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The map label for this gene is aroK2 [H]

Identifier: 220905443

GI number: 220905443

Start: 2632779

End: 2633387

Strand: Direct

Name: aroK2 [H]

Synonym: Ddes_2181

Alternate gene names: 220905443

Gene position: 2632779-2633387 (Clockwise)

Preceding gene: 220905442

Following gene: 220905444

Centisome position: 91.62

GC content: 66.83

Gene sequence:

>609_bases
ATGCCGCTCATCTTTCTCGTAGGCCCCAGAGCCTGCGGCAAAACCACCGTAGGGCGCACCCTGGCCCGGCGGCTTGGCCT
GCCCTTTGTGGATACGGACCATTTTCTCCATCACCAGACGGGGCGCACCGTGGCCCAGATAGTCGCAGCCGAGGGCTGGC
CCGGCTTCCGCCGCCTCGAAAGCGAGGCCCTGCGCGCCACAGCCGGGCTGCATCAGACTTCCGGGGCCGTTATCGCCACC
GGCGGCGGTATGGTCCTGGACGCACAAAACCGCGCCTTCATGCGTGAGCAGGGGTGCGTGTTCTATCTGTCGGCTTCTGC
GGAAGCACTGGTCGCCCGTCTGTCGGGCAACCCTCTTGCTGCTCAAAGGCCCTCGCTCACCGGAACCGACATCAGGGAAG
AAGTTGCCCAGGTCCTGCAGGAGCGGCTCCCCCTCTATGAACAGACCGCCCACCACCGGCTTGATGCGGCGCTTTCGCCC
GGGCGCATCTGCGCACAGGCCCTGACCCTGCTGTGCGGGCCGGACGATCCAGCCGCACCGACTGTGCCGGAAAGCGGCAA
GGACATCCCACAAGCCCCCGCTCCGGACGGAGGTGCCACGAGTGCATAG

Upstream 100 bases:

>100_bases
CTGGCCCGGACCGCGACCAGTGACCGTCCGGCATACCGACCCGCGCGCGGTCCGATATTTTCTCACTGCGCCACGGGGCG
CACAGCCACCAGGAACATTC

Downstream 100 bases:

>100_bases
CCTCTTTCCGGATGCCTCCGCCCCCGGGCAGCCGCTGGTTACGGTGCTGTTGCCCGCCTACAACGCCGCCCACACCCTTG
AAGCCGCCCTGCACAGCCTT

Product: Shikimate kinase

Products: NA

Alternate protein names: SK 2 [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPLIFLVGPRACGKTTVGRTLARRLGLPFVDTDHFLHHQTGRTVAQIVAAEGWPGFRRLESEALRATAGLHQTSGAVIAT
GGGMVLDAQNRAFMREQGCVFYLSASAEALVARLSGNPLAAQRPSLTGTDIREEVAQVLQERLPLYEQTAHHRLDAALSP
GRICAQALTLLCGPDDPAAPTVPESGKDIPQAPAPDGGATSA

Sequences:

>Translated_202_residues
MPLIFLVGPRACGKTTVGRTLARRLGLPFVDTDHFLHHQTGRTVAQIVAAEGWPGFRRLESEALRATAGLHQTSGAVIAT
GGGMVLDAQNRAFMREQGCVFYLSASAEALVARLSGNPLAAQRPSLTGTDIREEVAQVLQERLPLYEQTAHHRLDAALSP
GRICAQALTLLCGPDDPAAPTVPESGKDIPQAPAPDGGATSA
>Mature_201_residues
PLIFLVGPRACGKTTVGRTLARRLGLPFVDTDHFLHHQTGRTVAQIVAAEGWPGFRRLESEALRATAGLHQTSGAVIATG
GGMVLDAQNRAFMREQGCVFYLSASAEALVARLSGNPLAAQRPSLTGTDIREEVAQVLQERLPLYEQTAHHRLDAALSPG
RICAQALTLLCGPDDPAAPTVPESGKDIPQAPAPDGGATSA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fifth step. [C]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786587, Length=163, Percent_Identity=47.239263803681, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=34.3373493975904, Blast_Score=90, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=153, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 21264; Mature: 21133

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLIFLVGPRACGKTTVGRTLARRLGLPFVDTDHFLHHQTGRTVAQIVAAEGWPGFRRLE
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHH
SEALRATAGLHQTSGAVIATGGGMVLDAQNRAFMREQGCVFYLSASAEALVARLSGNPLA
HHHHHHHHCCCCCCCEEEEECCCEEEECCCCHHHHHCCEEEEEECCHHHHHHHHCCCCCC
AQRPSLTGTDIREEVAQVLQERLPLYEQTAHHRLDAALSPGRICAQALTLLCGPDDPAAP
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
TVPESGKDIPQAPAPDGGATSA
CCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLIFLVGPRACGKTTVGRTLARRLGLPFVDTDHFLHHQTGRTVAQIVAAEGWPGFRRLE
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHH
SEALRATAGLHQTSGAVIATGGGMVLDAQNRAFMREQGCVFYLSASAEALVARLSGNPLA
HHHHHHHHCCCCCCCEEEEECCCEEEECCCCHHHHHCCEEEEEECCHHHHHHHHCCCCCC
AQRPSLTGTDIREEVAQVLQERLPLYEQTAHHRLDAALSPGRICAQALTLLCGPDDPAAP
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
TVPESGKDIPQAPAPDGGATSA
CCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA