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The map label for this gene is ftsZ [H]

Identifier: 220904389

GI number: 220904389

Start: 1312542

End: 1313852

Strand: Direct

Name: ftsZ [H]

Synonym: Ddes_1118

Alternate gene names: 220904389

Gene position: 1312542-1313852 (Clockwise)

Preceding gene: 220904388

Following gene: 220904390

Centisome position: 45.68

GC content: 57.44

Gene sequence:

>1311_bases
ATGTCTCAGTCGATCGTGGACGATATTGACACGTCTTTGTCCAGCAACGCTAAAATCAAGGTTATAGGCGTTGGCGGCGG
CGGCGGTAATGCGGTGCAGAACATGATAGCCTCCGGTCTGCGCGGTGTGCAGTTTGTCTGCGCCAACACAGACGTGCAGG
CCCTGGCCAAGAATGGCGCTTCTGTAAAAGTGCAGATGGGTGAAAAGCTCACCAAGGGCCTTGGCGCGGGCGCAAACCCT
GCTGTCGGTCGTGAAGCCGCGGTGGAAAGCGTCAATGCCATTCGTGAAGCCATCGGCGATGCAGACATGGTTTTTGTTAC
TGCCGGCATGGGCGGCGGTACCGGTACAGGCGCTGCGCCGGTAGTGGCCCAGGCTGCCAAGGAAATGGGCGCGCTCACAG
TGGGCGTGGTCACCAAGCCGTTCAGCTTTGAAGGCGCCAAGCGCAAGCGTGCCGCTGAAGCCGGGCTTGAAGACTTTAAG
CAGCACGTGGACTGCCTTATCACCATTCCCAATGACCGCCTGCTGGCTTTTGCCCCCAAAAAAGCTCCTTTTGCTGAAAT
GCTGCAGAAAGCCAACGACGTGCTTTACTATGCCGTCAAAGGCATTTCGGATGTGATCGTGGGCGACGGTCTTATCAACC
TGGACTTCGCGGACGTGCGCACAACCATGTCTGAGGCGGGGCTGGCTCTTATGGGAACGGGCATCGCCTCTGGCGAAAAT
CGCGCCCGGGAGGCTGCTCAGCGTGCCATCATGAGTCCCCTGCTCGAAGATGTGTCACTGGAAAGCGCCAAAGCTGTGCT
TTACAATATCACCGCTCCTGAAGACATTACGGCTGAAGAAATCGCAGAGATCGGCGACATCATCAGCGATGCCACACCCG
AAGACTCCAACATCATTTTTGGTGTTGTGTTTGATGACAATATCGGCGATGAGATCCGGCTTACCGTCATTGCTACCGGT
ATTGAGGCTCCTCAGGTCATTCAGAGCCAACAACCGCAGGCTGCCACTGTGACCAACTTCCGCAAGCCTGGTCCTGACGC
CGTCATGGCCGAACCGCGCCGCATGGGCCGTCTGGCTCAGCAGCCCGCTGAAGAGCACGATATGGGTGAAGGGCGCCTGC
CGCGCACGTCGCGCCGTTCTGAAGTAGAACGCTGGTATGACGAAAACAGCAACCGCCCGCCTTATCTGCTCAAGCGTGAA
GTCGTCAACCAGGGCGCTCGCCGTCGTGCACATAACCCCGGCCAGGAAGACTTTACGTACGATGAGGATGATTTCGAAAT
TCCTACCTTTATCCGTACGCAGGCCGACTAG

Upstream 100 bases:

>100_bases
ATGGCGTGCTGGCTCGCATGAAGAAGTGGTTTGCTGATATTTCTTAAACAAACGACCTCAAACGGGCATTTGAGGACAGG
GTAAAACAGGAGAGGAACCT

Downstream 100 bases:

>100_bases
GCAGTCGACCTGTCCGATATAAGATTTTCAGGGCTTGCCTCTTCGGCCCTGAAATGCCCGCCGGGAGGCCCATGGGGGGC
CTCCCAGTGCGGGGCGTTAC

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSQSIVDDIDTSLSSNAKIKVIGVGGGGGNAVQNMIASGLRGVQFVCANTDVQALAKNGASVKVQMGEKLTKGLGAGANP
AVGREAAVESVNAIREAIGDADMVFVTAGMGGGTGTGAAPVVAQAAKEMGALTVGVVTKPFSFEGAKRKRAAEAGLEDFK
QHVDCLITIPNDRLLAFAPKKAPFAEMLQKANDVLYYAVKGISDVIVGDGLINLDFADVRTTMSEAGLALMGTGIASGEN
RAREAAQRAIMSPLLEDVSLESAKAVLYNITAPEDITAEEIAEIGDIISDATPEDSNIIFGVVFDDNIGDEIRLTVIATG
IEAPQVIQSQQPQAATVTNFRKPGPDAVMAEPRRMGRLAQQPAEEHDMGEGRLPRTSRRSEVERWYDENSNRPPYLLKRE
VVNQGARRRAHNPGQEDFTYDEDDFEIPTFIRTQAD

Sequences:

>Translated_436_residues
MSQSIVDDIDTSLSSNAKIKVIGVGGGGGNAVQNMIASGLRGVQFVCANTDVQALAKNGASVKVQMGEKLTKGLGAGANP
AVGREAAVESVNAIREAIGDADMVFVTAGMGGGTGTGAAPVVAQAAKEMGALTVGVVTKPFSFEGAKRKRAAEAGLEDFK
QHVDCLITIPNDRLLAFAPKKAPFAEMLQKANDVLYYAVKGISDVIVGDGLINLDFADVRTTMSEAGLALMGTGIASGEN
RAREAAQRAIMSPLLEDVSLESAKAVLYNITAPEDITAEEIAEIGDIISDATPEDSNIIFGVVFDDNIGDEIRLTVIATG
IEAPQVIQSQQPQAATVTNFRKPGPDAVMAEPRRMGRLAQQPAEEHDMGEGRLPRTSRRSEVERWYDENSNRPPYLLKRE
VVNQGARRRAHNPGQEDFTYDEDDFEIPTFIRTQAD
>Mature_435_residues
SQSIVDDIDTSLSSNAKIKVIGVGGGGGNAVQNMIASGLRGVQFVCANTDVQALAKNGASVKVQMGEKLTKGLGAGANPA
VGREAAVESVNAIREAIGDADMVFVTAGMGGGTGTGAAPVVAQAAKEMGALTVGVVTKPFSFEGAKRKRAAEAGLEDFKQ
HVDCLITIPNDRLLAFAPKKAPFAEMLQKANDVLYYAVKGISDVIVGDGLINLDFADVRTTMSEAGLALMGTGIASGENR
AREAAQRAIMSPLLEDVSLESAKAVLYNITAPEDITAEEIAEIGDIISDATPEDSNIIFGVVFDDNIGDEIRLTVIATGI
EAPQVIQSQQPQAATVTNFRKPGPDAVMAEPRRMGRLAQQPAEEHDMGEGRLPRTSRRSEVERWYDENSNRPPYLLKREV
VNQGARRRAHNPGQEDFTYDEDDFEIPTFIRTQAD

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=407, Percent_Identity=44.4717444717445, Blast_Score=286, Evalue=1e-78,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 46346; Mature: 46215

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSIVDDIDTSLSSNAKIKVIGVGGGGGNAVQNMIASGLRGVQFVCANTDVQALAKNGA
CCCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCC
SVKVQMGEKLTKGLGAGANPAVGREAAVESVNAIREAIGDADMVFVTAGMGGGTGTGAAP
EEEEECHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHH
VVAQAAKEMGALTVGVVTKPFSFEGAKRKRAAEAGLEDFKQHVDCLITIPNDRLLAFAPK
HHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCC
KAPFAEMLQKANDVLYYAVKGISDVIVGDGLINLDFADVRTTMSEAGLALMGTGIASGEN
CCCHHHHHHHHCCEEEEEHHCCHHHEECCCEEECCHHHHHHHHHHCCEEEEECCCCCCHH
RAREAAQRAIMSPLLEDVSLESAKAVLYNITAPEDITAEEIAEIGDIISDATPEDSNIIF
HHHHHHHHHHHHHHHHHHCHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
GVVFDDNIGDEIRLTVIATGIEAPQVIQSQQPQAATVTNFRKPGPDAVMAEPRRMGRLAQ
EEEECCCCCCCEEEEEEEECCCCHHHHHCCCCCHHHHHCCCCCCCCCHHCCHHHHHHHHH
QPAEEHDMGEGRLPRTSRRSEVERWYDENSNRPPYLLKREVVNQGARRRAHNPGQEDFTY
CCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DEDDFEIPTFIRTQAD
CCCCCCCCCEEECCCC
>Mature Secondary Structure 
SQSIVDDIDTSLSSNAKIKVIGVGGGGGNAVQNMIASGLRGVQFVCANTDVQALAKNGA
CCHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCC
SVKVQMGEKLTKGLGAGANPAVGREAAVESVNAIREAIGDADMVFVTAGMGGGTGTGAAP
EEEEECHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHH
VVAQAAKEMGALTVGVVTKPFSFEGAKRKRAAEAGLEDFKQHVDCLITIPNDRLLAFAPK
HHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCC
KAPFAEMLQKANDVLYYAVKGISDVIVGDGLINLDFADVRTTMSEAGLALMGTGIASGEN
CCCHHHHHHHHCCEEEEEHHCCHHHEECCCEEECCHHHHHHHHHHCCEEEEECCCCCCHH
RAREAAQRAIMSPLLEDVSLESAKAVLYNITAPEDITAEEIAEIGDIISDATPEDSNIIF
HHHHHHHHHHHHHHHHHHCHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
GVVFDDNIGDEIRLTVIATGIEAPQVIQSQQPQAATVTNFRKPGPDAVMAEPRRMGRLAQ
EEEECCCCCCCEEEEEEEECCCCHHHHHCCCCCHHHHHCCCCCCCCCHHCCHHHHHHHHH
QPAEEHDMGEGRLPRTSRRSEVERWYDENSNRPPYLLKREVVNQGARRRAHNPGQEDFTY
CCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
DEDDFEIPTFIRTQAD
CCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]