Click here to switch to the map view.

The map label for this gene is mdtI [H]

Identifier: 220905076

GI number: 220905076

Start: 2187012

End: 2187350

Strand: Direct

Name: mdtI [H]

Synonym: Ddes_1813

Alternate gene names: 220905076

Gene position: 2187012-2187350 (Clockwise)

Preceding gene: 220905075

Following gene: 220905077

Centisome position: 76.11

GC content: 57.82

Gene sequence:

>339_bases
ATGCAGCCCCTTACCTCTTTTTTCAGCCTCTCCCTTTTACTGGTGGTGATGGCGGCGGCACTGGACGTACTGGCAAACCT
GCTGCTGGCAAAATCCGGCGGCTTCAGGCGGCGCTGGCTGGGATTTTTCTCTCTGGTGCTGGTGGGCCTTGCTTTCTATT
GCCTGTCGCTGGCCGTACGCCATATGGATCTGGCTGTGGCGTATGCCATGTGGGGCAGTTTCGGTATTCTGGGCACGTCG
CTGGGTGGCTGGCTGTTTTTCAGCCAGAAGCTGCGCCCCTGCGCTTTTGCGGGCATGGCTCTGCTCATGACGGGCATGGC
TCTTTTGCATATGAGTTAA

Upstream 100 bases:

>100_bases
ACGGCACAGGGCACGGCAAAGAAGACATACACCCGGCTGCCCGCCCCACGTCCAGCCTGAATGCGGGCGGCAATGCCGCT
GGTGAACGGGGGAACGCATA

Downstream 100 bases:

>100_bases
TTACTGCCCTGCAAATAAAAAACATACCCGCCGGACAAGGCAGAGCAGCGGAAAATGCACGCAGCGGCCTCGCCCGGCCA
ACGCACTGCAGACGAAAGAA

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MQPLTSFFSLSLLLVVMAAALDVLANLLLAKSGGFRRRWLGFFSLVLVGLAFYCLSLAVRHMDLAVAYAMWGSFGILGTS
LGGWLFFSQKLRPCAFAGMALLMTGMALLHMS

Sequences:

>Translated_112_residues
MQPLTSFFSLSLLLVVMAAALDVLANLLLAKSGGFRRRWLGFFSLVLVGLAFYCLSLAVRHMDLAVAYAMWGSFGILGTS
LGGWLFFSQKLRPCAFAGMALLMTGMALLHMS
>Mature_112_residues
MQPLTSFFSLSLLLVVMAAALDVLANLLLAKSGGFRRRWLGFFSLVLVGLAFYCLSLAVRHMDLAVAYAMWGSFGILGTS
LGGWLFFSQKLRPCAFAGMALLMTGMALLHMS

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787883, Length=96, Percent_Identity=43.75, Blast_Score=74, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12170; Mature: 12170

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPLTSFFSLSLLLVVMAAALDVLANLLLAKSGGFRRRWLGFFSLVLVGLAFYCLSLAVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HMDLAVAYAMWGSFGILGTSLGGWLFFSQKLRPCAFAGMALLMTGMALLHMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQPLTSFFSLSLLLVVMAAALDVLANLLLAKSGGFRRRWLGFFSLVLVGLAFYCLSLAVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HMDLAVAYAMWGSFGILGTSLGGWLFFSQKLRPCAFAGMALLMTGMALLHMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]