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The map label for this gene is secA

Identifier: 220904973

GI number: 220904973

Start: 2063734

End: 2066310

Strand: Direct

Name: secA

Synonym: Ddes_1709

Alternate gene names: 220904973

Gene position: 2063734-2066310 (Clockwise)

Preceding gene: 220904972

Following gene: 220904983

Centisome position: 71.82

GC content: 57.86

Gene sequence:

>2577_bases
ATGTTCGGCTTTCTTTTCAAAAAAATATTCGGCAGCAAGAACGACCGGTATCTGCGCCGTCTGCGCTCCCAGGTACAGAG
CATCAATGCTCTTGAGCCTCAAATGCAGGAACTGGCGGACGAAGACTTTGCCGCCCGCATCCTCCAGTACAAAAAGGCCG
TGCAGGAAGACGGCCAGAGCCTTGATGCCCTGCTGCCCGAAGTATTCGCCCTGGTGCGCGAAGCATCGCGACGCGTGCTC
GGCATGCGCCACTATGATATGCAGCTTATAGGTGGCATGGTGCTGCACAAGGGCAAGATCGCCGAAATGAAAACAGGCGA
AGGCAAAACCCTGGTCGCCACACTGCCCGTGGTACTCAACGCCCTGTCGGGCAAGGGTGTGCATGTGGTCACGGTCAACG
ACTATCTGGCCAAGCGTGACGCGGCCTGGATGGGTCAGCTTTACGGTTTCCTGGGGCTGAGCACAGGCGTCATCGTTCAC
GGCCTGGACGACGACGAGCGCAAGCAGCAGTACGAATCTGATATTACCTACGGCACCAACAACGAATTCGGCTTTGACTA
CCTGCGCGACAACATGAAGTTTTATGGGCACCAGCTGGTACAGCGCGGGCACAACTATGCCATCGTTGACGAAGTGGACT
CCATCCTTATTGACGAAGCCCGTACGCCCCTCATCATTTCCGGCGCGTCCGACGAATCGGTGGGCATGTACCGGATTGTG
GACGAGGTGGTGTGCAAGCTGCGGCCCGAACACTATACCGTAGACGAAAAAGCCCGCACCGCCATGCTCACCGATGAGGG
CGTGGCCTACTGCGAAGAGATGCTCAAACTGGATAATCTGTTTGATCCCGCCAACATCACCGCACAGCACCACGTGCTGC
AATCGCTCAAAGCCCATCAGGTGTTCAAGCGCGATGTGGACTACATTGTGCAGGACGATCAGGTCGTAATTGTTGACGAA
TTTACCGGCCGCCTCATGGCGGGCCGCCGCTATTCCGATGGACTGCACCAGGCACTGGAGGCCAAGGAAGGCGTGACCAT
CGCCGCCGAAAACCAGACCCTCGCCTCCATCACCTTCCAGAACTATTTTCGTCTGTACGACAAGCTTTCAGGCATGACGG
GTACAGCCGACACAGAAGCCGTGGAATTTCACCAGATATACAATCTGGAAGTTATTTCCATTCCGCCCAACCGGCCCATG
CAGCGCAAGGACTATCCCGACCTCATCTACCGCAGCCGTCAGGAAAAATTCGACGCCATTGTCGAGGCCATCACCGAACT
GCATAAAAACCGCCAGCCTGTTCTGGTGGGGACAATTTCCATCGAAACGTCCGAAATGCTTTCACATCGCCTGAGCAAGC
TCGGGGTCCCCCACAACGTGCTCAATGCCAAGCAACATGAAAAAGAAGCGGAAATCGTGGCCCAGGCCGGCCAGCCCGGC
AAAGTCACCATTGCCACCAACATGGCCGGGCGCGGTACGGACATTGTGCTTGGCGAAGGCGTAGTGGACCTGGGCGGCCT
GCATATCCTCGGAACAGAAAGACACGAAAGCCGCCGCATCGACAACCAGTTGCGCGGGCGCTCCGGACGTCAGGGCGACC
CCGGCTCCTCACGTTTCTACCTGTCGCTTGAAGATGACCTCATGCGCCTCTTCGGTTCTGACCGCATCAAGGGCCTGATG
GAAAAACTGGGGCTGCGTGACGGCGAAGCCATTGAAAACGCCATGGTCACCCGCGCGGTTGAGGGCGCACAAAAACGCGT
GGAAGCCCATCACTTTGAGGTCCGCAAAACCCTGCTGGACTATGACAACGTCATGAACCAGCAGCGCGAGGTCATCTACG
CCCTGCGCCGTGAGCTTATGGTTGAGGAAGACCTTGACCCGGTGATGGACGAATTCATGAACGACGTGCTTGATGACGTG
TACAGCACACTGGACGGCGTGCCTGTAGACGATCACAACGGCCTGCGTGAAGCCGCCTTCGCCCGCCTGCGCGATGTCTT
CAACCTGGACCGCGTACTGCCCGAAAATGCGCACCTGCCCGAACGTGAGGAATGTGAACCCCTGATACGTAAGGTACTGG
AAGAGCTGCGCTCTGAAACCGGCGACAGTTACCGCGACATCCAGCGCTACTTTATGCTGGAAGAACTCGACCGCTGCTGG
AAAGAACACCTGCGCAACATGGACGCCCTGCGCGACGGCATCGGCCTGCGCGGCTACGGCCAGCGTGACCCCAAACTGGA
ATACAAGCGCGAAGGCTTTGAAATGTTTCAGGCCATGCTGTTCCAGATTCGCGAAAACGTGTTCCGCGCTCTCAGCCGTG
TGCGTGTAGCCCCGGCTGAAACCGCGCCCGTGGAAGCCATAGAGATCGCTCCGGAAACTGAAGAAGCTCAGGGCCAGCCC
CTGGCGCGTGAATACCGCCACAAGGAAGACAGGGGCCAGCTCTCCTATTCCGGCGGCGGCAATGCCGAAGATGCACGCAA
TACCCCGGCAAAGGCCGCTCCCCGCATTGGCCGGAATGATCCCTGCCCCTGCGGCAGCGGCAGAAAATATAAAAAATGTT
GCGGTGCGGACAAGTAA

Upstream 100 bases:

>100_bases
AGGCTGCCCGGAACTACGTTTTCAGAGCAGCCCCAGTGCGCCGCGTTGTCGCGCTGGCCGGGCAAAGGCGGTTTGCCCCG
CGCCCAACAGAGGAGACTTC

Downstream 100 bases:

>100_bases
TGCCTGGCAGCCTGCAAGAACGGCTGCCGTGATTCCTGCCGCAGGCATTTGAAAAGAGCGGTTCCCCACAAGGGGAACCG
CTCTTTTACTGTATGTTCTC

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 858; Mature: 858

Protein sequence:

>858_residues
MFGFLFKKIFGSKNDRYLRRLRSQVQSINALEPQMQELADEDFAARILQYKKAVQEDGQSLDALLPEVFALVREASRRVL
GMRHYDMQLIGGMVLHKGKIAEMKTGEGKTLVATLPVVLNALSGKGVHVVTVNDYLAKRDAAWMGQLYGFLGLSTGVIVH
GLDDDERKQQYESDITYGTNNEFGFDYLRDNMKFYGHQLVQRGHNYAIVDEVDSILIDEARTPLIISGASDESVGMYRIV
DEVVCKLRPEHYTVDEKARTAMLTDEGVAYCEEMLKLDNLFDPANITAQHHVLQSLKAHQVFKRDVDYIVQDDQVVIVDE
FTGRLMAGRRYSDGLHQALEAKEGVTIAAENQTLASITFQNYFRLYDKLSGMTGTADTEAVEFHQIYNLEVISIPPNRPM
QRKDYPDLIYRSRQEKFDAIVEAITELHKNRQPVLVGTISIETSEMLSHRLSKLGVPHNVLNAKQHEKEAEIVAQAGQPG
KVTIATNMAGRGTDIVLGEGVVDLGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRLFGSDRIKGLM
EKLGLRDGEAIENAMVTRAVEGAQKRVEAHHFEVRKTLLDYDNVMNQQREVIYALRRELMVEEDLDPVMDEFMNDVLDDV
YSTLDGVPVDDHNGLREAAFARLRDVFNLDRVLPENAHLPEREECEPLIRKVLEELRSETGDSYRDIQRYFMLEELDRCW
KEHLRNMDALRDGIGLRGYGQRDPKLEYKREGFEMFQAMLFQIRENVFRALSRVRVAPAETAPVEAIEIAPETEEAQGQP
LAREYRHKEDRGQLSYSGGGNAEDARNTPAKAAPRIGRNDPCPCGSGRKYKKCCGADK

Sequences:

>Translated_858_residues
MFGFLFKKIFGSKNDRYLRRLRSQVQSINALEPQMQELADEDFAARILQYKKAVQEDGQSLDALLPEVFALVREASRRVL
GMRHYDMQLIGGMVLHKGKIAEMKTGEGKTLVATLPVVLNALSGKGVHVVTVNDYLAKRDAAWMGQLYGFLGLSTGVIVH
GLDDDERKQQYESDITYGTNNEFGFDYLRDNMKFYGHQLVQRGHNYAIVDEVDSILIDEARTPLIISGASDESVGMYRIV
DEVVCKLRPEHYTVDEKARTAMLTDEGVAYCEEMLKLDNLFDPANITAQHHVLQSLKAHQVFKRDVDYIVQDDQVVIVDE
FTGRLMAGRRYSDGLHQALEAKEGVTIAAENQTLASITFQNYFRLYDKLSGMTGTADTEAVEFHQIYNLEVISIPPNRPM
QRKDYPDLIYRSRQEKFDAIVEAITELHKNRQPVLVGTISIETSEMLSHRLSKLGVPHNVLNAKQHEKEAEIVAQAGQPG
KVTIATNMAGRGTDIVLGEGVVDLGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRLFGSDRIKGLM
EKLGLRDGEAIENAMVTRAVEGAQKRVEAHHFEVRKTLLDYDNVMNQQREVIYALRRELMVEEDLDPVMDEFMNDVLDDV
YSTLDGVPVDDHNGLREAAFARLRDVFNLDRVLPENAHLPEREECEPLIRKVLEELRSETGDSYRDIQRYFMLEELDRCW
KEHLRNMDALRDGIGLRGYGQRDPKLEYKREGFEMFQAMLFQIRENVFRALSRVRVAPAETAPVEAIEIAPETEEAQGQP
LAREYRHKEDRGQLSYSGGGNAEDARNTPAKAAPRIGRNDPCPCGSGRKYKKCCGADK
>Mature_858_residues
MFGFLFKKIFGSKNDRYLRRLRSQVQSINALEPQMQELADEDFAARILQYKKAVQEDGQSLDALLPEVFALVREASRRVL
GMRHYDMQLIGGMVLHKGKIAEMKTGEGKTLVATLPVVLNALSGKGVHVVTVNDYLAKRDAAWMGQLYGFLGLSTGVIVH
GLDDDERKQQYESDITYGTNNEFGFDYLRDNMKFYGHQLVQRGHNYAIVDEVDSILIDEARTPLIISGASDESVGMYRIV
DEVVCKLRPEHYTVDEKARTAMLTDEGVAYCEEMLKLDNLFDPANITAQHHVLQSLKAHQVFKRDVDYIVQDDQVVIVDE
FTGRLMAGRRYSDGLHQALEAKEGVTIAAENQTLASITFQNYFRLYDKLSGMTGTADTEAVEFHQIYNLEVISIPPNRPM
QRKDYPDLIYRSRQEKFDAIVEAITELHKNRQPVLVGTISIETSEMLSHRLSKLGVPHNVLNAKQHEKEAEIVAQAGQPG
KVTIATNMAGRGTDIVLGEGVVDLGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRLFGSDRIKGLM
EKLGLRDGEAIENAMVTRAVEGAQKRVEAHHFEVRKTLLDYDNVMNQQREVIYALRRELMVEEDLDPVMDEFMNDVLDDV
YSTLDGVPVDDHNGLREAAFARLRDVFNLDRVLPENAHLPEREECEPLIRKVLEELRSETGDSYRDIQRYFMLEELDRCW
KEHLRNMDALRDGIGLRGYGQRDPKLEYKREGFEMFQAMLFQIRENVFRALSRVRVAPAETAPVEAIEIAPETEEAQGQP
LAREYRHKEDRGQLSYSGGGNAEDARNTPAKAAPRIGRNDPCPCGSGRKYKKCCGADK

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=922, Percent_Identity=52.1691973969631, Blast_Score=877, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_DESDA (B8J1J9)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002480285.1
- GeneID:   7285420
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1709
- HOGENOM:   HBG284200
- ProtClustDB:   PRK12904
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 97281; Mature: 97281

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFLFKKIFGSKNDRYLRRLRSQVQSINALEPQMQELADEDFAARILQYKKAVQEDGQS
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCH
LDALLPEVFALVREASRRVLGMRHYDMQLIGGMVLHKGKIAEMKTGEGKTLVATLPVVLN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHH
ALSGKGVHVVTVNDYLAKRDAAWMGQLYGFLGLSTGVIVHGLDDDERKQQYESDITYGTN
HHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCCC
NEFGFDYLRDNMKFYGHQLVQRGHNYAIVDEVDSILIDEARTPLIISGASDESVGMYRIV
CCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHH
DEVVCKLRPEHYTVDEKARTAMLTDEGVAYCEEMLKLDNLFDPANITAQHHVLQSLKAHQ
HHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VFKRDVDYIVQDDQVVIVDEFTGRLMAGRRYSDGLHQALEAKEGVTIAAENQTLASITFQ
HHHHHHHHEECCCCEEEEECCCCHHHCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHH
NYFRLYDKLSGMTGTADTEAVEFHQIYNLEVISIPPNRPMQRKDYPDLIYRSRQEKFDAI
HHHHHHHHHCCCCCCCCCHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
VEAITELHKNRQPVLVGTISIETSEMLSHRLSKLGVPHNVLNAKQHEKEAEIVAQAGQPG
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHCCCCC
KVTIATNMAGRGTDIVLGEGVVDLGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFY
EEEEEECCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCEEE
LSLEDDLMRLFGSDRIKGLMEKLGLRDGEAIENAMVTRAVEGAQKRVEAHHFEVRKTLLD
EEEHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDNVMNQQREVIYALRRELMVEEDLDPVMDEFMNDVLDDVYSTLDGVPVDDHNGLREAAF
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
ARLRDVFNLDRVLPENAHLPEREECEPLIRKVLEELRSETGDSYRDIQRYFMLEELDRCW
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KEHLRNMDALRDGIGLRGYGQRDPKLEYKREGFEMFQAMLFQIRENVFRALSRVRVAPAE
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TAPVEAIEIAPETEEAQGQPLAREYRHKEDRGQLSYSGGGNAEDARNTPAKAAPRIGRND
CCCCCEEEECCCCCCCCCCCHHHHHCCCHHCCCEEECCCCCCCCCCCCCCHHCCCCCCCC
PCPCGSGRKYKKCCGADK
CCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MFGFLFKKIFGSKNDRYLRRLRSQVQSINALEPQMQELADEDFAARILQYKKAVQEDGQS
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCH
LDALLPEVFALVREASRRVLGMRHYDMQLIGGMVLHKGKIAEMKTGEGKTLVATLPVVLN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHH
ALSGKGVHVVTVNDYLAKRDAAWMGQLYGFLGLSTGVIVHGLDDDERKQQYESDITYGTN
HHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCCC
NEFGFDYLRDNMKFYGHQLVQRGHNYAIVDEVDSILIDEARTPLIISGASDESVGMYRIV
CCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHH
DEVVCKLRPEHYTVDEKARTAMLTDEGVAYCEEMLKLDNLFDPANITAQHHVLQSLKAHQ
HHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VFKRDVDYIVQDDQVVIVDEFTGRLMAGRRYSDGLHQALEAKEGVTIAAENQTLASITFQ
HHHHHHHHEECCCCEEEEECCCCHHHCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHH
NYFRLYDKLSGMTGTADTEAVEFHQIYNLEVISIPPNRPMQRKDYPDLIYRSRQEKFDAI
HHHHHHHHHCCCCCCCCCHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
VEAITELHKNRQPVLVGTISIETSEMLSHRLSKLGVPHNVLNAKQHEKEAEIVAQAGQPG
HHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHCCCCC
KVTIATNMAGRGTDIVLGEGVVDLGGLHILGTERHESRRIDNQLRGRSGRQGDPGSSRFY
EEEEEECCCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCEEE
LSLEDDLMRLFGSDRIKGLMEKLGLRDGEAIENAMVTRAVEGAQKRVEAHHFEVRKTLLD
EEEHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDNVMNQQREVIYALRRELMVEEDLDPVMDEFMNDVLDDVYSTLDGVPVDDHNGLREAAF
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
ARLRDVFNLDRVLPENAHLPEREECEPLIRKVLEELRSETGDSYRDIQRYFMLEELDRCW
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KEHLRNMDALRDGIGLRGYGQRDPKLEYKREGFEMFQAMLFQIRENVFRALSRVRVAPAE
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TAPVEAIEIAPETEEAQGQPLAREYRHKEDRGQLSYSGGGNAEDARNTPAKAAPRIGRND
CCCCCEEEECCCCCCCCCCCHHHHHCCCHHCCCEEECCCCCCCCCCCCCCHHCCCCCCCC
PCPCGSGRKYKKCCGADK
CCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA