Click here to switch to the map view.

The map label for this gene is moxX [H]

Identifier: 220914880

GI number: 220914880

Start: 254131

End: 254766

Strand: Reverse

Name: moxX [H]

Synonym: Mnod_8027

Alternate gene names: 220914880

Gene position: 254766-254131 (Counterclockwise)

Preceding gene: 220914881

Following gene: 220914879

Centisome position: 55.62

GC content: 61.16

Gene sequence:

>636_bases
ATGTCCGGGAGCGTTCTGATCATCGACGATCATCCCGTGGTCCTGCAGGGGTGCCGGGTTGTCCTGGAGGATGCCGGGCT
CGCGACGATCCACGTCGCCACCGGCGTGGAGGAGGGCTACCAGAGCTTCTACCGCAACCGGCCCGGCCTGGTGGTGGCCG
ACCTGACTTTCCAGGACAGTGGCCTCACCGGTCTCTCGCTGATCCGGCGGATCCGCGCGCTCGAACCGGCGACTCGCATC
CTCGTGTTCAGCATGCATGACGACCCGGTGATCGTCGCCCGCGCGCTGGAGGGCGGCGCGATCGGCTATCTTCTCAAAGA
TACTCCCTCGGTCGACTTTGCCACTGCCGTCGCACGGGTCCAGGCCGGCGAGCCTTACATCGATCATCGCCTCGCAATGA
AGGTGGCAATCCTCCAGAGCAGCCAGCGAGTGAGTCCGCTCTTGGCCCTCACCGGACGAGAGTTGCAAATCTTCTTGCTT
CTTTCGCGAGGTAAATCTTACGAAATGATCGCCAAATACCTCAGTCTGAGTTATAAGACGGTGGCTAATACGTGCTCCAG
CATGCGGCGCAAGCTCGGAGCCGAGAGTCTTTCTGAACTAATCCGCCTTGCAATCAGGCACCACAGCCAGAGCTGA

Upstream 100 bases:

>100_bases
GCACCAAGTACGCACCCCAGAGCCTGAAGCAGCCGTGATGATGGCCGCCACGCCAACCCGAATGCGCTCCAACCGAACAG
CGCGGCAGCGGGAGGTGAAC

Downstream 100 bases:

>100_bases
TCCCGAGTGAAAAGGTCCGATTCAAGGCACTTCAATCTGCGACATATCTAAACAGGGAGATGATTTCGTGGTGCGGCTCG
CCATAACAGTCTTGATATTT

Product: two component transcriptional regulator, LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSGSVLIIDDHPVVLQGCRVVLEDAGLATIHVATGVEEGYQSFYRNRPGLVVADLTFQDSGLTGLSLIRRIRALEPATRI
LVFSMHDDPVIVARALEGGAIGYLLKDTPSVDFATAVARVQAGEPYIDHRLAMKVAILQSSQRVSPLLALTGRELQIFLL
LSRGKSYEMIAKYLSLSYKTVANTCSSMRRKLGAESLSELIRLAIRHHSQS

Sequences:

>Translated_211_residues
MSGSVLIIDDHPVVLQGCRVVLEDAGLATIHVATGVEEGYQSFYRNRPGLVVADLTFQDSGLTGLSLIRRIRALEPATRI
LVFSMHDDPVIVARALEGGAIGYLLKDTPSVDFATAVARVQAGEPYIDHRLAMKVAILQSSQRVSPLLALTGRELQIFLL
LSRGKSYEMIAKYLSLSYKTVANTCSSMRRKLGAESLSELIRLAIRHHSQS
>Mature_210_residues
SGSVLIIDDHPVVLQGCRVVLEDAGLATIHVATGVEEGYQSFYRNRPGLVVADLTFQDSGLTGLSLIRRIRALEPATRIL
VFSMHDDPVIVARALEGGAIGYLLKDTPSVDFATAVARVQAGEPYIDHRLAMKVAILQSSQRVSPLLALTGRELQIFLLL
SRGKSYEMIAKYLSLSYKTVANTCSSMRRKLGAESLSELIRLAIRHHSQS

Specific function: Member of the two-component regulatory system moxY/moxX probably involved in the regulation of the methanol dehydrogenase expression [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=31.4009661835749, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1786747, Length=202, Percent_Identity=28.2178217821782, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788546, Length=202, Percent_Identity=30.1980198019802, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790102, Length=204, Percent_Identity=31.3725490196078, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=30.6010928961749, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1788521, Length=194, Percent_Identity=27.319587628866, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=24.5098039215686, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23061; Mature: 22930

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSVLIIDDHPVVLQGCRVVLEDAGLATIHVATGVEEGYQSFYRNRPGLVVADLTFQDS
CCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCEEEEEEEECCC
GLTGLSLIRRIRALEPATRILVFSMHDDPVIVARALEGGAIGYLLKDTPSVDFATAVARV
CCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHH
QAGEPYIDHRLAMKVAILQSSQRVSPLLALTGRELQIFLLLSRGKSYEMIAKYLSLSYKT
CCCCCHHHHHHHHHHHHHHCCCCCCHHEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHH
VANTCSSMRRKLGAESLSELIRLAIRHHSQS
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGSVLIIDDHPVVLQGCRVVLEDAGLATIHVATGVEEGYQSFYRNRPGLVVADLTFQDS
CCCEEEEECCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCEEEEEEEECCC
GLTGLSLIRRIRALEPATRILVFSMHDDPVIVARALEGGAIGYLLKDTPSVDFATAVARV
CCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHH
QAGEPYIDHRLAMKVAILQSSQRVSPLLALTGRELQIFLLLSRGKSYEMIAKYLSLSYKT
CCCCCHHHHHHHHHHHHHHCCCCCCHHEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHH
VANTCSSMRRKLGAESLSELIRLAIRHHSQS
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8392137 [H]