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The map label for this gene is glnP [H]

Identifier: 220905024

GI number: 220905024

Start: 2127555

End: 2128223

Strand: Direct

Name: glnP [H]

Synonym: Ddes_1761

Alternate gene names: 220905024

Gene position: 2127555-2128223 (Clockwise)

Preceding gene: 220905023

Following gene: 220905025

Centisome position: 74.04

GC content: 60.39

Gene sequence:

>669_bases
GTGCTGGATACGGCCTTTTTCAGCCACGAGCTTATCCCCGCCCTTAACAAGGGGCTGCTCGTATCCCTGGCGCTCATCAT
TCCTGCAGGCAGCCTGGGCTTTGTGGGCGGTGTGCTGCTGGGCTGCGCCCGCGCCTTCGGCCCGCGCTGGATGCGCCGCC
TGGGTGACTGGTTTACCGCCATCGTACGTGGTGTGCCGCTGCTCGTGCAATTGATGATGATCTATTACGCCCTGCCCAAA
CTCGGCATTTATTTTCCGCCATACGGGGCCGCCCTTACAAGCTTTATCCTGTGCACGGCAGCCTACCAGAGCGAATATGT
GCGCGGGGCGCTGCTCTCCATCCGCCAGGGGCAGATACGGGCCGCCCAGGCTCTGGGATTCAGCACCTGGAAAACGGTGG
CCTGGATAGTCGTGCCGCAAGCGGCGCGGCGCGCTCTTCCCGGCTGCGGCAACGAGATCATCTACCTTATCAAGTACAGT
TCACTGGCCTACTTCGTCACCTGCATGGAACTTATGGGCGAGGGCAAGGTTGTGGCGTCAGACACATTCCGCTTTACCGA
AGTGTTCATAACAGTGGGGGCCTACTACCTGGCCATGGTCACCCTGGCGACATTTTTTCTCCGCTGGCTTGAGCGCCGCT
TTCATGTCCCCGGCTTTGGCGCACGATAA

Upstream 100 bases:

>100_bases
AAGCTGATTGAACAGGGCGCGCCCGATGTGCTCCTGGCCGAAGGCTCCACCACACGCACCCGCGACTTCTGCCAACGCCT
GCTGGAGATGGGGGTTTAGC

Downstream 100 bases:

>100_bases
AAAGCCCTTTCTTTCCCGCAACGGAAAGGCTCTCCACTGGTGTACGGTGGAGAGCCTTTTTTGACAGCGCAGGGCAACCC
CTGCAGGCATGCACACATTC

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MLDTAFFSHELIPALNKGLLVSLALIIPAGSLGFVGGVLLGCARAFGPRWMRRLGDWFTAIVRGVPLLVQLMMIYYALPK
LGIYFPPYGAALTSFILCTAAYQSEYVRGALLSIRQGQIRAAQALGFSTWKTVAWIVVPQAARRALPGCGNEIIYLIKYS
SLAYFVTCMELMGEGKVVASDTFRFTEVFITVGAYYLAMVTLATFFLRWLERRFHVPGFGAR

Sequences:

>Translated_222_residues
MLDTAFFSHELIPALNKGLLVSLALIIPAGSLGFVGGVLLGCARAFGPRWMRRLGDWFTAIVRGVPLLVQLMMIYYALPK
LGIYFPPYGAALTSFILCTAAYQSEYVRGALLSIRQGQIRAAQALGFSTWKTVAWIVVPQAARRALPGCGNEIIYLIKYS
SLAYFVTCMELMGEGKVVASDTFRFTEVFITVGAYYLAMVTLATFFLRWLERRFHVPGFGAR
>Mature_222_residues
MLDTAFFSHELIPALNKGLLVSLALIIPAGSLGFVGGVLLGCARAFGPRWMRRLGDWFTAIVRGVPLLVQLMMIYYALPK
LGIYFPPYGAALTSFILCTAAYQSEYVRGALLSIRQGQIRAAQALGFSTWKTVAWIVVPQAARRALPGCGNEIIYLIKYS
SLAYFVTCMELMGEGKVVASDTFRFTEVFITVGAYYLAMVTLATFFLRWLERRFHVPGFGAR

Specific function: Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=207, Percent_Identity=36.231884057971, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788226, Length=213, Percent_Identity=35.6807511737089, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=31.7757009345794, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788645, Length=210, Percent_Identity=30, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788646, Length=211, Percent_Identity=27.9620853080569, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786874, Length=215, Percent_Identity=26.9767441860465, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786873, Length=215, Percent_Identity=26.9767441860465, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082239, Length=220, Percent_Identity=31.3636363636364, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787087, Length=183, Percent_Identity=27.3224043715847, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24587; Mature: 24587

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTAFFSHELIPALNKGLLVSLALIIPAGSLGFVGGVLLGCARAFGPRWMRRLGDWFTA
CCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IVRGVPLLVQLMMIYYALPKLGIYFPPYGAALTSFILCTAAYQSEYVRGALLSIRQGQIR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AAQALGFSTWKTVAWIVVPQAARRALPGCGNEIIYLIKYSSLAYFVTCMELMGEGKVVAS
HHHHHCHHHHHHHHHEEECHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCEEEC
DTFRFTEVFITVGAYYLAMVTLATFFLRWLERRFHVPGFGAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLDTAFFSHELIPALNKGLLVSLALIIPAGSLGFVGGVLLGCARAFGPRWMRRLGDWFTA
CCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IVRGVPLLVQLMMIYYALPKLGIYFPPYGAALTSFILCTAAYQSEYVRGALLSIRQGQIR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AAQALGFSTWKTVAWIVVPQAARRALPGCGNEIIYLIKYSSLAYFVTCMELMGEGKVVAS
HHHHHCHHHHHHHHHEEECHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCEEEC
DTFRFTEVFITVGAYYLAMVTLATFFLRWLERRFHVPGFGAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]