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The map label for this gene is allB [H]

Identifier: 220914807

GI number: 220914807

Start: 167122

End: 168561

Strand: Reverse

Name: allB [H]

Synonym: Mnod_7944

Alternate gene names: 220914807

Gene position: 168561-167122 (Counterclockwise)

Preceding gene: 220914808

Following gene: 220914803

Centisome position: 36.8

GC content: 69.65

Gene sequence:

>1440_bases
ATGAGCACGGACTACGATCTCCTCATCCGCGGCGGCGAAGCCGTTCTCCCAGGGCGCGGGCGCACCGCGTGCGACATCGC
CGTTCGGGACGGCCGCATCGCCGCGATCCTCGCCCCCGGCGCGCCCGCAACGGCTCCGTCCGAACTCGATGCGCGCGGCC
TCGTCGTCATGCCGGGCGCCATCGACGTGCACCTTCACCTCGGCCACGGCCGCGACATTGCGCGACCCCGAGTGCCGGAG
GATGCCGCGCGCGAGAGCGCCGCGGCGGCATCGGGCGGCATCACCTGCTTCATCCCCTACCTGATGACGAGCGAGCCCTT
CTCCACGGTGCTGCCGGAGGTGATCGCGGTGACGCAGGCCGGGTCGCGGATCGACTTCAGCTATCACCCGATCATCTCGA
CGGAAGAACAGCTCGCCGAGGTGGAGCGCTGCGCCCGGGAGTTCGGCGCCCCAACCTTCAAGATCTTCATGAACAACCGC
GGCGGCGAGGGCGCGCGCCTCGGGCTGCCCGACATCGACGATGGCTTTCTCCTGCGCCTGTGCGAGGCGGCCGCGCGTGC
CGGGGGCATGGTCTGCCCTCATCCCGAAACGATCGAGCTTGCCTGGGTGACCCGGGACCGCGCCAAGGCCGCAGATCCTG
ACGGAATCGGAGGCCTCGCCACCTGGAACGCGAGTCGGCCGCCCTTCGTGGAGGCCGATGCGGTGCAGCGCGCCGGCTAT
GTCGCCAAGACGGCCGGGGCACCCCTCTACGTGGTCCACACCTCCTCGGCCGAAGCCTTGGCGGCGGGCCTGCGTCAGCG
GCAGGCAGGCGCGACTCTCTTCCTTGAGACTTGTCCGCACTACCTGACCCACGACATCGGCTGGACTGGGGGCGACCTCG
GGAAGATCAACCCGCCCCTGCGCGAGGCGGCGGATCGCGAGGCGCTTTGGGCGGGAATCCTGTCGGGCGCCATCGACACC
ATCGCGACCGATCACGTGCATCGCGGGCTCGAAGCGAAGGCGGGAGGCATCTGGGCCGCGTCGCCGGGCTGCCCCGGCCT
CGAGACCCTGCTCCCGGTGCTGCTCAGTGAAGGCTACCATGCGCGCGGTCTCTCTTTAGAGCGCGTGGTCGATCTCGTCT
CGACCAATCCGGCGCGCCTGATGGGGCTCGCGCACCGCAAGGGTGCGATCGCACCGGGGCTAGACGCGGACCTCGCCGTC
ATCGACCTCGACGCCGCCTGGACCTTCGACCGGGGAGCCGTCCTGTCGAGCGCCGGCTACTCCTTGTACGAAGGCTGGCA
GTTCAGGGGCCGCGTCGTGCACACTGCCGTCCGTGGCCACCTTGTGCTGCGGGACGGAGCGCTTCAGGACGAGAGAATTG
GCATCGGGCGTTACGTTTCACGCAGCCTTGCGACTCAACATCGATGCGCAGCGCCCTCCGGCCTGCTTCACGCCCACTGA

Upstream 100 bases:

>100_bases
GCGTGGAAGCGGCGGTCGACGAGCTCACGGCAGCTCCGAGCCTCGACGCGCTGGAGGCCGCGCTATCCAAAGCCGCATCA
CATCCCGCTCGGAGCGACGC

Downstream 100 bases:

>100_bases
ATGCCGTAGCACTCGTTCGTCTGATGCGCTTGGCTATGCTCGCCAGGGCCGAGGATGACTGTCGGACACCTGCCGAATGC
TCCCTGCAACACCGAGCCGT

Product: amidohydrolase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSTDYDLLIRGGEAVLPGRGRTACDIAVRDGRIAAILAPGAPATAPSELDARGLVVMPGAIDVHLHLGHGRDIARPRVPE
DAARESAAAASGGITCFIPYLMTSEPFSTVLPEVIAVTQAGSRIDFSYHPIISTEEQLAEVERCAREFGAPTFKIFMNNR
GGEGARLGLPDIDDGFLLRLCEAAARAGGMVCPHPETIELAWVTRDRAKAADPDGIGGLATWNASRPPFVEADAVQRAGY
VAKTAGAPLYVVHTSSAEALAAGLRQRQAGATLFLETCPHYLTHDIGWTGGDLGKINPPLREAADREALWAGILSGAIDT
IATDHVHRGLEAKAGGIWAASPGCPGLETLLPVLLSEGYHARGLSLERVVDLVSTNPARLMGLAHRKGAIAPGLDADLAV
IDLDAAWTFDRGAVLSSAGYSLYEGWQFRGRVVHTAVRGHLVLRDGALQDERIGIGRYVSRSLATQHRCAAPSGLLHAH

Sequences:

>Translated_479_residues
MSTDYDLLIRGGEAVLPGRGRTACDIAVRDGRIAAILAPGAPATAPSELDARGLVVMPGAIDVHLHLGHGRDIARPRVPE
DAARESAAAASGGITCFIPYLMTSEPFSTVLPEVIAVTQAGSRIDFSYHPIISTEEQLAEVERCAREFGAPTFKIFMNNR
GGEGARLGLPDIDDGFLLRLCEAAARAGGMVCPHPETIELAWVTRDRAKAADPDGIGGLATWNASRPPFVEADAVQRAGY
VAKTAGAPLYVVHTSSAEALAAGLRQRQAGATLFLETCPHYLTHDIGWTGGDLGKINPPLREAADREALWAGILSGAIDT
IATDHVHRGLEAKAGGIWAASPGCPGLETLLPVLLSEGYHARGLSLERVVDLVSTNPARLMGLAHRKGAIAPGLDADLAV
IDLDAAWTFDRGAVLSSAGYSLYEGWQFRGRVVHTAVRGHLVLRDGALQDERIGIGRYVSRSLATQHRCAAPSGLLHAH
>Mature_478_residues
STDYDLLIRGGEAVLPGRGRTACDIAVRDGRIAAILAPGAPATAPSELDARGLVVMPGAIDVHLHLGHGRDIARPRVPED
AARESAAAASGGITCFIPYLMTSEPFSTVLPEVIAVTQAGSRIDFSYHPIISTEEQLAEVERCAREFGAPTFKIFMNNRG
GEGARLGLPDIDDGFLLRLCEAAARAGGMVCPHPETIELAWVTRDRAKAADPDGIGGLATWNASRPPFVEADAVQRAGYV
AKTAGAPLYVVHTSSAEALAAGLRQRQAGATLFLETCPHYLTHDIGWTGGDLGKINPPLREAADREALWAGILSGAIDTI
ATDHVHRGLEAKAGGIWAASPGCPGLETLLPVLLSEGYHARGLSLERVVDLVSTNPARLMGLAHRKGAIAPGLDADLAVI
DLDAAWTFDRGAVLSSAGYSLYEGWQFRGRVVHTAVRGHLVLRDGALQDERIGIGRYVSRSLATQHRCAAPSGLLHAH

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503375, Length=479, Percent_Identity=27.5574112734864, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI19923821, Length=462, Percent_Identity=26.6233766233766, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI4503377, Length=483, Percent_Identity=27.7432712215321, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI4503379, Length=474, Percent_Identity=25.9493670886076, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4503051, Length=485, Percent_Identity=25.5670103092783, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI62422571, Length=485, Percent_Identity=25.5670103092783, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI190194363, Length=476, Percent_Identity=26.6806722689076, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI18105007, Length=409, Percent_Identity=26.4058679706601, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1786722, Length=449, Percent_Identity=30.9576837416481, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI87082175, Length=470, Percent_Identity=30.2127659574468, Blast_Score=173, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17539558, Length=478, Percent_Identity=28.2426778242678, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71989490, Length=470, Percent_Identity=25.531914893617, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193204318, Length=437, Percent_Identity=24.4851258581236, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI86575075, Length=440, Percent_Identity=25.4545454545455, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322218, Length=404, Percent_Identity=25, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI221377917, Length=474, Percent_Identity=27.8481012658228, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17137462, Length=475, Percent_Identity=26.9473684210526, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24642586, Length=405, Percent_Identity=25.4320987654321, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI18859883, Length=234, Percent_Identity=31.6239316239316, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644287, Length=312, Percent_Identity=29.4871794871795, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 50604; Mature: 50473

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDYDLLIRGGEAVLPGRGRTACDIAVRDGRIAAILAPGAPATAPSELDARGLVVMPGA
CCCCCEEEEECCCEEECCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEECCE
IDVHLHLGHGRDIARPRVPEDAARESAAAASGGITCFIPYLMTSEPFSTVLPEVIAVTQA
EEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHHHHCC
GSRIDFSYHPIISTEEQLAEVERCAREFGAPTFKIFMNNRGGEGARLGLPDIDDGFLLRL
CCEECEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHH
CEAAARAGGMVCPHPETIELAWVTRDRAKAADPDGIGGLATWNASRPPFVEADAVQRAGY
HHHHHHCCCEECCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHCCC
VAKTAGAPLYVVHTSSAEALAAGLRQRQAGATLFLETCPHYLTHDIGWTGGDLGKINPPL
EEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEHHCCHHHHHCCCCCCCCCCCCCCHH
REAADREALWAGILSGAIDTIATDHVHRGLEAKAGGIWAASPGCPGLETLLPVLLSEGYH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCC
ARGLSLERVVDLVSTNPARLMGLAHRKGAIAPGLDADLAVIDLDAAWTFDRGAVLSSAGY
CCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEECCCCCEECCCCC
SLYEGWQFRGRVVHTAVRGHLVLRDGALQDERIGIGRYVSRSLATQHRCAAPSGLLHAH
HHHCCCCCCCEEEEEEEECEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
STDYDLLIRGGEAVLPGRGRTACDIAVRDGRIAAILAPGAPATAPSELDARGLVVMPGA
CCCCEEEEECCCEEECCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCEEEECCE
IDVHLHLGHGRDIARPRVPEDAARESAAAASGGITCFIPYLMTSEPFSTVLPEVIAVTQA
EEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHHHHCC
GSRIDFSYHPIISTEEQLAEVERCAREFGAPTFKIFMNNRGGEGARLGLPDIDDGFLLRL
CCEECEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHH
CEAAARAGGMVCPHPETIELAWVTRDRAKAADPDGIGGLATWNASRPPFVEADAVQRAGY
HHHHHHCCCEECCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHCCC
VAKTAGAPLYVVHTSSAEALAAGLRQRQAGATLFLETCPHYLTHDIGWTGGDLGKINPPL
EEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEHHCCHHHHHCCCCCCCCCCCCCCHH
REAADREALWAGILSGAIDTIATDHVHRGLEAKAGGIWAASPGCPGLETLLPVLLSEGYH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCC
ARGLSLERVVDLVSTNPARLMGLAHRKGAIAPGLDADLAVIDLDAAWTFDRGAVLSSAGY
CCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEECCCCCEECCCCC
SLYEGWQFRGRVVHTAVRGHLVLRDGALQDERIGIGRYVSRSLATQHRCAAPSGLLHAH
HHHCCCCCCCEEEEEEEECEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA