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The map label for this gene is atpD

Identifier: 220905450

GI number: 220905450

Start: 2638878

End: 2640299

Strand: Direct

Name: atpD

Synonym: Ddes_2188

Alternate gene names: 220905450

Gene position: 2638878-2640299 (Clockwise)

Preceding gene: 220905449

Following gene: 220905451

Centisome position: 91.84

GC content: 60.97

Gene sequence:

>1422_bases
ATGAGCAAAAACATCGGTAAAATCGTCCAGGTTATCGGCGCTGTCGTGGACGTTGAGTTCAGCGACGGCAACCTGCCGAA
TATCTTCACCGCCCTGGAGATCAAAAACCCGAACAACACCGACGCCCCGGAACTGATCTGTGAAGTGGCACAGCACCTGG
GCGACAATGTTGTCCGCACCATCGCAATGGACGCCACCGAAGGTCTGGTGCGCGGCATGGACGCGGTCGATACCGGCCAG
CCCATCATGGTGCCCGTGGGCAAGCCCTCCGTGGGCCGTATTCTCAACGTTATCGGCCGCCCCGTGGACGAAATGGGACC
CATTAACGCTGAAAAATACTATCCCATTCACCGCCCGGCTCCGGCCTTTACCGACCAGAACACCAAGGTCGAACTGCTGG
AAACCGGCATCAAGGTTGTGGACCTGCTTGTGCCCTTTCCCAAGGGCGGCAAGATGGGCCTCTTCGGCGGCGCCGGCGTG
GGCAAGACCGTTATCCTGATGGAGATGATCAACAACATCGCCAAGCAGCACGGCGGTTCTTCGGTCTTCGCGGGCGTGGG
CGAACGCACCCGTGAAGGGAACGACCTCTATCACGAACTCAAGGATGCGGGCGTTCTGGAACGCGCCACCCTTGTGTACG
GGCAGATGAACGAGCCTCCGGGAGCGCGTGCGCGCGTGGCCCTTACCGCTCTGGCCTGCGCGGAATACTTCCGCGATGAA
GAACACCAGGACGTGCTCCTCTTCATCGACAACATCTTCCGCTTTACCCAGGCCGGTTCCGAAGTGTCCGCCCTTCTGGG
CCGCATGCCTTCGGCCGTGGGCTACCAGCCCACCCTTGGCACGGACCTTGGTTCGCTGCAGGAACGCATCACGTCCACCA
ATACCGGTTCCATCACGTCGGTGCAGGCCGTTTACGTACCTGCTGACGACCTGACTGACCCGGCCCCGGCCACCACGTTC
TCGCACCTGGACGGCACGCTCGTGCTTTCGCGCCAGATCGCGGAACTGGGCATCTACCCCGCCGTGGACCCGCTGGACTC
CACCTCGCGCATTCTTGACCCCAACGTGGTGGGTGAAGAACACTACGCGGTGGCCCGGCGTGTGCAGATGGTGCTGCAGA
AGTACAAAGAACTGCAGGACATCATCGCCATTCTCGGCATGGACGAACTGTCGGACGAAGACAAGCTCACCGTGGCGCGC
GCGCGCCGCATCCAGCGCTTCCTGTCCCAGCCCTTCCACGTGGCCGAAACCTTTACCGGCACTCCCGGCCAGTACGTGAA
CCTCGAAGACACCATCAAGGGCTTCAAGGGCATTCTGGACGGCGCCTATGACCACATGGCTGAAGGCGACTTCTACATGC
TGGGCGGTATTGAACAGGCCGTGGCCAAGTATGAGCAGCGCAAGCTGCAGGAAGAAAACTAA

Upstream 100 bases:

>100_bases
TGACCCTGCTCTATAACAAAACGCGGCAGGCTTCCATCACCAGCGAACTCATCGACATCGTCGGCGGCGCTGAAGCGCTG
AAGGGTTAAGGAGCCAACTA

Downstream 100 bases:

