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The map label for this gene is accR [H]

Identifier: 220915049

GI number: 220915049

Start: 426138

End: 426929

Strand: Reverse

Name: accR [H]

Synonym: Mnod_8218

Alternate gene names: 220915049

Gene position: 426929-426138 (Counterclockwise)

Preceding gene: 220915062

Following gene: 220915048

Centisome position: 93.2

GC content: 68.06

Gene sequence:

>792_bases
ATGGAGGGACCGACCTTGCTGCGCGACGTGCGGCTGAATGGGATCGTCGATGCTCTACGCGACGGAAGGGTCCGCTCGAC
CGCGGAGCTGGCCCTTCAGTTCGGCGTCTCGGAGATGACCCTGCGGCGCGACCTCGACCACCTCGGCCGACGCGGCCTCG
TCCGGCGCGTGCACGGCGGCGCCAGAGCGGCCGCCGGCGCCGATCCGGGGTACCACCGACGTGCCGAGGAGAATGCGGCC
GCGAAGCACCGAGTCGGCCAAGCCGCAGCCCAGCTCGTGACACCGGGATCCTGCGTCTACCTTGACGCGGGGACGACGGC
GCGGGAGGTCGGCCGCGCGATCGCGGAGCGGGCGCGCGCAGAAGGGCTGACGGCCCGGATCGTGACGCATGCCGTGAACA
TCGGCGCGGAGCTCGCCGGGATCGTCGGCCTCTCCGTTCATCAGCTCGGTGGCGAGGTCGATCCCGGCACCCTGGCGGCG
ACCGGCCCCGCGCTCGTCACCGAGCTACGCGGCCTCAACTTCGACCTCTACTTCATGGGTGTCACCGGCATTGATCCAGA
GCGCGGTATGACGAACAGCACCCCGGTTGGGCTCGAGGTGAAGCGAGCGGCCATGAGCCGGGCTCGCGAGACCTGGGTGG
TAGCGGATGTTAGCAAATGGCGCCAAGTCAGCGCCTACTACATCGCCTCGATGGACGCGATCACGGGGCTTGTAACCGAT
GCGGCACAAAACAGCAGGCCGCACTTGGAGATTGAGCGGGCTTCGCTAAAGCTCAAAGTCCTATCATCCTAG

Upstream 100 bases:

>100_bases
ATAACGCTGATCGGCCAGACGTTGTCAACCCTCCGATCGCCCAGGGCGGTGGAAGGACGGCCCGGGACGTGAGATGAGGC
TATCGGCCGCGATCGGCCGC

Downstream 100 bases:

>100_bases
AGCGATATCCGATAGGTCGCGCTATAGGTGGCGAAACAGTTGCGTCATTCGGCTGGGCAAAAGCGGGTCAACACCTGTCC
GTTGAAATGCCTAGAGGTTC

Product: transcriptional regulator, DeoR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MEGPTLLRDVRLNGIVDALRDGRVRSTAELALQFGVSEMTLRRDLDHLGRRGLVRRVHGGARAAAGADPGYHRRAEENAA
AKHRVGQAAAQLVTPGSCVYLDAGTTAREVGRAIAERARAEGLTARIVTHAVNIGAELAGIVGLSVHQLGGEVDPGTLAA
TGPALVTELRGLNFDLYFMGVTGIDPERGMTNSTPVGLEVKRAAMSRARETWVVADVSKWRQVSAYYIASMDAITGLVTD
AAQNSRPHLEIERASLKLKVLSS

Sequences:

>Translated_263_residues
MEGPTLLRDVRLNGIVDALRDGRVRSTAELALQFGVSEMTLRRDLDHLGRRGLVRRVHGGARAAAGADPGYHRRAEENAA
AKHRVGQAAAQLVTPGSCVYLDAGTTAREVGRAIAERARAEGLTARIVTHAVNIGAELAGIVGLSVHQLGGEVDPGTLAA
TGPALVTELRGLNFDLYFMGVTGIDPERGMTNSTPVGLEVKRAAMSRARETWVVADVSKWRQVSAYYIASMDAITGLVTD
AAQNSRPHLEIERASLKLKVLSS
>Mature_263_residues
MEGPTLLRDVRLNGIVDALRDGRVRSTAELALQFGVSEMTLRRDLDHLGRRGLVRRVHGGARAAAGADPGYHRRAEENAA
AKHRVGQAAAQLVTPGSCVYLDAGTTAREVGRAIAERARAEGLTARIVTHAVNIGAELAGIVGLSVHQLGGEVDPGTLAA
TGPALVTELRGLNFDLYFMGVTGIDPERGMTNSTPVGLEVKRAAMSRARETWVVADVSKWRQVSAYYIASMDAITGLVTD
AAQNSRPHLEIERASLKLKVLSS

Specific function: Represses opine catabolism and conjugal transfer of the nopaline Ti plasmid pTiC58 [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=235, Percent_Identity=27.6595744680851, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI226510968, Length=228, Percent_Identity=30.7017543859649, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789519, Length=234, Percent_Identity=28.2051282051282, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789170, Length=241, Percent_Identity=25.3112033195021, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787540, Length=251, Percent_Identity=26.6932270916335, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790753, Length=237, Percent_Identity=24.8945147679325, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789059, Length=232, Percent_Identity=28.0172413793103, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082344, Length=213, Percent_Identity=26.7605633802817, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788069, Length=235, Percent_Identity=24.2553191489362, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28006; Mature: 28006

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGPTLLRDVRLNGIVDALRDGRVRSTAELALQFGVSEMTLRRDLDHLGRRGLVRRVHGG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC
ARAAAGADPGYHRRAEENAAAKHRVGQAAAQLVTPGSCVYLDAGTTAREVGRAIAERARA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
EGLTARIVTHAVNIGAELAGIVGLSVHQLGGEVDPGTLAATGPALVTELRGLNFDLYFMG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHCCCCEEEEEEE
VTGIDPERGMTNSTPVGLEVKRAAMSRARETWVVADVSKWRQVSAYYIASMDAITGLVTD
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AAQNSRPHLEIERASLKLKVLSS
HHCCCCCCEEEEECEEEEEEECC
>Mature Secondary Structure
MEGPTLLRDVRLNGIVDALRDGRVRSTAELALQFGVSEMTLRRDLDHLGRRGLVRRVHGG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCC
ARAAAGADPGYHRRAEENAAAKHRVGQAAAQLVTPGSCVYLDAGTTAREVGRAIAERARA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
EGLTARIVTHAVNIGAELAGIVGLSVHQLGGEVDPGTLAATGPALVTELRGLNFDLYFMG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHCCCCEEEEEEE
VTGIDPERGMTNSTPVGLEVKRAAMSRARETWVVADVSKWRQVSAYYIASMDAITGLVTD
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
AAQNSRPHLEIERASLKLKVLSS
HHCCCCCCEEEEECEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1731335; 9393724; 11743193; 11743194 [H]