFFAAFAKRA

Sequences:

>Translated_437_residues
MTRKPHPQRPPRNDLVDALVLEVHGLVHDQGWLADRALERVLRRERALWANERRAVAEAVYGILRAQGQLDFLLGGSPPL
ATRYAAWLVRAAGVAPAQAAARLGASPRALAGLAEADARVAAIPDPLDRFAVEASLPRWIAERLVSELGEAEARSLAAVL
NRRAPLTVRANALAGDRDALRAALAAEGVPAEPTRFSPWGLTLDGHQNAFALEAFRTGGFEIQDEGSQLIALACGARPGQ
VVVDACAGAGGKSLALAAEMHNKGSLHALDSDAGRLEDARRRARRAHVHNLRTRVVPAGPEAEAAVADLAGKADVVLVDA
PCSGLGTLRRKPDARWRLQPGDPERFAAIQRELLGRFSRLARPGGRVVYATCAMGRTENDEVADYAERELGLAPAPLAPF
LGAERARALGAGESRCALYPHRHGTDGFFFAAFAKRA
>Mature_436_residues
TRKPHPQRPPRNDLVDALVLEVHGLVHDQGWLADRALERVLRRERALWANERRAVAEAVYGILRAQGQLDFLLGGSPPLA
TRYAAWLVRAAGVAPAQAAARLGASPRALAGLAEADARVAAIPDPLDRFAVEASLPRWIAERLVSELGEAEARSLAAVLN
RRAPLTVRANALAGDRDALRAALAAEGVPAEPTRFSPWGLTLDGHQNAFALEAFRTGGFEIQDEGSQLIALACGARPGQV
VVDACAGAGGKSLALAAEMHNKGSLHALDSDAGRLEDARRRARRAHVHNLRTRVVPAGPEAEAAVADLAGKADVVLVDAP
CSGLGTLRRKPDARWRLQPGDPERFAAIQRELLGRFSRLARPGGRVVYATCAMGRTENDEVADYAERELGLAPAPLAPFL
GAERARALGAGESRCALYPHRHGTDGFFFAAFAKRA

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=283, Percent_Identity=30.7420494699647, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI76150623, Length=283, Percent_Identity=30.7420494699647, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI32698918, Length=202, Percent_Identity=29.7029702970297, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI2367212, Length=309, Percent_Identity=27.831715210356, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081985, Length=224, Percent_Identity=31.6964285714286, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17536757, Length=286, Percent_Identity=30.4195804195804, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6324268, Length=313, Percent_Identity=26.8370607028754, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6319447, Length=273, Percent_Identity=24.9084249084249, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI22024126, Length=313, Percent_Identity=28.1150159744409, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21355201, Length=190, Percent_Identity=28.4210526315789, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24668781, Length=227, Percent_Identity=32.15859030837, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356513, Length=222, Percent_Identity=31.981981981982, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46649; Mature: 46517

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKPHPQRPPRNDLVDALVLEVHGLVHDQGWLADRALERVLRRERALWANERRAVAEAV
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGILRAQGQLDFLLGGSPPLATRYAAWLVRAAGVAPAQAAARLGASPRALAGLAEADARV
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCEE
AAIPDPLDRFAVEASLPRWIAERLVSELGEAEARSLAAVLNRRAPLTVRANALAGDRDAL
EECCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
RAALAAEGVPAEPTRFSPWGLTLDGHQNAFALEAFRTGGFEIQDEGSQLIALACGARPGQ
HHHHHHCCCCCCCCCCCCCCEEECCCCCEEEEEHHHCCCEEEECCCCEEEEEEECCCCCC
VVVDACAGAGGKSLALAAEMHNKGSLHALDSDAGRLEDARRRARRAHVHNLRTRVVPAGP
EEEEECCCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCC
EAEAAVADLAGKADVVLVDAPCSGLGTLRRKPDARWRLQPGDPERFAAIQRELLGRFSRL
CHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHH
ARPGGRVVYATCAMGRTENDEVADYAERELGLAPAPLAPFLGAERARALGAGESRCALYP
CCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHCHHHHHHHCCCCCCEEECC
HRHGTDGFFFAAFAKRA
CCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TRKPHPQRPPRNDLVDALVLEVHGLVHDQGWLADRALERVLRRERALWANERRAVAEAV
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGILRAQGQLDFLLGGSPPLATRYAAWLVRAAGVAPAQAAARLGASPRALAGLAEADARV
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCEE
AAIPDPLDRFAVEASLPRWIAERLVSELGEAEARSLAAVLNRRAPLTVRANALAGDRDAL
EECCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
RAALAAEGVPAEPTRFSPWGLTLDGHQNAFALEAFRTGGFEIQDEGSQLIALACGARPGQ
HHHHHHCCCCCCCCCCCCCCEEECCCCCEEEEEHHHCCCEEEECCCCEEEEEEECCCCCC
VVVDACAGAGGKSLALAAEMHNKGSLHALDSDAGRLEDARRRARRAHVHNLRTRVVPAGP
EEEEECCCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCC
EAEAAVADLAGKADVVLVDAPCSGLGTLRRKPDARWRLQPGDPERFAAIQRELLGRFSRL
CHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHH
ARPGGRVVYATCAMGRTENDEVADYAERELGLAPAPLAPFLGAERARALGAGESRCALYP
CCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHCHHHHHHHCCCCCCEEECC
HRHGTDGFFFAAFAKRA
CCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]