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The map label for this gene is ttdA [C]

Identifier: 220904796

GI number: 220904796

Start: 1825624

End: 1826469

Strand: Direct

Name: ttdA [C]

Synonym: Ddes_1528

Alternate gene names: 220904796

Gene position: 1825624-1826469 (Clockwise)

Preceding gene: 220904795

Following gene: 220904797

Centisome position: 63.53

GC content: 61.23

Gene sequence:

>846_bases
ATGAAGGAAATCCATTTTGACGACATAGCATGCACTGTGGCGGAACTGGCCATAGAAGCCTGCTACCGCCTGCCGGACGA
CATGGTTGCGGCCATGCGCGCGGCACGAACGCGCGAACCATCGCCCGTGGGGCGTAACATCCTGGATCAACTGCTGGAAA
ATGCTGAAATCGCCGCCAGGGGCGATCTGCCCCTGTGCCAGGATACCGGCCTTGCCGTAATTTTTGCCGAAGTGGGCCAG
GATGTGCGCATTGTGGGCGGCTCTTTTGAAGATGCCATCAATGAAGGCATTCGCAAGGGGTATACAGAGGGCTACCTGCG
CAAATCCTGTGTGGACGAGCCGCTGTTTGAGCGCAAAAACACCAAAGACAACACTCCTGCCGTCATCCATACCCGCCTTG
TCCCCGGCAGCGGGCTGCGCCTGCGGCTGGCCCCCAAGGGGGCAGGGTCGGAAAACAAGAGTGTGCTCAAGATGCTCGTA
CCGGCAGACGGCATCGAGGGCGTGCGCCAGGTGGTTCTGGACGCAGTCCTGGCCGCCGGACCCAACTCCTGTCCGCCCCT
CGTCATCGGCGTCGGCATCGGCGGCACGATGGAAATGGCCGCCATATGCGCCAAACGCGCAGCCGCCCGCGACCTTGAAA
GCCGCAACCACGATCCGCGCTATGCGGCCTTTGAAGATGAACTGCTGGAAATGGTCAACAAAACCGGCGTAGGCCCCCAA
GGACTGGGCGGCATTACTACCGCCCTCAAGGTACATGTGGAATGGGCGCCGACCCATATCGCCTCTTTGCCGGTCGCCGT
AAATATCAACTGCCACGCGGCGCGCCACGCCGAAGCCGTGCTGTAA

Upstream 100 bases:

>100_bases
TATCCCCCTGATCTGGCCTTTCCATTAGGCTGCCGTCAGGTGCGCTGTGGCCATGGGCGCCACAGCAGTTAATGCTGATA
AAGAACGGGACGGTGTGGAC

Downstream 100 bases:

>100_bases
GGGGGAGCCATGTCTGACGAAATCAAAAAAATCCGCGCTCCCTTTGATGAAGCCACTGCCCGCTCACTGCGCGCTGGAGA
CCGTGTTCTTATTTCCGGCA

Product: hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit alpha

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKEIHFDDIACTVAELAIEACYRLPDDMVAAMRAARTREPSPVGRNILDQLLENAEIAARGDLPLCQDTGLAVIFAEVGQ
DVRIVGGSFEDAINEGIRKGYTEGYLRKSCVDEPLFERKNTKDNTPAVIHTRLVPGSGLRLRLAPKGAGSENKSVLKMLV
PADGIEGVRQVVLDAVLAAGPNSCPPLVIGVGIGGTMEMAAICAKRAAARDLESRNHDPRYAAFEDELLEMVNKTGVGPQ
GLGGITTALKVHVEWAPTHIASLPVAVNINCHAARHAEAVL

Sequences:

>Translated_281_residues
MKEIHFDDIACTVAELAIEACYRLPDDMVAAMRAARTREPSPVGRNILDQLLENAEIAARGDLPLCQDTGLAVIFAEVGQ
DVRIVGGSFEDAINEGIRKGYTEGYLRKSCVDEPLFERKNTKDNTPAVIHTRLVPGSGLRLRLAPKGAGSENKSVLKMLV
PADGIEGVRQVVLDAVLAAGPNSCPPLVIGVGIGGTMEMAAICAKRAAARDLESRNHDPRYAAFEDELLEMVNKTGVGPQ
GLGGITTALKVHVEWAPTHIASLPVAVNINCHAARHAEAVL
>Mature_281_residues
MKEIHFDDIACTVAELAIEACYRLPDDMVAAMRAARTREPSPVGRNILDQLLENAEIAARGDLPLCQDTGLAVIFAEVGQ
DVRIVGGSFEDAINEGIRKGYTEGYLRKSCVDEPLFERKNTKDNTPAVIHTRLVPGSGLRLRLAPKGAGSENKSVLKMLV
PADGIEGVRQVVLDAVLAAGPNSCPPLVIGVGIGGTMEMAAICAKRAAARDLESRNHDPRYAAFEDELLEMVNKTGVGPQ
GLGGITTALKVHVEWAPTHIASLPVAVNINCHAARHAEAVL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=278, Percent_Identity=29.8561151079137, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790564, Length=253, Percent_Identity=34.7826086956522, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787897, Length=255, Percent_Identity=34.5098039215686, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 29971; Mature: 29971

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIHFDDIACTVAELAIEACYRLPDDMVAAMRAARTREPSPVGRNILDQLLENAEIAAR
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEC
GDLPLCQDTGLAVIFAEVGQDVRIVGGSFEDAINEGIRKGYTEGYLRKSCVDEPLFERKN
CCCCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCC
TKDNTPAVIHTRLVPGSGLRLRLAPKGAGSENKSVLKMLVPADGIEGVRQVVLDAVLAAG
CCCCCCEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCC
PNSCPPLVIGVGIGGTMEMAAICAKRAAARDLESRNHDPRYAAFEDELLEMVNKTGVGPQ
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
GLGGITTALKVHVEWAPTHIASLPVAVNINCHAARHAEAVL
CCCHHEEEEEEEEEECCHHHHHCCEEEEECCCCHHHHHHCC
>Mature Secondary Structure
MKEIHFDDIACTVAELAIEACYRLPDDMVAAMRAARTREPSPVGRNILDQLLENAEIAAR
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEC
GDLPLCQDTGLAVIFAEVGQDVRIVGGSFEDAINEGIRKGYTEGYLRKSCVDEPLFERKN
CCCCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCC
TKDNTPAVIHTRLVPGSGLRLRLAPKGAGSENKSVLKMLVPADGIEGVRQVVLDAVLAAG
CCCCCCEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCC
PNSCPPLVIGVGIGGTMEMAAICAKRAAARDLESRNHDPRYAAFEDELLEMVNKTGVGPQ
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
GLGGITTALKVHVEWAPTHIASLPVAVNINCHAARHAEAVL
CCCHHEEEEEEEEEECCHHHHHCCEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]