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The map label for this gene is yggV [C]

Identifier: 220905154

GI number: 220905154

Start: 2281427

End: 2282056

Strand: Direct

Name: yggV [C]

Synonym: Ddes_1892

Alternate gene names: 220905154

Gene position: 2281427-2282056 (Clockwise)

Preceding gene: 220905153

Following gene: 220905155

Centisome position: 79.4

GC content: 58.25

Gene sequence:

>630_bases
ATGAGTACACAGCCCATACGTATCGTGCTGGCGACCCACAATGCGGGGAAAGTACGCGAACTGGCCGACCCGCTGGCCCG
ATTCGGTGTGGAGGTACTGAGTCTTGAGGCCTTTCCTCACATTGGTGAAATTGAAGAAACCGGTGTAACTTTTGAAGAAA
ACGCCTGCATCAAGGCGCGTGAGGTAGCCCGCCTGACCGGCCTCGTGAGCATTGCCGACGATTCCGGCCTGGAGGTGGAC
GCCCTGGACGGCAAGCCCGGCGTCTATTCGGCCCGCTATTCCGACGACTGGCAAAGCCTGCCCGACGAAAGCCGGGATGA
CCGCAATATCCGCAAACTGCTGCACGAACTGGCGGATGTTCCGGAAAATAAAAGAGGTTGCCGCTTTGTGAGCTGCATGG
CCTGCGTGCGGCCCGACGGCGCGGAAATGGTCGTTCGCGGCAACTGGGAAGGCACACTGCTTCATGCCCCGCGTGGCCAG
AACGGCTTTGGTTATGACCCTGTCTTTTTTGATAAAGACATACAAAAAACCGCAGCAGAACTGACCAGGGACGAAAAAAA
TGCCCGCAGCCACAGGGGCAACGCCCTGCGCGCGCTTCTGGCAAAGTGGCAGAGCTTTATGGGCGCGTAA

Upstream 100 bases:

>100_bases
CGCACTGGTTATCAGCGGCATCATCATCGCCACGCTGGTTCTGCCCCAGCACAGGGCAAAAGCCTGAAACCACCTGCGGC
ACAGCCGCCAAGGAGCATAT

Downstream 100 bases:

>100_bases
CCGGCCATGCCCACAGCGGCATACGGCAGCGGTTTTTTGTTTTTCCACCCTTTTCTGTTAAAGCATACGCACCTTGAAAT
GCCTGCCCGACGGCGAAACA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSTQPIRIVLATHNAGKVRELADPLARFGVEVLSLEAFPHIGEIEETGVTFEENACIKAREVARLTGLVSIADDSGLEVD
ALDGKPGVYSARYSDDWQSLPDESRDDRNIRKLLHELADVPENKRGCRFVSCMACVRPDGAEMVVRGNWEGTLLHAPRGQ
NGFGYDPVFFDKDIQKTAAELTRDEKNARSHRGNALRALLAKWQSFMGA

Sequences:

>Translated_209_residues
MSTQPIRIVLATHNAGKVRELADPLARFGVEVLSLEAFPHIGEIEETGVTFEENACIKAREVARLTGLVSIADDSGLEVD
ALDGKPGVYSARYSDDWQSLPDESRDDRNIRKLLHELADVPENKRGCRFVSCMACVRPDGAEMVVRGNWEGTLLHAPRGQ
NGFGYDPVFFDKDIQKTAAELTRDEKNARSHRGNALRALLAKWQSFMGA
>Mature_208_residues
STQPIRIVLATHNAGKVRELADPLARFGVEVLSLEAFPHIGEIEETGVTFEENACIKAREVARLTGLVSIADDSGLEVDA
LDGKPGVYSARYSDDWQSLPDESRDDRNIRKLLHELADVPENKRGCRFVSCMACVRPDGAEMVVRGNWEGTLLHAPRGQN
GFGYDPVFFDKDIQKTAAELTRDEKNARSHRGNALRALLAKWQSFMGA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=48.469387755102, Blast_Score=179, Evalue=1e-46,
Organism=Drosophila melanogaster, GI19920712, Length=193, Percent_Identity=31.0880829015544, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 23138; Mature: 23007

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQPIRIVLATHNAGKVRELADPLARFGVEVLSLEAFPHIGEIEETGVTFEENACIKAR
CCCCCEEEEEEECCCCHHHHHHHHHHHHCHHHEEHHCCCCCCCHHHCCCEECCCCCHHHH
EVARLTGLVSIADDSGLEVDALDGKPGVYSARYSDDWQSLPDESRDDRNIRKLLHELADV
HHHHHHHHEEECCCCCCEEEECCCCCCEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHCC
PENKRGCRFVSCMACVRPDGAEMVVRGNWEGTLLHAPRGQNGFGYDPVFFDKDIQKTAAE
CCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEECHHHHHHHHH
LTRDEKNARSHRGNALRALLAKWQSFMGA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STQPIRIVLATHNAGKVRELADPLARFGVEVLSLEAFPHIGEIEETGVTFEENACIKAR
CCCCEEEEEEECCCCHHHHHHHHHHHHCHHHEEHHCCCCCCCHHHCCCEECCCCCHHHH
EVARLTGLVSIADDSGLEVDALDGKPGVYSARYSDDWQSLPDESRDDRNIRKLLHELADV
HHHHHHHHEEECCCCCCEEEECCCCCCEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHCC
PENKRGCRFVSCMACVRPDGAEMVVRGNWEGTLLHAPRGQNGFGYDPVFFDKDIQKTAAE
CCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEECHHHHHHHHH
LTRDEKNARSHRGNALRALLAKWQSFMGA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA