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The map label for this gene is blh [H]

Identifier: 220904912

GI number: 220904912

Start: 1981686

End: 1982555

Strand: Direct

Name: blh [H]

Synonym: Ddes_1647

Alternate gene names: 220904912

Gene position: 1981686-1982555 (Clockwise)

Preceding gene: 220904911

Following gene: 220904913

Centisome position: 68.97

GC content: 56.44

Gene sequence:

>870_bases
ATGACTGCCCCCAATGTGCGCGGATTTTTTGACCCCGTTACCGCAACCTGGACCTATGTGGTCTGGTCCGGTACAGACAG
CCGCCGGCGCTGCGCCATTATCGACAGCGTGCTGGACTATGACATGCCCTCAAGCCGCACCGGCACGGCATCCGCAGATA
CGGTTATTACATTTGTACACCGGAAAGAGCTTGAGGTAGAGTGGATACTTGAAACACACATTCATGCGGACCATATTACC
GCCGCCCGCTACCTCAAGGAAAGGCTGGGCGGCAAGATAGCCATGAGCAGGCACATGCTGAATATCATCGCCACCTGGGT
TCCCGTTTTTCAGACCGGCGACGATACCCCGGCCGATGGAGCAGATTTTGACCATCTTTTTGAAAACGATGAAACATTCA
CCATTGGTGACCTCAAGGCCAAAATCATCCATACGCCCGGGCATACCCCGGCCGACACCACCTACATCATCGAAGATGCC
GCCTTTGTGGGCGACACCATCTTTCTGCCCGACGTGGGTTCCGGCCGCTGCGATTTCCCGGGCGGCAGCCCCGAGGACTC
CTACGAATCTTCGCGCAAACTTTTTGCCCTGCCGGACCATTACCGCATATATGTGGGACACGACTATCCCCCGGCAGGCA
AACGCGGCCCCGAGTGCATGAGCACCGTCGGCGAACAAAAGCTGAAAAATGAACGCCTGCACATGGGCATTGATAAAAAC
AGCTTCGTCTCGCGCCGTAAGGCAGATGATACGGGCAAGGCCGTGCCGCCTCTGCTGCTGCCCTCCATCCAGGCCAATAT
GCGCGCAGGCGACTTTGGCGCACCAACTGGAGGCATTCAGTACGTAAAATTGCCGGTAAACAAGATCTAG

Upstream 100 bases:

>100_bases
CGCAGTGCCGGATCAAAGCCCGGCACGCCGGATATTCACGGTTGGGCCAGTTCCAACCCTACAGCGCCGCCAGGCGCAAC
CGACGCCCAAGGAGACTATT

Downstream 100 bases:

>100_bases
CCGGAATACATACATTTTGCCATGAAGGCCCTGATGCCCGGGCCTTCATGGCATTGTCATTTTATGAAAGCCGTGTCATA
TTGTGAGCAATAGCTATTAC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTAPNVRGFFDPVTATWTYVVWSGTDSRRRCAIIDSVLDYDMPSSRTGTASADTVITFVHRKELEVEWILETHIHADHIT
AARYLKERLGGKIAMSRHMLNIIATWVPVFQTGDDTPADGADFDHLFENDETFTIGDLKAKIIHTPGHTPADTTYIIEDA
AFVGDTIFLPDVGSGRCDFPGGSPEDSYESSRKLFALPDHYRIYVGHDYPPAGKRGPECMSTVGEQKLKNERLHMGIDKN
SFVSRRKADDTGKAVPPLLLPSIQANMRAGDFGAPTGGIQYVKLPVNKI

Sequences:

>Translated_289_residues
MTAPNVRGFFDPVTATWTYVVWSGTDSRRRCAIIDSVLDYDMPSSRTGTASADTVITFVHRKELEVEWILETHIHADHIT
AARYLKERLGGKIAMSRHMLNIIATWVPVFQTGDDTPADGADFDHLFENDETFTIGDLKAKIIHTPGHTPADTTYIIEDA
AFVGDTIFLPDVGSGRCDFPGGSPEDSYESSRKLFALPDHYRIYVGHDYPPAGKRGPECMSTVGEQKLKNERLHMGIDKN
SFVSRRKADDTGKAVPPLLLPSIQANMRAGDFGAPTGGIQYVKLPVNKI
>Mature_288_residues
TAPNVRGFFDPVTATWTYVVWSGTDSRRRCAIIDSVLDYDMPSSRTGTASADTVITFVHRKELEVEWILETHIHADHITA
ARYLKERLGGKIAMSRHMLNIIATWVPVFQTGDDTPADGADFDHLFENDETFTIGDLKAKIIHTPGHTPADTTYIIEDAA
FVGDTIFLPDVGSGRCDFPGGSPEDSYESSRKLFALPDHYRIYVGHDYPPAGKRGPECMSTVGEQKLKNERLHMGIDKNS
FVSRRKADDTGKAVPPLLLPSIQANMRAGDFGAPTGGIQYVKLPVNKI

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=269, Percent_Identity=28.996282527881, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538952, Length=273, Percent_Identity=29.6703296703297, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221330176, Length=272, Percent_Identity=29.0441176470588, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24667703, Length=165, Percent_Identity=35.1515151515151, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356335, Length=165, Percent_Identity=35.1515151515151, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667711, Length=165, Percent_Identity=35.1515151515151, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31953; Mature: 31822

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPNVRGFFDPVTATWTYVVWSGTDSRRRCAIIDSVLDYDMPSSRTGTASADTVITFVH
CCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEE
RKELEVEWILETHIHADHITAARYLKERLGGKIAMSRHMLNIIATWVPVFQTGDDTPADG
CCCCEEEEEEECCCCHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHEECCCCCCCCC
ADFDHLFENDETFTIGDLKAKIIHTPGHTPADTTYIIEDAAFVGDTIFLPDVGSGRCDFP
CCHHHHHCCCCEEEEECEEEEEEECCCCCCCCCEEEEECHHHHCCEEEECCCCCCCCCCC
GGSPEDSYESSRKLFALPDHYRIYVGHDYPPAGKRGPECMSTVGEQKLKNERLHMGIDKN
CCCCCCCHHCCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCH
SFVSRRKADDTGKAVPPLLLPSIQANMRAGDFGAPTGGIQYVKLPVNKI
HHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TAPNVRGFFDPVTATWTYVVWSGTDSRRRCAIIDSVLDYDMPSSRTGTASADTVITFVH
CCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEE
RKELEVEWILETHIHADHITAARYLKERLGGKIAMSRHMLNIIATWVPVFQTGDDTPADG
CCCCEEEEEEECCCCHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHEECCCCCCCCC
ADFDHLFENDETFTIGDLKAKIIHTPGHTPADTTYIIEDAAFVGDTIFLPDVGSGRCDFP
CCHHHHHCCCCEEEEECEEEEEEECCCCCCCCCEEEEECHHHHCCEEEECCCCCCCCCCC
GGSPEDSYESSRKLFALPDHYRIYVGHDYPPAGKRGPECMSTVGEQKLKNERLHMGIDKN
CCCCCCCHHCCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCH
SFVSRRKADDTGKAVPPLLLPSIQANMRAGDFGAPTGGIQYVKLPVNKI
HHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]