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The map label for this gene is aroB [H]

Identifier: 220915331

GI number: 220915331

Start: 229450

End: 230604

Strand: Direct

Name: aroB [H]

Synonym: A2cp1_0210

Alternate gene names: 220915331

Gene position: 229450-230604 (Clockwise)

Preceding gene: 220915330

Following gene: 220915332

Centisome position: 4.56

GC content: 78.7

Gene sequence:

>1155_bases
ATGAGCCGGACCCGCAAGCCCGCCGCGGCCGAGGAGGCCGGCGCCGCGGTCACCGAGATCATCCCGGCGCGGCAGGGCGA
CCACGCCTACGAGGTGCGCGTCGGTGCCGGCGCGGCGGCGGCGCTGCCCGCGCTCGCCGACGAGCACGACGCGGTGGCGC
TCGTCTCCTGCCGCCGGGTGCTCTCGATCCCCTTCGGAAAGGACGTGCTCGCCCGCCTGCGGCGGGAGGCGCCGCTCGCG
CTCGTGCACGCGCTCCCCGACGGCGAGGCAGGCAAGACGCTCGCCGAGCTGGAGCGGGCCGCGGCGAAGCTGCTCCGCGC
CGGCGCCACGCGGCGGACGCTGGTGGTGGCGCTGGGCGGCGGCGCGGTGAGCGACGCGGCCGGCTTCCTCGCCGCGACGT
ACATGCGCGGCGTGCCCTGGGTGGCGGTGCCCACCACGCTGCTCGCCATGGTGGACGCCGCCATCGGCGGCAAGACCGCG
GTGAACCTGCCGGCCGCGAAGAACGCGGTGGGCGCGTTCCACCCGCCCGACGCGGTGCTGGCGGATCCCGCCGCGCTCCG
CACCCTGCCGCGGCGCGAGCTCGCGAGCGGCCTCGGCGAGGTGCTGAAGTACGGGGCGCTCCAGCCGGCGCTGCTCGACG
CGTTCGCGGCGCTCGGCGCCGCCGCGCCGGACCCGGCGGTGATCGCCACCTGCGCCCGCATGAAGGTGGACGTGGTGGCG
GAGGATCCCACCGAGCACGGCCCCCGCAAGCTCCTCAACCTGGGCCACACCTTCGGCCACGGGGTGGAGGCGGCCGGGCG
GTTCTCGCGGTACACGCACGGCGAGGCGGTCGCGGTGGGGCTCGCGTTCGCGTTCCGGCTGGCGGCGCGGATGGGCCGGG
TGGACGGCGCGGCGGTGGAGCGGGTGGAGGCGGCGGTCGCCGGGGCCGGGCTGCCGGTCCGGGTCCCGCCGGCGATCGCG
CGTGCCGCCGCGCGCCTGATGGCGTACGACAAGAAGCGGGCGGCGGGCGGGCTGCGCTGGGTGCTGCCGGCGGCCGTTGA
GGACGGCTGGCGGGTGGAGTGGGACGTCGAGGCGGAGCCCGCGGCGGTCGAGGCGGCGGTGGCGGAGATCTCGGAGGCGC
GGGCGGGCGGCCGCGCCGGGCGGAGGACGCGATGA

Upstream 100 bases:

>100_bases
TCCGCGCGCGCCGGCTGCCGCTCTACCGGCGCGCCCACCTCACCGTCCACGTGGACGGGATGACGCCCGAGGCGGTGGCC
CGGCGCGTCCTGGAGTCGCT

Downstream 100 bases:

>100_bases
TCCTGGTCGTCAACGGTCCGAACCTGAACCTGCTGGGCGAGCGCGAGCCGGACGTGTACGGGCGCAGCACGCTCGGCGAC
GTGGAGCTGCTCGTCCGCGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSRTRKPAAAEEAGAAVTEIIPARQGDHAYEVRVGAGAAAALPALADEHDAVALVSCRRVLSIPFGKDVLARLRREAPLA
LVHALPDGEAGKTLAELERAAAKLLRAGATRRTLVVALGGGAVSDAAGFLAATYMRGVPWVAVPTTLLAMVDAAIGGKTA
VNLPAAKNAVGAFHPPDAVLADPAALRTLPRRELASGLGEVLKYGALQPALLDAFAALGAAAPDPAVIATCARMKVDVVA
EDPTEHGPRKLLNLGHTFGHGVEAAGRFSRYTHGEAVAVGLAFAFRLAARMGRVDGAAVERVEAAVAGAGLPVRVPPAIA
RAAARLMAYDKKRAAGGLRWVLPAAVEDGWRVEWDVEAEPAAVEAAVAEISEARAGGRAGRRTR

Sequences:

>Translated_384_residues
MSRTRKPAAAEEAGAAVTEIIPARQGDHAYEVRVGAGAAAALPALADEHDAVALVSCRRVLSIPFGKDVLARLRREAPLA
LVHALPDGEAGKTLAELERAAAKLLRAGATRRTLVVALGGGAVSDAAGFLAATYMRGVPWVAVPTTLLAMVDAAIGGKTA
VNLPAAKNAVGAFHPPDAVLADPAALRTLPRRELASGLGEVLKYGALQPALLDAFAALGAAAPDPAVIATCARMKVDVVA
EDPTEHGPRKLLNLGHTFGHGVEAAGRFSRYTHGEAVAVGLAFAFRLAARMGRVDGAAVERVEAAVAGAGLPVRVPPAIA
RAAARLMAYDKKRAAGGLRWVLPAAVEDGWRVEWDVEAEPAAVEAAVAEISEARAGGRAGRRTR
>Mature_383_residues
SRTRKPAAAEEAGAAVTEIIPARQGDHAYEVRVGAGAAAALPALADEHDAVALVSCRRVLSIPFGKDVLARLRREAPLAL
VHALPDGEAGKTLAELERAAAKLLRAGATRRTLVVALGGGAVSDAAGFLAATYMRGVPWVAVPTTLLAMVDAAIGGKTAV
NLPAAKNAVGAFHPPDAVLADPAALRTLPRRELASGLGEVLKYGALQPALLDAFAALGAAAPDPAVIATCARMKVDVVAE
DPTEHGPRKLLNLGHTFGHGVEAAGRFSRYTHGEAVAVGLAFAFRLAARMGRVDGAAVERVEAAVAGAGLPVRVPPAIAR
AAARLMAYDKKRAAGGLRWVLPAAVEDGWRVEWDVEAEPAAVEAAVAEISEARAGGRAGRRTR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=271, Percent_Identity=46.8634686346863, Blast_Score=206, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6320332, Length=290, Percent_Identity=32.4137931034483, Blast_Score=143, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39474; Mature: 39343

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTRKPAAAEEAGAAVTEIIPARQGDHAYEVRVGAGAAAALPALADEHDAVALVSCRRV
CCCCCCCCCHHHHCCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHH
LSIPFGKDVLARLRREAPLALVHALPDGEAGKTLAELERAAAKLLRAGATRRTLVVALGG
HCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GAVSDAAGFLAATYMRGVPWVAVPTTLLAMVDAAIGGKTAVNLPAAKNAVGAFHPPDAVL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHH
ADPAALRTLPRRELASGLGEVLKYGALQPALLDAFAALGAAAPDPAVIATCARMKVDVVA
CCCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEE
EDPTEHGPRKLLNLGHTFGHGVEAAGRFSRYTHGEAVAVGLAFAFRLAARMGRVDGAAVE
CCCCCCCHHHHHHHCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
RVEAAVAGAGLPVRVPPAIARAAARLMAYDKKRAAGGLRWVLPAAVEDGWRVEWDVEAEP
HHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCCCCEEEEECCCCC
AAVEAAVAEISEARAGGRAGRRTR
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SRTRKPAAAEEAGAAVTEIIPARQGDHAYEVRVGAGAAAALPALADEHDAVALVSCRRV
CCCCCCCCHHHHCCHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHH
LSIPFGKDVLARLRREAPLALVHALPDGEAGKTLAELERAAAKLLRAGATRRTLVVALGG
HCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GAVSDAAGFLAATYMRGVPWVAVPTTLLAMVDAAIGGKTAVNLPAAKNAVGAFHPPDAVL
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHH
ADPAALRTLPRRELASGLGEVLKYGALQPALLDAFAALGAAAPDPAVIATCARMKVDVVA
CCCHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHEEEEEE
EDPTEHGPRKLLNLGHTFGHGVEAAGRFSRYTHGEAVAVGLAFAFRLAARMGRVDGAAVE
CCCCCCCHHHHHHHCCHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
RVEAAVAGAGLPVRVPPAIARAAARLMAYDKKRAAGGLRWVLPAAVEDGWRVEWDVEAEP
HHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCCCCEEEEECCCCC
AAVEAAVAEISEARAGGRAGRRTR
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA