Click here to switch to the map view.

The map label for this gene is yegE [C]

Identifier: 220904743

GI number: 220904743

Start: 1764700

End: 1766115

Strand: Direct

Name: yegE [C]

Synonym: Ddes_1475

Alternate gene names: 220904743

Gene position: 1764700-1766115 (Clockwise)

Preceding gene: 220904742

Following gene: 220904744

Centisome position: 61.41

GC content: 59.53

Gene sequence:

>1416_bases
ATGCTGAACAAGTCAAGCATCATACCAGAACATATACAGCTCGAATCACACGACCCTGTCTGGGAGTGGCACACGACATC
CGACAGGCTTTTCATGAGCGTAGGCGCCCTTGCCCAGCTACGCATGGACGGCAAACCGCCGCGCAGCATGAAAGATTATC
TGGAGCACTGCCCCCTCGAAAGCCTGGCTCCCCTTCTTGAATCTATGGAAAAAGCGCTCAACGGCTCCCACGGGCCGCAC
CTTGAAGTGTTTTATCCTTTTGACAGTTTTCTGGTACGGTCTCAGATACTGGTCTTGCGGCGCGACGTTTTCGGTCGCGG
AACCCTGGTAACAGGCTGCAACGTGGCTATGGACAGACAAAGGCTTGCACCCACTGCTGCCGCCGCCCCCGTGCCGGCAC
CCCAGCCCCCGCCCCGAAGCCTGGCCGAAGCCGCCGTTCCTTCCACGGCCCGCAGCGACGCCAGCCGCCTCATGCTGGCC
CTCAACGCCGCCAGCGATGGCCTGTGGGACTGGGACCCCAGCACCAATGCCATTTATTTCAGTCCCCGCTACCTCGACAT
GCTTGGCTACACCAGCGAAGAATTCCCCCCCCTGTCCACATCATGGACCAGCAAGGTACACCCCGACGATTACGACAACA
TCGTTCCCATGCAGATTGAATTCATCAACAACCCCAAAATGGGCGACAGCTTTGAATGCACCTACCGGATGCAGCGCGGC
GACGGCACCTGGGCATGGATTCTCAGCCGGGGCTATGTGACTCACCGCGACGCAAGCGGCAAGGCCATCCGCGTTGTGGG
CCTGCACACAGACGTCAGCGCGAGCCAGGGCGACAGGGCACGGCTTGAAGAGCTGGTGCGTAACGACGCCCTTACCGGGC
TGCGCAGCCGCACCTATTATGGAATGACTGTCGACAAGCTGGAACAGCAGCAGATGCGGCCCGTCAGCATCATCATCGCC
GACATGGACGGACTCAAAATGGTCAACGACCATGTAGGCCATACCGAAGGCAGCGAAATGCTCTGCCAGGCAGCCATCAT
ACTGCGCGGCAGTCTCAATGCCACCGACTGTATCGCCCGCATGGGCGGCGATGAATTTGCCGCCATTGTGCCGGGTTGCG
CCAAGGAAGACCTTGAGGCGCTCATCCAGCGGGTCAGAGACGCTTTTGATGCCTATAATGCCGACCCGGACCATGTGCCG
ACACACATGTCTGTGGGCGGAGCATGCGCTGACGACATGAACACCACCCTGGCCCAGGCCCTGTCGGAGGCGGATCGCAA
CATGCTGGCCGTCAAGCACGAAAGCAGCCCAAAGTGGCGCCTGCGCATAAAAAACTGGATAGAAAACCGGACCGGCAAAA
CAATTCAGCTTGAAGACAGCCGCTACAGGATGTCCCCCACGCACGACGACTCTTGA

Upstream 100 bases:

>100_bases
TTTCCTGCAGGACACATCGAAGGCGGCCAGCCTTCACAAATCAATCCAGAACGTCATCATTCCCACCGATCCTTTGTAAT
AATGGACGGTTGAGATTTTT

Downstream 100 bases:

>100_bases
CGTGGAGCGCACTTTGAGCCAAAGTATGCCCATGTCCGAAGATAACCCTCCCCCTACGCAGGCCCTCGGCGCTTCCGTGA
CGGAAATTCCCGTTGTTCAG

Product: PAS/PAC sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MLNKSSIIPEHIQLESHDPVWEWHTTSDRLFMSVGALAQLRMDGKPPRSMKDYLEHCPLESLAPLLESMEKALNGSHGPH
LEVFYPFDSFLVRSQILVLRRDVFGRGTLVTGCNVAMDRQRLAPTAAAAPVPAPQPPPRSLAEAAVPSTARSDASRLMLA
LNAASDGLWDWDPSTNAIYFSPRYLDMLGYTSEEFPPLSTSWTSKVHPDDYDNIVPMQIEFINNPKMGDSFECTYRMQRG
DGTWAWILSRGYVTHRDASGKAIRVVGLHTDVSASQGDRARLEELVRNDALTGLRSRTYYGMTVDKLEQQQMRPVSIIIA
DMDGLKMVNDHVGHTEGSEMLCQAAIILRGSLNATDCIARMGGDEFAAIVPGCAKEDLEALIQRVRDAFDAYNADPDHVP
THMSVGGACADDMNTTLAQALSEADRNMLAVKHESSPKWRLRIKNWIENRTGKTIQLEDSRYRMSPTHDDS

Sequences:

>Translated_471_residues
MLNKSSIIPEHIQLESHDPVWEWHTTSDRLFMSVGALAQLRMDGKPPRSMKDYLEHCPLESLAPLLESMEKALNGSHGPH
LEVFYPFDSFLVRSQILVLRRDVFGRGTLVTGCNVAMDRQRLAPTAAAAPVPAPQPPPRSLAEAAVPSTARSDASRLMLA
LNAASDGLWDWDPSTNAIYFSPRYLDMLGYTSEEFPPLSTSWTSKVHPDDYDNIVPMQIEFINNPKMGDSFECTYRMQRG
DGTWAWILSRGYVTHRDASGKAIRVVGLHTDVSASQGDRARLEELVRNDALTGLRSRTYYGMTVDKLEQQQMRPVSIIIA
DMDGLKMVNDHVGHTEGSEMLCQAAIILRGSLNATDCIARMGGDEFAAIVPGCAKEDLEALIQRVRDAFDAYNADPDHVP
THMSVGGACADDMNTTLAQALSEADRNMLAVKHESSPKWRLRIKNWIENRTGKTIQLEDSRYRMSPTHDDS
>Mature_471_residues
MLNKSSIIPEHIQLESHDPVWEWHTTSDRLFMSVGALAQLRMDGKPPRSMKDYLEHCPLESLAPLLESMEKALNGSHGPH
LEVFYPFDSFLVRSQILVLRRDVFGRGTLVTGCNVAMDRQRLAPTAAAAPVPAPQPPPRSLAEAAVPSTARSDASRLMLA
LNAASDGLWDWDPSTNAIYFSPRYLDMLGYTSEEFPPLSTSWTSKVHPDDYDNIVPMQIEFINNPKMGDSFECTYRMQRG
DGTWAWILSRGYVTHRDASGKAIRVVGLHTDVSASQGDRARLEELVRNDALTGLRSRTYYGMTVDKLEQQQMRPVSIIIA
DMDGLKMVNDHVGHTEGSEMLCQAAIILRGSLNATDCIARMGGDEFAAIVPGCAKEDLEALIQRVRDAFDAYNADPDHVP
THMSVGGACADDMNTTLAQALSEADRNMLAVKHESSPKWRLRIKNWIENRTGKTIQLEDSRYRMSPTHDDS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=183, Percent_Identity=28.9617486338798, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082007, Length=132, Percent_Identity=30.3030303030303, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787541, Length=209, Percent_Identity=23.9234449760766, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 52457; Mature: 52457

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00133 CARBOXYPEPT_ZN_2 ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKSSIIPEHIQLESHDPVWEWHTTSDRLFMSVGALAQLRMDGKPPRSMKDYLEHCPLE
CCCCCCCCCHHEEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
SLAPLLESMEKALNGSHGPHLEVFYPFDSFLVRSQILVLRRDVFGRGTLVTGCNVAMDRQ
HHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHH
RLAPTAAAAPVPAPQPPPRSLAEAAVPSTARSDASRLMLALNAASDGLWDWDPSTNAIYF
HCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHEEEEEEECCCCCCCCCCCCCCEEEE
SPRYLDMLGYTSEEFPPLSTSWTSKVHPDDYDNIVPMQIEFINNPKMGDSFECTYRMQRG
CCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEEECC
DGTWAWILSRGYVTHRDASGKAIRVVGLHTDVSASQGDRARLEELVRNDALTGLRSRTYY
CCCEEEEEECCCEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEE
GMTVDKLEQQQMRPVSIIIADMDGLKMVNDHVGHTEGSEMLCQAAIILRGSLNATDCIAR
CCCHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
MGGDEFAAIVPGCAKEDLEALIQRVRDAFDAYNADPDHVPTHMSVGGACADDMNTTLAQA
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LSEADRNMLAVKHESSPKWRLRIKNWIENRTGKTIQLEDSRYRMSPTHDDS
HHHHCCCEEEEEECCCCCEEEEEHHHHCCCCCCEEEEECCCEECCCCCCCC
>Mature Secondary Structure
MLNKSSIIPEHIQLESHDPVWEWHTTSDRLFMSVGALAQLRMDGKPPRSMKDYLEHCPLE
CCCCCCCCCHHEEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
SLAPLLESMEKALNGSHGPHLEVFYPFDSFLVRSQILVLRRDVFGRGTLVTGCNVAMDRQ
HHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHH
RLAPTAAAAPVPAPQPPPRSLAEAAVPSTARSDASRLMLALNAASDGLWDWDPSTNAIYF
HCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHEEEEEEECCCCCCCCCCCCCCEEEE
SPRYLDMLGYTSEEFPPLSTSWTSKVHPDDYDNIVPMQIEFINNPKMGDSFECTYRMQRG
CCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEEECC
DGTWAWILSRGYVTHRDASGKAIRVVGLHTDVSASQGDRARLEELVRNDALTGLRSRTYY
CCCEEEEEECCCEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEE
GMTVDKLEQQQMRPVSIIIADMDGLKMVNDHVGHTEGSEMLCQAAIILRGSLNATDCIAR
CCCHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
MGGDEFAAIVPGCAKEDLEALIQRVRDAFDAYNADPDHVPTHMSVGGACADDMNTTLAQA
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LSEADRNMLAVKHESSPKWRLRIKNWIENRTGKTIQLEDSRYRMSPTHDDS
HHHHCCCEEEEEECCCCCEEEEEHHHHCCCCCCEEEEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]