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The map label for this gene is nuoA2 [H]

Identifier: 220904930

GI number: 220904930

Start: 2001379

End: 2001753

Strand: Reverse

Name: nuoA2 [H]

Synonym: Ddes_1665

Alternate gene names: 220904930

Gene position: 2001753-2001379 (Counterclockwise)

Preceding gene: 220904931

Following gene: 220904929

Centisome position: 69.66

GC content: 49.87

Gene sequence:

>375_bases
ATGGTGCATACAACAGCCGGTCAAGAATATCTTGCCGTACTGCTGCTCATTATCATCACACTGCTTTTTGGTCTGATCAC
GCTTTTTGTGGGGCGCTTTTTCCGCATGAGCAGGCCTTATCCGGAAAAGCTTGTGGCCTATGAATCGGGCAACGAACCTA
CGGCTGAACCGCGAACGCGTTTTTCCATCAAGTTTTATTACGTAGCTATACTGTTTGTCATTATCGATGTGGAGGCCATC
TATCTTTATACCTGGGCCGTGGAGTTTGTGCGCCTTGGCAGCCTTGGCATGGTGGAGATGTTCACCTTTATGGCTCTGCT
GGTTCTCGGCTACCTGTATGCCTGGAAGAAGGGGGCGTTCCAATGGGTGAAGTAG

Upstream 100 bases:

>100_bases
CACAAAGGCGCGCCTCTGTGCCGGAAGCGCGGCTCACGAAGCCCGGCAACGTCCGGTGCGGTGAAAGCGAAAAATTGTGA
AGGAAAGCAAGGTGGCTACC

Downstream 100 bases:

>100_bases
TCACAAAGTCCGGGGGGGCTGTGCACACCGGCGGGCAGCCCCTTGAGGTCAGTAAGGACGGCCTGCGTTTTTTTCCCGGC
GCAGGCGCTGTTATCGGGCC

Product: NADH-ubiquinone/plastoquinone oxidoreductase chain 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 2; NDH-1 subunit A 2; NUO1 2 [H]

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MVHTTAGQEYLAVLLLIIITLLFGLITLFVGRFFRMSRPYPEKLVAYESGNEPTAEPRTRFSIKFYYVAILFVIIDVEAI
YLYTWAVEFVRLGSLGMVEMFTFMALLVLGYLYAWKKGAFQWVK

Sequences:

>Translated_124_residues
MVHTTAGQEYLAVLLLIIITLLFGLITLFVGRFFRMSRPYPEKLVAYESGNEPTAEPRTRFSIKFYYVAILFVIIDVEAI
YLYTWAVEFVRLGSLGMVEMFTFMALLVLGYLYAWKKGAFQWVK
>Mature_124_residues
MVHTTAGQEYLAVLLLIIITLLFGLITLFVGRFFRMSRPYPEKLVAYESGNEPTAEPRTRFSIKFYYVAILFVIIDVEAI
YLYTWAVEFVRLGSLGMVEMFTFMALLVLGYLYAWKKGAFQWVK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=112, Percent_Identity=37.5, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 14398; Mature: 14398

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHTTAGQEYLAVLLLIIITLLFGLITLFVGRFFRMSRPYPEKLVAYESGNEPTAEPRTR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCHH
FSIKFYYVAILFVIIDVEAIYLYTWAVEFVRLGSLGMVEMFTFMALLVLGYLYAWKKGAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QWVK
CCCC
>Mature Secondary Structure
MVHTTAGQEYLAVLLLIIITLLFGLITLFVGRFFRMSRPYPEKLVAYESGNEPTAEPRTR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCHH
FSIKFYYVAILFVIIDVEAIYLYTWAVEFVRLGSLGMVEMFTFMALLVLGYLYAWKKGAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QWVK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA