| Definition | Methylobacterium nodulans ORS 2060 plasmid pMNOD02, complete sequence. |
|---|---|
| Accession | NC_011887 |
| Length | 458,070 |
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The map label for this gene is msbA [H]
Identifier: 220914852
GI number: 220914852
Start: 219525
End: 220145
Strand: Reverse
Name: msbA [H]
Synonym: Mnod_7996
Alternate gene names: 220914852
Gene position: 220145-219525 (Counterclockwise)
Preceding gene: 220914853
Following gene: 220914851
Centisome position: 48.06
GC content: 71.18
Gene sequence:
>621_bases ATGAGGTGTGACCGCGATCGGGGACTGCATATCGAGGACCTGCGCAGCGATCTGGCGGGGCCTTTCGATCTCGTCGTGCC CAAGGGGCAGATCGTGACCATCGCCGGCCCGTCCGGCTCGGGAAAGAGCCTGTTCCTGCGCATGATCGCCGATCTCGACG TGAATACCGGGCGGGTCCGGCTCGACGGGCGGTGGCGCTCCGAGATGCCGGCTCCGGAGTGGCGGCGGCAGGTCCCCTAC GTCGCCGCCGAGCCAGGCTGGTGGAGCGACGCGATCGCCGATCACGTCGCGCCGGAGCACCGGGCCGCAGCCGAGGCGCT CGCCGCACGTCTCGGTGTCGGCGCACGCCCCTTCGCGGGACTGGTCGCCAACCTCTCGACCGGGGAACGTCAGCGCTTGG CCCTGGTCCGCGCCCTCGTGCGTGAGACGCCGGCCCTTCTCCTCGACGAGCCCACCGGGCCTCTCGATCCGGTTTCCACC ACGGCCGTCGAGGCGCTTCTGCGGGAGCGTGCGGCAGCCGGAGCGATCATCCTGATGGTCTCCCATGATCCCGGTCAGAG CGAGCGTCTGAGCGCACGGGCCCTGCGCATGGCGGCGCGTCGGCTGGAGGCGGTGCCATGA
Upstream 100 bases:
>100_bases CGCTCACACTGCCGTCGCAGGATGGTGCGCATCGCCGCTGTCTCGGCAAGACGGTCCGCTGTCGGTGCGAAGGCAGAGCC TCGCCGGGCCCCGACCTGCC
Downstream 100 bases:
>100_bases CCCCGATCACCCTCAGCGCCACCGACCTCGCGCTCGCGGCGTCGCTCGTCGTCCTGGATGCGGGCCTCTCGCTCGCCCTG CGCCTCAACCTCCACCGCCA
Product: ABC transporter related
Products: ADP; phosphate; thiamine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 206; Mature: 206
Protein sequence:
>206_residues MRCDRDRGLHIEDLRSDLAGPFDLVVPKGQIVTIAGPSGSGKSLFLRMIADLDVNTGRVRLDGRWRSEMPAPEWRRQVPY VAAEPGWWSDAIADHVAPEHRAAAEALAARLGVGARPFAGLVANLSTGERQRLALVRALVRETPALLLDEPTGPLDPVST TAVEALLRERAAAGAIILMVSHDPGQSERLSARALRMAARRLEAVP
Sequences:
>Translated_206_residues MRCDRDRGLHIEDLRSDLAGPFDLVVPKGQIVTIAGPSGSGKSLFLRMIADLDVNTGRVRLDGRWRSEMPAPEWRRQVPY VAAEPGWWSDAIADHVAPEHRAAAEALAARLGVGARPFAGLVANLSTGERQRLALVRALVRETPALLLDEPTGPLDPVST TAVEALLRERAAAGAIILMVSHDPGQSERLSARALRMAARRLEAVP >Mature_206_residues MRCDRDRGLHIEDLRSDLAGPFDLVVPKGQIVTIAGPSGSGKSLFLRMIADLDVNTGRVRLDGRWRSEMPAPEWRRQVPY VAAEPGWWSDAIADHVAPEHRAAAEALAARLGVGARPFAGLVANLSTGERQRLALVRALVRETPALLLDEPTGPLDPVST TAVEALLRERAAAGAIILMVSHDPGQSERLSARALRMAARRLEAVP
Specific function: Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]
COG id: COG2274
COG function: function code V; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI9961250, Length=176, Percent_Identity=32.9545454545455, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI4505771, Length=176, Percent_Identity=32.9545454545455, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI9961252, Length=176, Percent_Identity=32.9545454545455, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI255708477, Length=176, Percent_Identity=32.9545454545455, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI171184400, Length=180, Percent_Identity=32.7777777777778, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI156105685, Length=179, Percent_Identity=32.4022346368715, Blast_Score=69, Evalue=2e-12, Organism=Homo sapiens, GI9955963, Length=177, Percent_Identity=30.5084745762712, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI148612844, Length=188, Percent_Identity=32.9787234042553, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI21536378, Length=179, Percent_Identity=29.0502793296089, Blast_Score=68, Evalue=5e-12, Organism=Homo sapiens, GI42741659, Length=178, Percent_Identity=31.4606741573034, Blast_Score=68, Evalue=5e-12, Organism=Homo sapiens, GI9955966, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI45243524, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI9955968, Length=151, Percent_Identity=31.7880794701987, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI9665248, Length=177, Percent_Identity=31.638418079096, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1786253, Length=194, Percent_Identity=34.020618556701, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1787143, Length=164, Percent_Identity=33.5365853658537, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787712, Length=200, Percent_Identity=31.5, Blast_Score=77, Evalue=6e-16, Organism=Escherichia coli, GI1788450, Length=189, Percent_Identity=31.2169312169312, Blast_Score=74, Evalue=5e-15, Organism=Escherichia coli, GI1787089, Length=198, Percent_Identity=29.2929292929293, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1790534, Length=181, Percent_Identity=32.5966850828729, Blast_Score=70, Evalue=8e-14, Organism=Escherichia coli, GI1786698, Length=166, Percent_Identity=30.1204819277108, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786398, Length=184, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=6e-13, Organism=Escherichia coli, GI1787370, Length=204, Percent_Identity=26.9607843137255, Blast_Score=67, Evalue=7e-13, Organism=Escherichia coli, GI1787105, Length=184, Percent_Identity=30.9782608695652, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI87081791, Length=192, Percent_Identity=31.25, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1789873, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1786563, Length=191, Percent_Identity=30.3664921465969, Blast_Score=64, Evalue=6e-12, Organism=Escherichia coli, GI1787164, Length=178, Percent_Identity=32.5842696629214, Blast_Score=61, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17567265, Length=169, Percent_Identity=34.3195266272189, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17567269, Length=170, Percent_Identity=34.7058823529412, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193208177, Length=176, Percent_Identity=30.6818181818182, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI115535101, Length=170, Percent_Identity=34.1176470588235, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI115533592, Length=176, Percent_Identity=31.8181818181818, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17541710, Length=175, Percent_Identity=31.4285714285714, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193211017, Length=172, Percent_Identity=29.6511627906977, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193211015, Length=172, Percent_Identity=29.6511627906977, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71996809, Length=172, Percent_Identity=29.6511627906977, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI115534520, Length=152, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71996550, Length=162, Percent_Identity=30.8641975308642, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI193202349, Length=175, Percent_Identity=32, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI25146777, Length=172, Percent_Identity=26.1627906976744, Blast_Score=64, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323217, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI24653245, Length=173, Percent_Identity=34.1040462427746, Blast_Score=74, Evalue=5e-14, Organism=Drosophila melanogaster, GI281363262, Length=169, Percent_Identity=33.7278106508876, Blast_Score=74, Evalue=6e-14, Organism=Drosophila melanogaster, GI24659289, Length=194, Percent_Identity=31.4432989690722, Blast_Score=71, Evalue=4e-13, Organism=Drosophila melanogaster, GI85726357, Length=176, Percent_Identity=28.9772727272727, Blast_Score=70, Evalue=7e-13, Organism=Drosophila melanogaster, GI17136662, Length=179, Percent_Identity=30.7262569832402, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI24585091, Length=174, Percent_Identity=26.4367816091954, Blast_Score=64, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR017940 - InterPro: IPR011917 - InterPro: IPR001140 - InterPro: IPR011527 - InterPro: IPR003593 [H]
Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 22269; Mature: 22269
Theoretical pI: Translated: 8.55; Mature: 8.55
Prosite motif: PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRCDRDRGLHIEDLRSDLAGPFDLVVPKGQIVTIAGPSGSGKSLFLRMIADLDVNTGRVR CCCCCCCCCCHHHHHHHHCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEE LDGRWRSEMPAPEWRRQVPYVAAEPGWWSDAIADHVAPEHRAAAEALAARLGVGARPFAG ECCCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHH LVANLSTGERQRLALVRALVRETPALLLDEPTGPLDPVSTTAVEALLRERAAAGAIILMV HHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE SHDPGQSERLSARALRMAARRLEAVP ECCCCCHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MRCDRDRGLHIEDLRSDLAGPFDLVVPKGQIVTIAGPSGSGKSLFLRMIADLDVNTGRVR CCCCCCCCCCHHHHHHHHCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEE LDGRWRSEMPAPEWRRQVPYVAAEPGWWSDAIADHVAPEHRAAAEALAARLGVGARPFAG ECCCCCCCCCCHHHHHCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHH LVANLSTGERQRLALVRALVRETPALLLDEPTGPLDPVSTTAVEALLRERAAAGAIILMV HHHCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE SHDPGQSERLSARALRMAARRLEAVP ECCCCCHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; thiamine [Periplasm]; H2O [C]
Specific reaction: ATP + thiamine [Periplasm] + H2O = ADP + phosphate + thiamine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 11823852 [H]