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The map label for this gene is frpA [H]

Identifier: 220914990

GI number: 220914990

Start: 365168

End: 366550

Strand: Reverse

Name: frpA [H]

Synonym: Mnod_8151

Alternate gene names: 220914990

Gene position: 366550-365168 (Counterclockwise)

Preceding gene: 220914992

Following gene: 220914989

Centisome position: 80.02

GC content: 64.71

Gene sequence:

>1383_bases
ATGTCCACAGCATTCCGCGTAATTGTCGAAGGCAGCCAGGAAGTACCCCCGAATGGCTCGACCGCAAGGGGCACCGGGAC
GGTCATCTTTGACACTACGGCGCAAGCCGCGAGCTATTCGTTTCGCATCACAGGCGTTGATTATGGCCCGGCTACGGGTG
GTCCGGCTCAGACCGAAACGCCCCTTGATGATGCCACCAGCACGCATTTCCACAACCAAGTGCGAGGCCAAAACGGGCCC
GTTGTCTTCGGGCAGATCAACCCGGCCCAGGACAATGACGATCTTGCGATCGTGCCGAATGCGGATGGCTCCTGGACCGT
GAGCGGTCGCTGGGAAACAACGGACCCGGCAAATGTCTCGATTGCCAACTTCTCCACCACGCTTGGTTCGGCCACGGTGG
GGTCAGAGGTTCCGCTTTATTTCAACGTCCATACAAATCAGTTCCCCGCAGGCGAGATCCGAGGGCAATTGGTCGCGATT
GCTGATGACAACAACAACACTGTTGTTGGCACGGCAGATGATGAATTGCTTCCTGGGCTCGGCGGCGATGACATCGTCCT
TGGCCTCGTGGGGAACGATACGATCCAGGGGGGCGATGGCAACGACTTCGTCTCGGGCGGCTTCGGCGCCGACAGCGTCT
CGGGTGATGCCGGCAACGACCTCGTCTTCGGTGACGATGACGATGACGTCGCGGATGGCGGGGAGGGCAACGACCGCGTC
CATGGCGGCACCGGCGCCGATCGCGTCTTCGGCGCGGCCGGTGACGATCAGGTCTACGGCGAATGGGGCAACGACTTCGT
CAGCGGCGGCGAGGGCCACGACTTCGTCTCGGGTGGCTTCGGCAACGACGAGGTGAATGGGGATGCCGGCAACGACCTGC
TCTTCGGCGATGACGGCGACGATGCGGTCTCGGGCGGGGAGGGCAACGACCGCGTCTATGGCGGCACCGGCAATGACCTG
GTGAGCGGGGATGCAGGGGCCGATCAGTTGTTTGGCGAGCAGGGCGAGGACGTGCTGCTGGGCGGGGCGGGCTCGGACTA
CCTATCGGGCGGGGCGGGCGCCGACCAGCTGTTCGGGGGCGAGGGCGCGGACCTGTTGTTCGGCAATGCGGGCGCCGACG
CGCTGACGGGGGGCCTTGGGTCCGACGCATTCGCGTTCGGGCGCGGGGACGGTCAGGACGTGATCCGGGACTTCGTGACC
GGGGGCGCGGAGCGGGACGTGATCGCGTTCAACAACGGCGCGCTCGGGTCGTTTGCGGCGGTGCAGGCGGCGCTGCGGCA
GGAGGGCTCGGATGCGGTGATCGCCTACGGCACGGGCGACACGATCACGCTACAGAACGTTCAGGCCTCGAGTCTCACAG
CCGACAACTTCAGCTTCAGTTGA

Upstream 100 bases:

>100_bases
ATGATGGGTGCGGAACCGTACAGTTCCATGTGTGCCCCTGCGGGGGCAGTACCCTAGTGCTACTCGCCCTGCAGGTGCTG
AACACGGACAGGAGGAACTC

Downstream 100 bases:

>100_bases
GGTCTGAAGGCCGGTCCTGCTGGACGCTGGAAGGGATGTGACGGCGAATGCCCGTTCACAGGAGGGGTCGATGGCTGAGA
TCCATCATGAAATCAAAGTG

Product: CHRD domain containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSTAFRVIVEGSQEVPPNGSTARGTGTVIFDTTAQAASYSFRITGVDYGPATGGPAQTETPLDDATSTHFHNQVRGQNGP
VVFGQINPAQDNDDLAIVPNADGSWTVSGRWETTDPANVSIANFSTTLGSATVGSEVPLYFNVHTNQFPAGEIRGQLVAI
ADDNNNTVVGTADDELLPGLGGDDIVLGLVGNDTIQGGDGNDFVSGGFGADSVSGDAGNDLVFGDDDDDVADGGEGNDRV
HGGTGADRVFGAAGDDQVYGEWGNDFVSGGEGHDFVSGGFGNDEVNGDAGNDLLFGDDGDDAVSGGEGNDRVYGGTGNDL
VSGDAGADQLFGEQGEDVLLGGAGSDYLSGGAGADQLFGGEGADLLFGNAGADALTGGLGSDAFAFGRGDGQDVIRDFVT
GGAERDVIAFNNGALGSFAAVQAALRQEGSDAVIAYGTGDTITLQNVQASSLTADNFSFS

Sequences:

>Translated_460_residues
MSTAFRVIVEGSQEVPPNGSTARGTGTVIFDTTAQAASYSFRITGVDYGPATGGPAQTETPLDDATSTHFHNQVRGQNGP
VVFGQINPAQDNDDLAIVPNADGSWTVSGRWETTDPANVSIANFSTTLGSATVGSEVPLYFNVHTNQFPAGEIRGQLVAI
ADDNNNTVVGTADDELLPGLGGDDIVLGLVGNDTIQGGDGNDFVSGGFGADSVSGDAGNDLVFGDDDDDVADGGEGNDRV
HGGTGADRVFGAAGDDQVYGEWGNDFVSGGEGHDFVSGGFGNDEVNGDAGNDLLFGDDGDDAVSGGEGNDRVYGGTGNDL
VSGDAGADQLFGEQGEDVLLGGAGSDYLSGGAGADQLFGGEGADLLFGNAGADALTGGLGSDAFAFGRGDGQDVIRDFVT
GGAERDVIAFNNGALGSFAAVQAALRQEGSDAVIAYGTGDTITLQNVQASSLTADNFSFS
>Mature_459_residues
STAFRVIVEGSQEVPPNGSTARGTGTVIFDTTAQAASYSFRITGVDYGPATGGPAQTETPLDDATSTHFHNQVRGQNGPV
VFGQINPAQDNDDLAIVPNADGSWTVSGRWETTDPANVSIANFSTTLGSATVGSEVPLYFNVHTNQFPAGEIRGQLVAIA
DDNNNTVVGTADDELLPGLGGDDIVLGLVGNDTIQGGDGNDFVSGGFGADSVSGDAGNDLVFGDDDDDVADGGEGNDRVH
GGTGADRVFGAAGDDQVYGEWGNDFVSGGEGHDFVSGGFGNDEVNGDAGNDLLFGDDGDDAVSGGEGNDRVYGGTGNDLV
SGDAGADQLFGEQGEDVLLGGAGSDYLSGGAGADQLFGGEGADLLFGNAGADALTGGLGSDAFAFGRGDGQDVIRDFVTG
GAERDVIAFNNGALGSFAAVQAALRQEGSDAVIAYGTGDTITLQNVQASSLTADNFSFS

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 12 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 46238; Mature: 46107

Theoretical pI: Translated: 3.47; Mature: 3.47

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAFRVIVEGSQEVPPNGSTARGTGTVIFDTTAQAASYSFRITGVDYGPATGGPAQTET
CCCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCC
PLDDATSTHFHNQVRGQNGPVVFGQINPAQDNDDLAIVPNADGSWTVSGRWETTDPANVS
CCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEECCEECCCCCCCEE
IANFSTTLGSATVGSEVPLYFNVHTNQFPAGEIRGQLVAIADDNNNTVVGTADDELLPGL
EEECEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCEEEECCCHHHCCCC
GGDDIVLGLVGNDTIQGGDGNDFVSGGFGADSVSGDAGNDLVFGDDDDDVADGGEGNDRV
CCCCEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEE
HGGTGADRVFGAAGDDQVYGEWGNDFVSGGEGHDFVSGGFGNDEVNGDAGNDLLFGDDGD
ECCCCHHHEECCCCCCCEECCCCCHHCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCC
DAVSGGEGNDRVYGGTGNDLVSGDAGADQLFGEQGEDVLLGGAGSDYLSGGAGADQLFGG
CCCCCCCCCCEEECCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCHHCCCCCCCHHHCCC
EGADLLFGNAGADALTGGLGSDAFAFGRGDGQDVIRDFVTGGAERDVIAFNNGALGSFAA
CCCEEEEECCCCHHHCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCEEEECCCCCCHHHH
VQAALRQEGSDAVIAYGTGDTITLQNVQASSLTADNFSFS
HHHHHHCCCCCEEEEECCCCEEEEECCCCCEEECCCCCCC
>Mature Secondary Structure 
STAFRVIVEGSQEVPPNGSTARGTGTVIFDTTAQAASYSFRITGVDYGPATGGPAQTET
CCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCC
PLDDATSTHFHNQVRGQNGPVVFGQINPAQDNDDLAIVPNADGSWTVSGRWETTDPANVS
CCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEECCEECCCCCCCEE
IANFSTTLGSATVGSEVPLYFNVHTNQFPAGEIRGQLVAIADDNNNTVVGTADDELLPGL
EEECEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCEEEECCCHHHCCCC
GGDDIVLGLVGNDTIQGGDGNDFVSGGFGADSVSGDAGNDLVFGDDDDDVADGGEGNDRV
CCCCEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEE
HGGTGADRVFGAAGDDQVYGEWGNDFVSGGEGHDFVSGGFGNDEVNGDAGNDLLFGDDGD
ECCCCHHHEECCCCCCCEECCCCCHHCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCC
DAVSGGEGNDRVYGGTGNDLVSGDAGADQLFGEQGEDVLLGGAGSDYLSGGAGADQLFGG
CCCCCCCCCCEEECCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCHHCCCCCCCHHHCCC
EGADLLFGNAGADALTGGLGSDAFAFGRGDGQDVIRDFVTGGAERDVIAFNNGALGSFAA
CCCEEEEECCCCHHHCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCEEEECCCCCCHHHH
VQAALRQEGSDAVIAYGTGDTITLQNVQASSLTADNFSFS
HHHHHHCCCCCEEEEECCCCEEEEECCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]