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The map label for this gene is hybB [C]

Identifier: 220905302

GI number: 220905302

Start: 2452928

End: 2454142

Strand: Direct

Name: hybB [C]

Synonym: Ddes_2040

Alternate gene names: 220905302

Gene position: 2452928-2454142 (Clockwise)

Preceding gene: 220905301

Following gene: 220905303

Centisome position: 85.37

GC content: 56.79

Gene sequence:

>1215_bases
ATGTCACAGCACAGCATCGTCATTCCCAGCAAGGGCAAGCTGTTTAACCTGGACGAGTTTCTCAAACCTACTCCGGGCAA
TATCATCACCGCCATCATCCTGACGGTGGGCCTGATAATTACCGTTATCCGCTTTACCATGGGCATCGGCTCGGTCACCA
ACCTGAGCAACACCCAGCCCTGGGGCCTTTGGATCGGCTTTGACCTGCTTTGCGGCGTGGCGCTGGCGGCAGGTGGCTAC
TTTACCACCGTGGCCTGCTACGTCATGGGCATGAAGCAGTTTCACTCCGCCGTGCGCCCGGCCATTACCACGGCCTTTCT
CGGCTACGGTTTTGTGGTCGTGGCCCTTCTGTATGACCTGGGCCATCCACTGCGGCTGCCCTTCATGTTCTTCTTCCCGG
GAACCACCTCGGTACTCTTTGAAGTGGGCCTGTGCGTGGCCACCTACGTTACGGTGCTCTTCATCGAGTTTTCCGTGGCG
CCTATGGAATGGCTGGCACAAAAGTTCCCCTGCCTTATCAAATGGCGCAGGCTCGTGGTGCACAGCACCATCGTGCTCAC
CATTTTTGGCGTTACCCTGTCCACCCTGCATCAGTCGTCACTGGGCGCGCTCTACCTGATTGCGCCTGAAAAGCTGCACC
CCCTGTGGTATTCGCCCTTCATGCCCATGTTTTTCTTCGTCAGCTCGATGGCTGCCGGAGCCTCCATGGTCATCTTTGAA
GGCATATTTGCCCACAAGGGTCTGCACCATTATATGGACGAAACCCACCTGCGTGAATCTGACGGCGTGGTCCTCAGCTT
TTCCCGCGCTGCTTCTTTCATCCTGTTCGCCTACTTCATGCTCAAGCTTATCGACATGCTTGTGCAGGCCAACCTGCCCT
ACGTTTTCTCGGGCTACGGGGCCTGGTGGCTGGTTGAAATGCTGGGCTTCGTGCTGTTGCCCGCCCTGCTCTATGCCAAG
GGCGCACGCGACCGCAACCTGACCCTGTGCCGTATTGCGTCGGCCAATACCGTGCTGGGCATCGTTCTGAACCGCTTCAA
CGTGTCCATGATCGCCTTCAACTACAACCTGCCCCCGGCGGAACGCTACTTCCCCAGCATTTGGGAAATATGCATTTCCA
TCTTTGTGGTAACGATGATCGTGACCGTGTACCGCTTTATCATCTACCACATGCCGGTGCTGTACGAACACCCCGACTTC
AGGGATGAGCACTAG

Upstream 100 bases:

>100_bases
AACCCAGGGGCCGGGCGCTGCCGATACGGCCCGCCGCGCCATGACAGAGGCCCTCAAGGCCCGCGAAACGGCGTGCACGG
GGCACGGGGAGGATAAGTAA

Downstream 100 bases:

>100_bases
CCAACAGGGAGAGGAGAATACTATGGAATTCCATACTTTTTACGATTACTTCCTCTATACGAAGAGCTGGGCTTACGCCA
TGATGTTTGTGGTTCTGCCC

Product: polysulfide reductase NrfD

Products: NA

Alternate protein names: HMC operon ORF 3 [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSQHSIVIPSKGKLFNLDEFLKPTPGNIITAIILTVGLIITVIRFTMGIGSVTNLSNTQPWGLWIGFDLLCGVALAAGGY
FTTVACYVMGMKQFHSAVRPAITTAFLGYGFVVVALLYDLGHPLRLPFMFFFPGTTSVLFEVGLCVATYVTVLFIEFSVA
PMEWLAQKFPCLIKWRRLVVHSTIVLTIFGVTLSTLHQSSLGALYLIAPEKLHPLWYSPFMPMFFFVSSMAAGASMVIFE
GIFAHKGLHHYMDETHLRESDGVVLSFSRAASFILFAYFMLKLIDMLVQANLPYVFSGYGAWWLVEMLGFVLLPALLYAK
GARDRNLTLCRIASANTVLGIVLNRFNVSMIAFNYNLPPAERYFPSIWEICISIFVVTMIVTVYRFIIYHMPVLYEHPDF
RDEH

Sequences:

>Translated_404_residues
MSQHSIVIPSKGKLFNLDEFLKPTPGNIITAIILTVGLIITVIRFTMGIGSVTNLSNTQPWGLWIGFDLLCGVALAAGGY
FTTVACYVMGMKQFHSAVRPAITTAFLGYGFVVVALLYDLGHPLRLPFMFFFPGTTSVLFEVGLCVATYVTVLFIEFSVA
PMEWLAQKFPCLIKWRRLVVHSTIVLTIFGVTLSTLHQSSLGALYLIAPEKLHPLWYSPFMPMFFFVSSMAAGASMVIFE
GIFAHKGLHHYMDETHLRESDGVVLSFSRAASFILFAYFMLKLIDMLVQANLPYVFSGYGAWWLVEMLGFVLLPALLYAK
GARDRNLTLCRIASANTVLGIVLNRFNVSMIAFNYNLPPAERYFPSIWEICISIFVVTMIVTVYRFIIYHMPVLYEHPDF
RDEH
>Mature_403_residues
SQHSIVIPSKGKLFNLDEFLKPTPGNIITAIILTVGLIITVIRFTMGIGSVTNLSNTQPWGLWIGFDLLCGVALAAGGYF
TTVACYVMGMKQFHSAVRPAITTAFLGYGFVVVALLYDLGHPLRLPFMFFFPGTTSVLFEVGLCVATYVTVLFIEFSVAP
MEWLAQKFPCLIKWRRLVVHSTIVLTIFGVTLSTLHQSSLGALYLIAPEKLHPLWYSPFMPMFFFVSSMAAGASMVIFEG
IFAHKGLHHYMDETHLRESDGVVLSFSRAASFILFAYFMLKLIDMLVQANLPYVFSGYGAWWLVEMLGFVLLPALLYAKG
ARDRNLTLCRIASANTVLGIVLNRFNVSMIAFNYNLPPAERYFPSIWEICISIFVVTMIVTVYRFIIYHMPVLYEHPDFR
DEH

Specific function: HMWC (high-molecular-weight cytochrome c), ORF2, ORF3, ORF4, ORF5 and ORF6 in the HMC operon form a transmembrane protein complex that allows electron flow from the periplasmic hydrogenase to the cytoplasmic enzymes that catalyze reduction of sulfates [H]

COG id: COG5557

COG function: function code C; Polysulphide reductase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nrfD family [H]

Homologues:

Organism=Escherichia coli, GI2367183, Length=397, Percent_Identity=31.2342569269521, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005614 [H]

Pfam domain/function: PF03916 NrfD [H]

EC number: NA

Molecular weight: Translated: 45422; Mature: 45290

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCC
>Mature Secondary Structure 
SQHSIVIPSKGKLFNLDEFLKPTPGNIITAIILTVGLIITVIRFTMGIGSVTNLSNTQP
CCCCEEECCCCCEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
WGLWIGFDLLCGVALAAGGYFTTVACYVMGMKQFHSAVRPAITTAFLGYGFVVVALLYDL
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GHPLRLPFMFFFPGTTSVLFEVGLCVATYVTVLFIEFSVAPMEWLAQKFPCLIKWRRLVV
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHH
HSTIVLTIFGVTLSTLHQSSLGALYLIAPEKLHPLWYSPFMPMFFFVSSMAAGASMVIFE
HHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHH
GIFAHKGLHHYMDETHLRESDGVVLSFSRAASFILFAYFMLKLIDMLVQANLPYVFSGYG
HHHHHCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCH
AWWLVEMLGFVLLPALLYAKGARDRNLTLCRIASANTVLGIVLNRFNVSMIAFNYNLPPA
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCEEEEEEECCCCCH
ERYFPSIWEICISIFVVTMIVTVYRFIIYHMPVLYEHPDFRDEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8335628 [H]