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The map label for this gene is aroC

Identifier: 220905549

GI number: 220905549

Start: 2755495

End: 2756589

Strand: Direct

Name: aroC

Synonym: Ddes_2288

Alternate gene names: 220905549

Gene position: 2755495-2756589 (Clockwise)

Preceding gene: 220905548

Following gene: 220905550

Centisome position: 95.9

GC content: 65.3

Gene sequence:

>1095_bases
ATGGCCGGAAACACCTTTGGGCGCGCCTTGCGCCTGACCACCTTCGGCGAGTCCCACGGTCCCGGCCTCGGCGGTATTAT
TGACGGCTGCCCTGCCGGGCTGGAGCTGACCGAGGCCCATATCCAGGCAGAACTGGACCGCCGCAAGCCCGGCCAGGGCC
CCACAGCCACCAAGCGCAAAGAAGCTGACACCGTGCGTCTGCTTTCCGGTGTTTTCGAGGGCTGCACCACGGGAACCCCC
ATCGCCTTTTTCATCGCCAATGAAGATCAGCGTTCCCGCGACTACGGCAACCTGGCCGAAGCCTTTCGTCCCGGCCATGC
AGACTGGGCGTATTTTCAGAAATACAACGGCCTGCGCGACCACCGGGGCGGCGGGCGCTCTTCGGGCCGCGAAACCGCTG
CGCGTGTTGCCGGAGGCGTCATTGCCAAGAAGATTCTGGCGCGGCGCGGCGTGACCATTCTGGGCGGCTGCGTTGAGCTG
GGCGGTATTGCCGCACCCCTTTGGGGGCTGGACATGGACGGGGCCGCAGCGCGGCCGTATTGCGCCGCAGCACCCTCCGT
CGTCAGCCAGTGGGACGCGCTGGTGGCCGAAGCACGCAAGGCCGGGGAAACCCTGGGCGGCATTGTCCGTATTGAAGCAC
ACAACGTGCCTGCCGGTCTTGGTGAACCTGTTTTTGACAAGCTTGATGCCGTGCTGGCCCATGCCGTCATGAGCGTGGGT
GCGGTCAAGGGCGTAGAGGTGGGCGAGGGCTTTGCCGCAGCAGCCCTGCGCGGCTCGCAAAACAACGACCCCCTGCTTCC
GGCGGATGCGCCGGAGCCGGGCAGGGCGCGCTTTGCCTCCAACCATGCAGGCGGCATCCTGGGCGGCATATCCAGCGGAC
AGGATATTGTGCTGCGCGTCGCCGTCAAACCCATAGCCTCCATAGCCGTTACGCAAAAAACCGTGGACAGGCAGGGCCAG
CCCGTGGACATACTCATTGGCGGGCGTCACGACCTGTCCGCCATTCCGCGCATCGTGCCCGTTCTTGAGGCAATGACTGC
CCTGGCCCTGGCAGACGCTCTGCTTTTGCAGCAGCGCATGGGCCTCGGGCTTTAA

Upstream 100 bases:

>100_bases
TGCGCGCCTTGCCAGCCGCGCCGCCCTTTCCTATACTGGCAGGATTGCAGCCGCCGTATGGCGGCCCGAATCCCATTTTC
TGTCCAGCGCGAGGTACACC

Downstream 100 bases:

>100_bases
GGACATAGCATCGCCATGAAGGACATGCCCCTGCTGCAAGACCCGGATGCCGTGGAAATTTCCGGCACTGTGGAGCGCGT
TATCTTTCATAATGAAGAAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MAGNTFGRALRLTTFGESHGPGLGGIIDGCPAGLELTEAHIQAELDRRKPGQGPTATKRKEADTVRLLSGVFEGCTTGTP
IAFFIANEDQRSRDYGNLAEAFRPGHADWAYFQKYNGLRDHRGGGRSSGRETAARVAGGVIAKKILARRGVTILGGCVEL
GGIAAPLWGLDMDGAAARPYCAAAPSVVSQWDALVAEARKAGETLGGIVRIEAHNVPAGLGEPVFDKLDAVLAHAVMSVG
AVKGVEVGEGFAAAALRGSQNNDPLLPADAPEPGRARFASNHAGGILGGISSGQDIVLRVAVKPIASIAVTQKTVDRQGQ
PVDILIGGRHDLSAIPRIVPVLEAMTALALADALLLQQRMGLGL

Sequences:

>Translated_364_residues
MAGNTFGRALRLTTFGESHGPGLGGIIDGCPAGLELTEAHIQAELDRRKPGQGPTATKRKEADTVRLLSGVFEGCTTGTP
IAFFIANEDQRSRDYGNLAEAFRPGHADWAYFQKYNGLRDHRGGGRSSGRETAARVAGGVIAKKILARRGVTILGGCVEL
GGIAAPLWGLDMDGAAARPYCAAAPSVVSQWDALVAEARKAGETLGGIVRIEAHNVPAGLGEPVFDKLDAVLAHAVMSVG
AVKGVEVGEGFAAAALRGSQNNDPLLPADAPEPGRARFASNHAGGILGGISSGQDIVLRVAVKPIASIAVTQKTVDRQGQ
PVDILIGGRHDLSAIPRIVPVLEAMTALALADALLLQQRMGLGL
>Mature_363_residues
AGNTFGRALRLTTFGESHGPGLGGIIDGCPAGLELTEAHIQAELDRRKPGQGPTATKRKEADTVRLLSGVFEGCTTGTPI
AFFIANEDQRSRDYGNLAEAFRPGHADWAYFQKYNGLRDHRGGGRSSGRETAARVAGGVIAKKILARRGVTILGGCVELG
GIAAPLWGLDMDGAAARPYCAAAPSVVSQWDALVAEARKAGETLGGIVRIEAHNVPAGLGEPVFDKLDAVLAHAVMSVGA
VKGVEVGEGFAAAALRGSQNNDPLLPADAPEPGRARFASNHAGGILGGISSGQDIVLRVAVKPIASIAVTQKTVDRQGQP
VDILIGGRHDLSAIPRIVPVLEAMTALALADALLLQQRMGLGL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=53.2033426183844, Blast_Score=335, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=42.9347826086957, Blast_Score=285, Evalue=7e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_DESDA (B8J4Q3)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480861.1
- ProteinModelPortal:   B8J4Q3
- GeneID:   7286006
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_2288
- HOGENOM:   HBG292336
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 37686; Mature: 37555

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNTFGRALRLTTFGESHGPGLGGIIDGCPAGLELTEAHIQAELDRRKPGQGPTATKRK
CCCCCCCCEEEEEECCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHH
EADTVRLLSGVFEGCTTGTPIAFFIANEDQRSRDYGNLAEAFRPGHADWAYFQKYNGLRD
HHHHHHHHHHHHHCCCCCCCEEEEEECCCHHCCHHHHHHHHHCCCCCCHHHHHHHCCCHH
HRGGGRSSGRETAARVAGGVIAKKILARRGVTILGGCVELGGIAAPLWGLDMDGAAARPY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCC
CAAAPSVVSQWDALVAEARKAGETLGGIVRIEAHNVPAGLGEPVFDKLDAVLAHAVMSVG
HHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
AVKGVEVGEGFAAAALRGSQNNDPLLPADAPEPGRARFASNHAGGILGGISSGQDIVLRV
HHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCCCCEEEEEE
AVKPIASIAVTQKTVDRQGQPVDILIGGRHDLSAIPRIVPVLEAMTALALADALLLQQRM
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGL
CCCC
>Mature Secondary Structure 
AGNTFGRALRLTTFGESHGPGLGGIIDGCPAGLELTEAHIQAELDRRKPGQGPTATKRK
CCCCCCCEEEEEECCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHH
EADTVRLLSGVFEGCTTGTPIAFFIANEDQRSRDYGNLAEAFRPGHADWAYFQKYNGLRD
HHHHHHHHHHHHHCCCCCCCEEEEEECCCHHCCHHHHHHHHHCCCCCCHHHHHHHCCCHH
HRGGGRSSGRETAARVAGGVIAKKILARRGVTILGGCVELGGIAAPLWGLDMDGAAARPY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCC
CAAAPSVVSQWDALVAEARKAGETLGGIVRIEAHNVPAGLGEPVFDKLDAVLAHAVMSVG
HHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
AVKGVEVGEGFAAAALRGSQNNDPLLPADAPEPGRARFASNHAGGILGGISSGQDIVLRV
HHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCCCCEEEEEE
AVKPIASIAVTQKTVDRQGQPVDILIGGRHDLSAIPRIVPVLEAMTALALADALLLQQRM
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA