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The map label for this gene is murB [H]

Identifier: 220904386

GI number: 220904386

Start: 1309439

End: 1310329

Strand: Direct

Name: murB [H]

Synonym: Ddes_1115

Alternate gene names: 220904386

Gene position: 1309439-1310329 (Clockwise)

Preceding gene: 220904385

Following gene: 220904387

Centisome position: 45.57

GC content: 54.1

Gene sequence:

>891_bases
ATGCGTGAAATCGCTTCGCCGCAACTCGCCCAGCGTACAACGCTGCACCTTGGCGGGACAGCAATTGCAGAGCTGATTCT
TGAAGGCCCCGAGGATATAGTTCCATTATCGCGCCGTTTGCGCGCTTTGGGAGGAACCCCGGTCGTTTTGGGGGCCGGAA
GCAATATTCTGGCCCAGGATGGCGACCTGCCCCTGGTTCTGATACGGCCGCTCTTTATGCAGGGACCAGAGGTGATTGGT
GAAAAAGAGGGCAGGGTGCTTGTGCGCGCCGGAGCGGGAATGCCCCTGCCGAGGCTCTTGCGTTTTTGCGCGGAGCAGGG
CTTGGCAGGGCTTGAAGGGCTTGTGGGCATACCGGGTACCGTTGGTGGGGCCGTAGCTATGAATGCGGGCTCATTTGGTG
TTGAAGTATGCGAAAAAATTGAAAATTTACAAATAGTTGATGCCGATGGAGTACGCGCTGTTGCATCCTGCGCGCTACAG
TATGCCTACCGCAGCCTGTGTATTGATGAGAAAAAGAATGATTTTATCGTCTTGGAAGCCACATTTGGCTTGACCAGAGC
AGCGAGGGATGGCATCACTAATCGCATGCGTCACAACTTTTTTGAGAAAAAGTCTAAACAACCTGTGACGGCCTGGAGCG
CTGGCTGCGTATTCAAAAATCCCTCTGCGGAACTGCCTGCCGGCAAACTTCTTGATCAGGCGGGATTCAAAGGAAAAAAA
ATGGGCGGCATGGCCTTTTCAACCCTGCACGCCAACTTCATGATTAATGAGGGCAGAGGCAGCGCAAAAGCGGCCCTGGC
CTTGTTGCAAGAGGCAAGAGAAACTGTGCGGGAACGGTTCGGTGTCGTGCTTGAGCCCGAAGTCAGGATTATTCCATGCC
TCTTTCCTTGA

Upstream 100 bases:

>100_bases
CGGGCATTGCCGGATATTCTGCAGGAAGGGGATGTGTTGCTGACCCTGGGGGCGGGCAACATCACCCGTTTGGGGCCGAC
ATGGCTGGAAGGGCTTGATC

Downstream 100 bases:

>100_bases
AAAAAAGCGCCCGCAGGTCCCGCAACGCGTATACGCGCGCCACTGTGACGGGCAAAGGCAAAAAAAACGCAAAGTTTCGT
ATGCCAGCCTTTATGGCTGT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MREIASPQLAQRTTLHLGGTAIAELILEGPEDIVPLSRRLRALGGTPVVLGAGSNILAQDGDLPLVLIRPLFMQGPEVIG
EKEGRVLVRAGAGMPLPRLLRFCAEQGLAGLEGLVGIPGTVGGAVAMNAGSFGVEVCEKIENLQIVDADGVRAVASCALQ
YAYRSLCIDEKKNDFIVLEATFGLTRAARDGITNRMRHNFFEKKSKQPVTAWSAGCVFKNPSAELPAGKLLDQAGFKGKK
MGGMAFSTLHANFMINEGRGSAKAALALLQEARETVRERFGVVLEPEVRIIPCLFP

Sequences:

>Translated_296_residues
MREIASPQLAQRTTLHLGGTAIAELILEGPEDIVPLSRRLRALGGTPVVLGAGSNILAQDGDLPLVLIRPLFMQGPEVIG
EKEGRVLVRAGAGMPLPRLLRFCAEQGLAGLEGLVGIPGTVGGAVAMNAGSFGVEVCEKIENLQIVDADGVRAVASCALQ
YAYRSLCIDEKKNDFIVLEATFGLTRAARDGITNRMRHNFFEKKSKQPVTAWSAGCVFKNPSAELPAGKLLDQAGFKGKK
MGGMAFSTLHANFMINEGRGSAKAALALLQEARETVRERFGVVLEPEVRIIPCLFP
>Mature_296_residues
MREIASPQLAQRTTLHLGGTAIAELILEGPEDIVPLSRRLRALGGTPVVLGAGSNILAQDGDLPLVLIRPLFMQGPEVIG
EKEGRVLVRAGAGMPLPRLLRFCAEQGLAGLEGLVGIPGTVGGAVAMNAGSFGVEVCEKIENLQIVDADGVRAVASCALQ
YAYRSLCIDEKKNDFIVLEATFGLTRAARDGITNRMRHNFFEKKSKQPVTAWSAGCVFKNPSAELPAGKLLDQAGFKGKK
MGGMAFSTLHANFMINEGRGSAKAALALLQEARETVRERFGVVLEPEVRIIPCLFP

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=294, Percent_Identity=29.9319727891156, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 31587; Mature: 31587

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIASPQLAQRTTLHLGGTAIAELILEGPEDIVPLSRRLRALGGTPVVLGAGSNILAQD
CCCCCCCHHHHHHEEEECHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECC
GDLPLVLIRPLFMQGPEVIGEKEGRVLVRAGAGMPLPRLLRFCAEQGLAGLEGLVGIPGT
CCCCCCEECHHHHCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
VGGAVAMNAGSFGVEVCEKIENLQIVDADGVRAVASCALQYAYRSLCIDEKKNDFIVLEA
CCCCEEECCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TFGLTRAARDGITNRMRHNFFEKKSKQPVTAWSAGCVFKNPSAELPAGKLLDQAGFKGKK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEECCCCCCCCHHHHHHHCCCCCCC
MGGMAFSTLHANFMINEGRGSAKAALALLQEARETVRERFGVVLEPEVRIIPCLFP
CCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEECCC
>Mature Secondary Structure
MREIASPQLAQRTTLHLGGTAIAELILEGPEDIVPLSRRLRALGGTPVVLGAGSNILAQD
CCCCCCCHHHHHHEEEECHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECC
GDLPLVLIRPLFMQGPEVIGEKEGRVLVRAGAGMPLPRLLRFCAEQGLAGLEGLVGIPGT
CCCCCCEECHHHHCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
VGGAVAMNAGSFGVEVCEKIENLQIVDADGVRAVASCALQYAYRSLCIDEKKNDFIVLEA
CCCCEEECCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TFGLTRAARDGITNRMRHNFFEKKSKQPVTAWSAGCVFKNPSAELPAGKLLDQAGFKGKK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEECCCCCCCCHHHHHHHCCCCCCC
MGGMAFSTLHANFMINEGRGSAKAALALLQEARETVRERFGVVLEPEVRIIPCLFP
CCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA