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The map label for this gene is mtaD [H]

Identifier: 220905136

GI number: 220905136

Start: 2257861

End: 2259159

Strand: Direct

Name: mtaD [H]

Synonym: Ddes_1874

Alternate gene names: 220905136

Gene position: 2257861-2259159 (Clockwise)

Preceding gene: 220905135

Following gene: 220905137

Centisome position: 78.58

GC content: 65.82

Gene sequence:

>1299_bases
ATGAACCCCAAGGGGCCTTCAGATTTACCTACAGGTTCACGAGCGGCCTTCGCGCAACCTCAAAACGGAAACGCCGACGG
CCGTGCGGATCAGTTCGCCGGGCCTGCGCTGGCGATCAGGGCCAGAAGCATTGTGACCCTGGCGGGCGAAGGCCCGTCCA
GAGGGGCGCGGCTGTTTGCGCCCCTGAAAAAGATCGACAATGCCGTGCTTATCGTGCGTGGCGGCCTGGTGGAAGAGGTG
CGCCCCTGGTCTGCCGCTGCGGCGCCCGCCGGAGCTGTCGTGCGCGATGTGGGCGCTGTGTGCCTGGCCCCGGCCTGCGT
CAACGCGCACACGCATCTTGAACTCTCGCATCTTGCCGGGCGCACGGTATGGGGCAAAGGTTTCACCGCATGGCTGCAAA
GCCTCGTTCCTTTGCTGCCTGAAGCCCCCGATGCGCAGGCTGTGGAAAATGCCTGCGCTCATCTGGCCGGAACCGGCACC
CTGTACGCGGGTAATATTACCGGCTCGTTGCCGGGCGGCACGCTTCTGGCTGACGCCGCCTGCCGGGAAACGGGCATTGC
CGCAAGCCATTTTTGCGAATGGTTCGGTTTTGGCGCGCCCTTTGCCGACGGTATCCGCCCCTGGCCGCCCCGCTGCCGCC
AGGTTCTGCAGGACGATCCCTTTCTGGCAGCCCGATGCGCCCCCGGCGGGCATGCCCTGTATTCCACCGGGGCTGACATC
TTGACTGCCGCCAGGCAGGACTGCGCCCGCATGGGCCGTATTTTCAGCTTTCATCTGGCGGAATCCCCCGATGAGACGCA
GATGCTGGTCACGGGTGACGGCCCCTTGCGCCATTTCTACGAAAAGGCGGTCCTGCCCGAAGACTGGCAGGCCCCCGGCC
TGCGCCCCCTGGCCTACGCCGTCAAGCTGGGGCTTCTCGGCACGGGTACCCTTGCTGTACACGGTACACAGCTTGACGCC
CAGGAAGTGGAGGTGCTGGCCGCCAGCGGCACGGCCCTGTGCCTGTGCCCGCGCTCCAACCGCAATCTTGACCTTGGCGT
GCCGCCGGTGCGCGACCTGCTTGAAAGCGGCTGCCTGCTCTGCCTCGGTACGGACGGTCTGACCAGCAACCGCGACCTGG
ATGTGCGGCAGGAAGCCGTATGGCTGCGTGACAACCTTGACGTTCCACCCGAAGCCCTGGTGCGCCTCATGACTGTCAAC
GGCGCTGCTGCCCTCAACCTGCTCCCCAGTGGCGCAGGCCGTCTGGAACCCGGCAGTCCGGCGGCATTCTGCGTATTGCC
CGAAGCCCTCGTCTATTAG

Upstream 100 bases:

>100_bases
ACCTGGTGTACAGCATTGACCCCAATGCCCTCTTTATTGTTGAAAATACCTTCTATGTCTCCGGCGGGCAGTTTGCCCGG
CGCGGGCGGTAGGAACACGC

Downstream 100 bases:

>100_bases
AGCACCTTACCTTGAAAATGCTTTGGCGACTGCGTGAACAGCGCCCGCCGCGAAGGCGCAAGCCCAGTGTATTTGCGCGA
CTAGAGCAATAACGCTTCAA

Product: amidohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MNPKGPSDLPTGSRAAFAQPQNGNADGRADQFAGPALAIRARSIVTLAGEGPSRGARLFAPLKKIDNAVLIVRGGLVEEV
RPWSAAAAPAGAVVRDVGAVCLAPACVNAHTHLELSHLAGRTVWGKGFTAWLQSLVPLLPEAPDAQAVENACAHLAGTGT
LYAGNITGSLPGGTLLADAACRETGIAASHFCEWFGFGAPFADGIRPWPPRCRQVLQDDPFLAARCAPGGHALYSTGADI
LTAARQDCARMGRIFSFHLAESPDETQMLVTGDGPLRHFYEKAVLPEDWQAPGLRPLAYAVKLGLLGTGTLAVHGTQLDA
QEVEVLAASGTALCLCPRSNRNLDLGVPPVRDLLESGCLLCLGTDGLTSNRDLDVRQEAVWLRDNLDVPPEALVRLMTVN
GAAALNLLPSGAGRLEPGSPAAFCVLPEALVY

Sequences:

>Translated_432_residues
MNPKGPSDLPTGSRAAFAQPQNGNADGRADQFAGPALAIRARSIVTLAGEGPSRGARLFAPLKKIDNAVLIVRGGLVEEV
RPWSAAAAPAGAVVRDVGAVCLAPACVNAHTHLELSHLAGRTVWGKGFTAWLQSLVPLLPEAPDAQAVENACAHLAGTGT
LYAGNITGSLPGGTLLADAACRETGIAASHFCEWFGFGAPFADGIRPWPPRCRQVLQDDPFLAARCAPGGHALYSTGADI
LTAARQDCARMGRIFSFHLAESPDETQMLVTGDGPLRHFYEKAVLPEDWQAPGLRPLAYAVKLGLLGTGTLAVHGTQLDA
QEVEVLAASGTALCLCPRSNRNLDLGVPPVRDLLESGCLLCLGTDGLTSNRDLDVRQEAVWLRDNLDVPPEALVRLMTVN
GAAALNLLPSGAGRLEPGSPAAFCVLPEALVY
>Mature_432_residues
MNPKGPSDLPTGSRAAFAQPQNGNADGRADQFAGPALAIRARSIVTLAGEGPSRGARLFAPLKKIDNAVLIVRGGLVEEV
RPWSAAAAPAGAVVRDVGAVCLAPACVNAHTHLELSHLAGRTVWGKGFTAWLQSLVPLLPEAPDAQAVENACAHLAGTGT
LYAGNITGSLPGGTLLADAACRETGIAASHFCEWFGFGAPFADGIRPWPPRCRQVLQDDPFLAARCAPGGHALYSTGADI
LTAARQDCARMGRIFSFHLAESPDETQMLVTGDGPLRHFYEKAVLPEDWQAPGLRPLAYAVKLGLLGTGTLAVHGTQLDA
QEVEVLAASGTALCLCPRSNRNLDLGVPPVRDLLESGCLLCLGTDGLTSNRDLDVRQEAVWLRDNLDVPPEALVRLMTVN
GAAALNLLPSGAGRLEPGSPAAFCVLPEALVY

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 45137; Mature: 45137

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKGPSDLPTGSRAAFAQPQNGNADGRADQFAGPALAIRARSIVTLAGEGPSRGARLFA
CCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHCCCEEEEEEEEEEEEECCCCCCCCHHHH
PLKKIDNAVLIVRGGLVEEVRPWSAAAAPAGAVVRDVGAVCLAPACVNAHTHLELSHLAG
HHHHCCCEEEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCC
RTVWGKGFTAWLQSLVPLLPEAPDAQAVENACAHLAGTGTLYAGNITGSLPGGTLLADAA
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEHHHH
CRETGIAASHFCEWFGFGAPFADGIRPWPPRCRQVLQDDPFLAARCAPGGHALYSTGADI
HHHCCCHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHCCCCCEEEECCCCCCCHHHCCHHH
LTAARQDCARMGRIFSFHLAESPDETQMLVTGDGPLRHFYEKAVLPEDWQAPGLRPLAYA
HHHHHHHHHHHHHHEEEEECCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHH
VKLGLLGTGTLAVHGTQLDAQEVEVLAASGTALCLCPRSNRNLDLGVPPVRDLLESGCLL
HHHHCEECCEEEEECCCCCHHHHEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHCCCEE
CLGTDGLTSNRDLDVRQEAVWLRDNLDVPPEALVRLMTVNGAAALNLLPSGAGRLEPGSP
EEECCCCCCCCCCCHHHHEEEEECCCCCCHHHHHEEHEECCCEEEEECCCCCCCCCCCCC
AAFCVLPEALVY
EEEEECCHHHCC
>Mature Secondary Structure
MNPKGPSDLPTGSRAAFAQPQNGNADGRADQFAGPALAIRARSIVTLAGEGPSRGARLFA
CCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHCCCEEEEEEEEEEEEECCCCCCCCHHHH
PLKKIDNAVLIVRGGLVEEVRPWSAAAAPAGAVVRDVGAVCLAPACVNAHTHLELSHLAG
HHHHCCCEEEEEECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHCC
RTVWGKGFTAWLQSLVPLLPEAPDAQAVENACAHLAGTGTLYAGNITGSLPGGTLLADAA
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEHHHH
CRETGIAASHFCEWFGFGAPFADGIRPWPPRCRQVLQDDPFLAARCAPGGHALYSTGADI
HHHCCCHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHCCCCCEEEECCCCCCCHHHCCHHH
LTAARQDCARMGRIFSFHLAESPDETQMLVTGDGPLRHFYEKAVLPEDWQAPGLRPLAYA
HHHHHHHHHHHHHHEEEEECCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHH
VKLGLLGTGTLAVHGTQLDAQEVEVLAASGTALCLCPRSNRNLDLGVPPVRDLLESGCLL
HHHHCEECCEEEEECCCCCHHHHEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHCCCEE
CLGTDGLTSNRDLDVRQEAVWLRDNLDVPPEALVRLMTVNGAAALNLLPSGAGRLEPGSP
EEECCCCCCCCCCCHHHHEEEEECCCCCCHHHHHEEHEECCCEEEEECCCCCCCCCCCCC
AAFCVLPEALVY
EEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA