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The map label for this gene is moxF [H]

Identifier: 220914893

GI number: 220914893

Start: 264401

End: 266290

Strand: Reverse

Name: moxF [H]

Synonym: Mnod_8040

Alternate gene names: 220914893

Gene position: 266290-264401 (Counterclockwise)

Preceding gene: 220914894

Following gene: 220914892

Centisome position: 58.13

GC content: 64.71

Gene sequence:

>1890_bases
ATGCTGGGTAAGATTGTGGTTCGTTGTCGGACGGGGGTGTCAGTGGCTGCCCTGGCGGCGCTGCTGCCGCTCGCCGGCCC
TTCGGCGCTCGCGAACGACAAGCTCGTCGAGCTGTCGAAGAGCGACGGAAACTGGGTGATGCCCGGGAAGAACTACGACT
CCGACAACTACAGCAAGCTGAAGCAGATCAACGCCGAGAACGTCAAGAACCTGAAGGTGTCGTGGCAGTTCTCGACCGGA
CTGCTGAACGGCCACGAAGGCGCGCCGCTCGTCGTCGACGGCACGATGTACGTGCACACCTCGTTCCCGAACAACACCTT
CGCGCTCGGCCTGGACGATCCGGGCAAGATCCTGTGGCAGGACAAGCCCAAGCAGAACCCGGCGGCGCGCTCGGTGGCCT
GCTGCGACCTCGTCAACCGCGGCCTCGCCTATTGGCCGGGCGACGGCAAGACCCCGTCCCTGATCCTCAAGACGCTGCTC
GACGGCCACGTCGTGGCCCTCAACGCCCAGACGGGCGAGACCGTCTGGAAGATCGAGAATTCCGATATCCGGGTCGGCTC
GACGCTCACCATCGCCCCCTATGTGGTCAAGGACAAGGTGATCATCGGCTCCTCGGGCGCCGAACTCGGCGTGCGCGGCT
ATCTCACCGCCTACGACGTCCGCACGGGCGAGCAGAAGTGGCGCGCCTACGCCACGGGTCCGGATTCCGACCTGCTGCTG
GCCAAGGACTTCAACATCCACAACGCCCATTACGGCCAGAAGGGGCTCGGCACCTCGACCTGGGAGGGCGACGCCTGGAA
GATCGGCGGCGGCACCAACTGGGGCTGGTACGCCTATGACCCCGGCACCAACCTGATCTATTTCGGCACCGGCAACCCGG
CGCCCTGGAACGAGACCATGCGTCCGGGCGACAACAAGTGGACGATGACCATCTTCGCCCGCGACGTCGATACCGGCGAG
GCCAAGTTCGGCTACCAGAAGACGCCGCACGACGAGTGGGATTACGCGGGCGTCAACGTGATGATGCTCTCGACCCAGAA
GGACCGGAGCGGCAAGGAGCGCAAGCTGCTGACGCATCCGGACCGCAACGGCATCGTCTACACCCTCGACCGCACCAACG
GCGACCTGATCTCCGCCCACAAGATCGACGACACCGTCAACGTCTTCAAGACCGTCGACCTCAAGTCGGGCCTGCCGGTG
CGCGATCCGGAATACGGCACCCGGATGGACCATCTCGCCAAGGACATCTGTCCCTCCGCGATGGGCTATCACAACCAGGG
CCACGATTCCTATGATCCGGAGCGCAAGCTCTTCTACATGGGCATCAACCACATCTGCATGGATTGGGAGCCCTTCATGC
TGCCCTACCGCGCCGGGCAGTTCTTCGTCGGCGCGACGCTCAACATGTATCCGGGCCCGAAGGGCGACCGCCAGAACGCC
GAGGGCCTCGGCCAGATCAAGGCCTACGACGCCATCACCGGCAAGTTCAAATGGGAGAAGATGGAGCGTTTCGCGGTCTG
GGGCGGAACGCTCGCCACCGCCGGCAACGTGGTCTTCTACGGAACCCTGGACGGCTTCATCAAGGCGCGCCACTCCGACA
CGGGTGAACTGCTCTGGAAGGCGAAGCTGCCCTCGGGCGCGATCGGCTATCCCGTTACCTACACCCACAAGGGCACCCAG
TACGTGGCGATCTACTACGGCGTCGGCGGTTGGCCGGGCGTCGGCCTCGTCTTCGACCTGCAGGATCCGACCGCCGGCCT
CGGCGCGGTCGGCGCCTTCAAGAAGCTCGCCAACTACACCCAGATGGGCGGTGGCGTGACCGTGTTCTCCCTCGACGGCA
AGGGTCCCTACGACGACCCGAATACCGGCGAGTACGTGGCGGCCAACTGA

Upstream 100 bases:

>100_bases
TAGGAAAATACACAAACATCACGGTTCCAATGCTTCTCGATGCGTGAACAGAAACTGCTCCGCGGCTGTGTGGGCGGGGA
TATGCAGATGGGAGACGCAC

Downstream 100 bases:

>100_bases
TCAGCCAGGGCCGGGCCGTCATCGGCCCGGCCCGTCCCCTTGGGCCTGATTGTCACGGATTGAGAGCATGCTGAGATCCC
TCGTCGGCGGGCTCGCCGGC

Product: PQQ-dependent dehydrogenase, methanol/ethanol family

Products: NA

Alternate protein names: MDH large subunit alpha; MEDH [H]

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MLGKIVVRCRTGVSVAALAALLPLAGPSALANDKLVELSKSDGNWVMPGKNYDSDNYSKLKQINAENVKNLKVSWQFSTG
LLNGHEGAPLVVDGTMYVHTSFPNNTFALGLDDPGKILWQDKPKQNPAARSVACCDLVNRGLAYWPGDGKTPSLILKTLL
DGHVVALNAQTGETVWKIENSDIRVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVRTGEQKWRAYATGPDSDLLL
AKDFNIHNAHYGQKGLGTSTWEGDAWKIGGGTNWGWYAYDPGTNLIYFGTGNPAPWNETMRPGDNKWTMTIFARDVDTGE
AKFGYQKTPHDEWDYAGVNVMMLSTQKDRSGKERKLLTHPDRNGIVYTLDRTNGDLISAHKIDDTVNVFKTVDLKSGLPV
RDPEYGTRMDHLAKDICPSAMGYHNQGHDSYDPERKLFYMGINHICMDWEPFMLPYRAGQFFVGATLNMYPGPKGDRQNA
EGLGQIKAYDAITGKFKWEKMERFAVWGGTLATAGNVVFYGTLDGFIKARHSDTGELLWKAKLPSGAIGYPVTYTHKGTQ
YVAIYYGVGGWPGVGLVFDLQDPTAGLGAVGAFKKLANYTQMGGGVTVFSLDGKGPYDDPNTGEYVAAN

Sequences:

>Translated_629_residues
MLGKIVVRCRTGVSVAALAALLPLAGPSALANDKLVELSKSDGNWVMPGKNYDSDNYSKLKQINAENVKNLKVSWQFSTG
LLNGHEGAPLVVDGTMYVHTSFPNNTFALGLDDPGKILWQDKPKQNPAARSVACCDLVNRGLAYWPGDGKTPSLILKTLL
DGHVVALNAQTGETVWKIENSDIRVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVRTGEQKWRAYATGPDSDLLL
AKDFNIHNAHYGQKGLGTSTWEGDAWKIGGGTNWGWYAYDPGTNLIYFGTGNPAPWNETMRPGDNKWTMTIFARDVDTGE
AKFGYQKTPHDEWDYAGVNVMMLSTQKDRSGKERKLLTHPDRNGIVYTLDRTNGDLISAHKIDDTVNVFKTVDLKSGLPV
RDPEYGTRMDHLAKDICPSAMGYHNQGHDSYDPERKLFYMGINHICMDWEPFMLPYRAGQFFVGATLNMYPGPKGDRQNA
EGLGQIKAYDAITGKFKWEKMERFAVWGGTLATAGNVVFYGTLDGFIKARHSDTGELLWKAKLPSGAIGYPVTYTHKGTQ
YVAIYYGVGGWPGVGLVFDLQDPTAGLGAVGAFKKLANYTQMGGGVTVFSLDGKGPYDDPNTGEYVAAN
>Mature_629_residues
MLGKIVVRCRTGVSVAALAALLPLAGPSALANDKLVELSKSDGNWVMPGKNYDSDNYSKLKQINAENVKNLKVSWQFSTG
LLNGHEGAPLVVDGTMYVHTSFPNNTFALGLDDPGKILWQDKPKQNPAARSVACCDLVNRGLAYWPGDGKTPSLILKTLL
DGHVVALNAQTGETVWKIENSDIRVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVRTGEQKWRAYATGPDSDLLL
AKDFNIHNAHYGQKGLGTSTWEGDAWKIGGGTNWGWYAYDPGTNLIYFGTGNPAPWNETMRPGDNKWTMTIFARDVDTGE
AKFGYQKTPHDEWDYAGVNVMMLSTQKDRSGKERKLLTHPDRNGIVYTLDRTNGDLISAHKIDDTVNVFKTVDLKSGLPV
RDPEYGTRMDHLAKDICPSAMGYHNQGHDSYDPERKLFYMGINHICMDWEPFMLPYRAGQFFVGATLNMYPGPKGDRQNA
EGLGQIKAYDAITGKFKWEKMERFAVWGGTLATAGNVVFYGTLDGFIKARHSDTGELLWKAKLPSGAIGYPVTYTHKGTQ
YVAIYYGVGGWPGVGLVFDLQDPTAGLGAVGAFKKLANYTQMGGGVTVFSLDGKGPYDDPNTGEYVAAN

Specific function: Catalyzes the oxidation of primary alcohols including methanol [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side. Note=Periplasmic, but associated with inner membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=642, Percent_Identity=25.3894080996885, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.7 [H]

Molecular weight: Translated: 68798; Mature: 68798

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00363 BACTERIAL_PQQ_1 ; PS00364 BACTERIAL_PQQ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGKIVVRCRTGVSVAALAALLPLAGPSALANDKLVELSKSDGNWVMPGKNYDSDNYSKL
CCCEEEEEEECCCHHHHHHHHHHCCCCCHHCCCCEEEEECCCCCEECCCCCCCCCCHHHH
KQINAENVKNLKVSWQFSTGLLNGHEGAPLVVDGTMYVHTSFPNNTFALGLDDPGKILWQ
HHCCCCCCEEEEEEEEEECCCCCCCCCCCEEEECEEEEEEECCCCEEEEECCCCCCEEEC
DKPKQNPAARSVACCDLVNRGLAYWPGDGKTPSLILKTLLDGHVVALNAQTGETVWKIEN
CCCCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEEC
SDIRVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVRTGEQKWRAYATGPDSDLLL
CCEEECCEEEEEEEEEEEEEEEECCCCCCCEEEEEEEEEECCCHHHEEEEECCCCCCEEE
AKDFNIHNAHYGQKGLGTSTWEGDAWKIGGGTNWGWYAYDPGTNLIYFGTGNPAPWNETM
EECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEECCCCCEEEEECCCCCCCCCCC
RPGDNKWTMTIFARDVDTGEAKFGYQKTPHDEWDYAGVNVMMLSTQKDRSGKERKLLTHP
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEECC
DRNGIVYTLDRTNGDLISAHKIDDTVNVFKTVDLKSGLPVRDPEYGTRMDHLAKDICPSA
CCCCEEEEEECCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCHHH
MGYHNQGHDSYDPERKLFYMGINHICMDWEPFMLPYRAGQFFVGATLNMYPGPKGDRQNA
HCCCCCCCCCCCCCCEEEEEECCEEEECCCCEEEEEECCCEEEEEEEEECCCCCCCCCCC
EGLGQIKAYDAITGKFKWEKMERFAVWGGTLATAGNVVFYGTLDGFIKARHSDTGELLWK
CCCCCEEEEEEECCCEEHHHHEEEEEECCCEECCCCEEEEECCCCEEEECCCCCCEEEEE
AKLPSGAIGYPVTYTHKGTQYVAIYYGVGGWPGVGLVFDLQDPTAGLGAVGAFKKLANYT
EECCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHH
QMGGGVTVFSLDGKGPYDDPNTGEYVAAN
HCCCCEEEEEECCCCCCCCCCCCCEEECC
>Mature Secondary Structure
MLGKIVVRCRTGVSVAALAALLPLAGPSALANDKLVELSKSDGNWVMPGKNYDSDNYSKL
CCCEEEEEEECCCHHHHHHHHHHCCCCCHHCCCCEEEEECCCCCEECCCCCCCCCCHHHH
KQINAENVKNLKVSWQFSTGLLNGHEGAPLVVDGTMYVHTSFPNNTFALGLDDPGKILWQ
HHCCCCCCEEEEEEEEEECCCCCCCCCCCEEEECEEEEEEECCCCEEEEECCCCCCEEEC
DKPKQNPAARSVACCDLVNRGLAYWPGDGKTPSLILKTLLDGHVVALNAQTGETVWKIEN
CCCCCCCCHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEEC
SDIRVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVRTGEQKWRAYATGPDSDLLL
CCEEECCEEEEEEEEEEEEEEEECCCCCCCEEEEEEEEEECCCHHHEEEEECCCCCCEEE
AKDFNIHNAHYGQKGLGTSTWEGDAWKIGGGTNWGWYAYDPGTNLIYFGTGNPAPWNETM
EECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEECCCCCEEEEECCCCCCCCCCC
RPGDNKWTMTIFARDVDTGEAKFGYQKTPHDEWDYAGVNVMMLSTQKDRSGKERKLLTHP
CCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEECC
DRNGIVYTLDRTNGDLISAHKIDDTVNVFKTVDLKSGLPVRDPEYGTRMDHLAKDICPSA
CCCCEEEEEECCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCHHH
MGYHNQGHDSYDPERKLFYMGINHICMDWEPFMLPYRAGQFFVGATLNMYPGPKGDRQNA
HCCCCCCCCCCCCCCEEEEEECCEEEECCCCEEEEEECCCEEEEEEEEECCCCCCCCCCC
EGLGQIKAYDAITGKFKWEKMERFAVWGGTLATAGNVVFYGTLDGFIKARHSDTGELLWK
CCCCCEEEEEEECCCEEHHHHEEEEEECCCEECCCCEEEEECCCCEEEECCCCCCEEEEE
AKLPSGAIGYPVTYTHKGTQYVAIYYGVGGWPGVGLVFDLQDPTAGLGAVGAFKKLANYT
EECCCCCCCCCEEEEECCCEEEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHH
QMGGGVTVFSLDGKGPYDDPNTGEYVAAN
HCCCCEEEEEECCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2116368; 2504152; 11761326; 7656012; 7735834; 11502173 [H]