>100_bases
GAGCGTTGACGCCTGTCATGCGGCCGGGCACGCAGCCCGGCCGCATGACAGCCATAGCTGGCATACAGGAGCGAAGGAGT
ACCTATGGGCACACTGCAAC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MSKNIGKIVQVIGAVVDVEFSDGNLPNIFTALEIKNPNNTDAPELICEVAQHLGDNVVRTIAMDATEGLVRGMDAVDTGQ
PIMVPVGKPSVGRILNVIGRPVDEMGPINAEKYYPIHRPAPAFTDQNTKVELLETGIKVVDLLVPFPKGGKMGLFGGAGV
GKTVILMEMINNIAKQHGGSSVFAGVGERTREGNDLYHELKDAGVLERATLVYGQMNEPPGARARVALTALACAEYFRDE
EHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLGTDLGSLQERITSTNTGSITSVQAVYVPADDLTDPAPATTF
SHLDGTLVLSRQIAELGIYPAVDPLDSTSRILDPNVVGEEHYAVARRVQMVLQKYKELQDIIAILGMDELSDEDKLTVAR
ARRIQRFLSQPFHVAETFTGTPGQYVNLEDTIKGFKGILDGAYDHMAEGDFYMLGGIEQAVAKYEQRKLQEEN

Sequences:

>Translated_473_residues
MSKNIGKIVQVIGAVVDVEFSDGNLPNIFTALEIKNPNNTDAPELICEVAQHLGDNVVRTIAMDATEGLVRGMDAVDTGQ
PIMVPVGKPSVGRILNVIGRPVDEMGPINAEKYYPIHRPAPAFTDQNTKVELLETGIKVVDLLVPFPKGGKMGLFGGAGV
GKTVILMEMINNIAKQHGGSSVFAGVGERTREGNDLYHELKDAGVLERATLVYGQMNEPPGARARVALTALACAEYFRDE
EHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLGTDLGSLQERITSTNTGSITSVQAVYVPADDLTDPAPATTF
SHLDGTLVLSRQIAELGIYPAVDPLDSTSRILDPNVVGEEHYAVARRVQMVLQKYKELQDIIAILGMDELSDEDKLTVAR
ARRIQRFLSQPFHVAETFTGTPGQYVNLEDTIKGFKGILDGAYDHMAEGDFYMLGGIEQAVAKYEQRKLQEEN
>Mature_472_residues
SKNIGKIVQVIGAVVDVEFSDGNLPNIFTALEIKNPNNTDAPELICEVAQHLGDNVVRTIAMDATEGLVRGMDAVDTGQP
IMVPVGKPSVGRILNVIGRPVDEMGPINAEKYYPIHRPAPAFTDQNTKVELLETGIKVVDLLVPFPKGGKMGLFGGAGVG
KTVILMEMINNIAKQHGGSSVFAGVGERTREGNDLYHELKDAGVLERATLVYGQMNEPPGARARVALTALACAEYFRDEE
HQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLGTDLGSLQERITSTNTGSITSVQAVYVPADDLTDPAPATTFS
HLDGTLVLSRQIAELGIYPAVDPLDSTSRILDPNVVGEEHYAVARRVQMVLQKYKELQDIIAILGMDELSDEDKLTVARA
RRIQRFLSQPFHVAETFTGTPGQYVNLEDTIKGFKGILDGAYDHMAEGDFYMLGGIEQAVAKYEQRKLQEEN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=474, Percent_Identity=70.253164556962, Blast_Score=670, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=348, Percent_Identity=28.448275862069, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19913428, Length=361, Percent_Identity=24.9307479224377, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI19913426, Length=365, Percent_Identity=24.9315068493151, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI50345984, Length=344, Percent_Identity=25.5813953488372, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI4757810, Length=344, Percent_Identity=25.5813953488372, Blast_Score=99, Evalue=9e-21,
Organism=Escherichia coli, GI1790170, Length=461, Percent_Identity=68.5466377440347, Blast_Score=645, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=403, Percent_Identity=29.2803970223325, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790172, Length=438, Percent_Identity=24.2009132420091, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25144756, Length=474, Percent_Identity=69.4092827004219, Blast_Score=664, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570191, Length=361, Percent_Identity=25.7617728531856, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17510931, Length=350, Percent_Identity=25.4285714285714, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17565854, Length=322, Percent_Identity=28.2608695652174, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=380, Percent_Identity=25.5263157894737, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=380, Percent_Identity=25.5263157894737, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71988074, Length=361, Percent_Identity=24.9307479224377, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=461, Percent_Identity=70.2819956616052, Blast_Score=660, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=357, Percent_Identity=27.4509803921569, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319370, Length=347, Percent_Identity=26.5129682997118, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320016, Length=233, Percent_Identity=30.0429184549356, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24638766, Length=467, Percent_Identity=71.5203426124197, Blast_Score=670, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=469, Percent_Identity=66.7377398720682, Blast_Score=619, Evalue=1e-177,
Organism=Drosophila melanogaster, GI20129479, Length=335, Percent_Identity=29.2537313432836, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281361666, Length=405, Percent_Identity=26.1728395061728, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24646341, Length=405, Percent_Identity=26.1728395061728, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136796, Length=405, Percent_Identity=26.1728395061728, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24583988, Length=326, Percent_Identity=28.5276073619632, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24583986, Length=326, Percent_Identity=28.5276073619632, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24583984, Length=326, Percent_Identity=28.5276073619632, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24583992, Length=348, Percent_Identity=27.8735632183908, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24638768, Length=95, Percent_Identity=64.2105263157895, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24658560, Length=380, Percent_Identity=25, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_DESDA (B8J439)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480762.1
- ProteinModelPortal:   B8J439
- GeneID:   7285904
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_2188
- HOGENOM:   HBG565875
- ProtClustDB:   PRK09280
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 51398; Mature: 51267

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNIGKIVQVIGAVVDVEFSDGNLPNIFTALEIKNPNNTDAPELICEVAQHLGDNVVRT
CCCCHHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHH
IAMDATEGLVRGMDAVDTGQPIMVPVGKPSVGRILNVIGRPVDEMGPINAEKYYPIHRPA
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCC
PAFTDQNTKVELLETGIKVVDLLVPFPKGGKMGLFGGAGVGKTVILMEMINNIAKQHGGS
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCC
SVFAGVGERTREGNDLYHELKDAGVLERATLVYGQMNEPPGARARVALTALACAEYFRDE
CEECCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
EHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLGTDLGSLQERITSTNTGSITS
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEE
VQAVYVPADDLTDPAPATTFSHLDGTLVLSRQIAELGIYPAVDPLDSTSRILDPNVVGEE
EEEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCHH
HYAVARRVQMVLQKYKELQDIIAILGMDELSDEDKLTVARARRIQRFLSQPFHVAETFTG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCC
TPGQYVNLEDTIKGFKGILDGAYDHMAEGDFYMLGGIEQAVAKYEQRKLQEEN
CCCCEECHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKNIGKIVQVIGAVVDVEFSDGNLPNIFTALEIKNPNNTDAPELICEVAQHLGDNVVRT
CCCHHHHHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHH
IAMDATEGLVRGMDAVDTGQPIMVPVGKPSVGRILNVIGRPVDEMGPINAEKYYPIHRPA
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCC
PAFTDQNTKVELLETGIKVVDLLVPFPKGGKMGLFGGAGVGKTVILMEMINNIAKQHGGS
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCC
SVFAGVGERTREGNDLYHELKDAGVLERATLVYGQMNEPPGARARVALTALACAEYFRDE
CEECCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
EHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLGTDLGSLQERITSTNTGSITS
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEE
VQAVYVPADDLTDPAPATTFSHLDGTLVLSRQIAELGIYPAVDPLDSTSRILDPNVVGEE
EEEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCHH
HYAVARRVQMVLQKYKELQDIIAILGMDELSDEDKLTVARARRIQRFLSQPFHVAETFTG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCC
TPGQYVNLEDTIKGFKGILDGAYDHMAEGDFYMLGGIEQAVAKYEQRKLQEEN
CCCCEECHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA