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The map label for this gene is engD [H]

Identifier: 220904219

GI number: 220904219

Start: 1103026

End: 1104129

Strand: Reverse

Name: engD [H]

Synonym: Ddes_0946

Alternate gene names: 220904219

Gene position: 1104129-1103026 (Counterclockwise)

Preceding gene: 220904220

Following gene: 220904210

Centisome position: 38.43

GC content: 57.07

Gene sequence:

>1104_bases
ATGGCCCTCAGCATAGGTATCGTCGGTCTGCCCAACGTGGGCAAGTCCACTCTTTTCAATGCCCTTACCAAGGCCCAGAA
CGCCCAGGCCGCCAATTACCCCTTCTGCACCATCGAGCCAAACAAGGCTACGGTGGCCGTGCCGGACACGCGCCTGCAGG
ATCTGACAAACAAGGCAAAACCACAAAAAACCATCAACGCCAGTGTGGATTTTATCGACATTGCCGGTCTTGTGCGGGGA
GCCAGTAAGGGTGAAGGCCTTGGTAACCAGTTTTTGGGCAACATCCGCGAATGCGCGGCCATAGTTCATGTGGTACGCTG
CTTTGAGGATGAAAACATCACCCACGTTGACGGCGGCGTTGATCCCCTGCGTGATGTGGACACCATTGAGACGGAGCTTT
TGCTGGCCGACCTGCAAAGTGTTGAAAAACGCCTTGAACGTCTGCAAAAGATGTCCAAGGGCAACAAGGACGCCAAGGCA
GCTGCCGAAGTGATGCAGACCCTGCAGACGCACCTGAATGACGGCAAGGCCGCCCGCGAATTTGCCCTGCCGGAAGGCAA
CGAGGCCTTTCTGGCTTCGTGGCGTGAACTGGGTCTTCTGACAGCCAAGCCCGTTATCTACTGCGCTAACGTGGATGAAA
ACGCCGTGGCCGAGGGCAACGCCTTTGTGGAAACCCTCAAAAACTTTGCTGCCGGGCGCAACGCAGGCTTTGCCTGTATT
TGCGCCAAGCTCGAAGAAGAACTGCAGGGGTTGTCCGATGCCGAACAGGCCGAAATGCTTTCGTCGTACGGCATTACCGA
AAGCGGCCTTGTGCGCATCATCCGCACCGGCTACGAAACACTGGGCCTTTGCAGCTACTTTACGGTCGGCCCCCAGGAAG
TGCGGGCCTGGACCATTCACAAGGGCTGGAAGGCCCCCCAGGCTGCCGGGGTCATTCATACGGACTTTGAACGCGGCTTC
ATCCGTGCCGAGGTCATCTCTTACCAGGACTACATGAGCCACGAAAACGAGGCCGCCTGCCGCGCCAGCGGCGTGCTGCG
TGTGGAAGGCAAAGAATATGTGGTCAAGGATGGGGATGTCATGCATTTTCTTTTCAACGTGTAG

Upstream 100 bases:

>100_bases
CAGCTCAGTATGGACACCGACCCGGCCCCCTCCGGAGCAGCCGCGCGTGTGCGGCCCGGACGCCCGCCGGGTCTTGACTG
GTGACAATTCAGGAGAAAGC

Downstream 100 bases:

>100_bases
CGCAGCTGCTTGTCTGAAGTGTCCTGACTGTCCGCACATGGGGCCTGCGCTGCGGGAGTTTGTGTACCCCAGCCACCAGG
CATGGCAGCAGGGTAGAAAT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MALSIGIVGLPNVGKSTLFNALTKAQNAQAANYPFCTIEPNKATVAVPDTRLQDLTNKAKPQKTINASVDFIDIAGLVRG
ASKGEGLGNQFLGNIRECAAIVHVVRCFEDENITHVDGGVDPLRDVDTIETELLLADLQSVEKRLERLQKMSKGNKDAKA
AAEVMQTLQTHLNDGKAAREFALPEGNEAFLASWRELGLLTAKPVIYCANVDENAVAEGNAFVETLKNFAAGRNAGFACI
CAKLEEELQGLSDAEQAEMLSSYGITESGLVRIIRTGYETLGLCSYFTVGPQEVRAWTIHKGWKAPQAAGVIHTDFERGF
IRAEVISYQDYMSHENEAACRASGVLRVEGKEYVVKDGDVMHFLFNV

Sequences:

>Translated_367_residues
MALSIGIVGLPNVGKSTLFNALTKAQNAQAANYPFCTIEPNKATVAVPDTRLQDLTNKAKPQKTINASVDFIDIAGLVRG
ASKGEGLGNQFLGNIRECAAIVHVVRCFEDENITHVDGGVDPLRDVDTIETELLLADLQSVEKRLERLQKMSKGNKDAKA
AAEVMQTLQTHLNDGKAAREFALPEGNEAFLASWRELGLLTAKPVIYCANVDENAVAEGNAFVETLKNFAAGRNAGFACI
CAKLEEELQGLSDAEQAEMLSSYGITESGLVRIIRTGYETLGLCSYFTVGPQEVRAWTIHKGWKAPQAAGVIHTDFERGF
IRAEVISYQDYMSHENEAACRASGVLRVEGKEYVVKDGDVMHFLFNV
>Mature_366_residues
ALSIGIVGLPNVGKSTLFNALTKAQNAQAANYPFCTIEPNKATVAVPDTRLQDLTNKAKPQKTINASVDFIDIAGLVRGA
SKGEGLGNQFLGNIRECAAIVHVVRCFEDENITHVDGGVDPLRDVDTIETELLLADLQSVEKRLERLQKMSKGNKDAKAA
AEVMQTLQTHLNDGKAAREFALPEGNEAFLASWRELGLLTAKPVIYCANVDENAVAEGNAFVETLKNFAAGRNAGFACIC
AKLEEELQGLSDAEQAEMLSSYGITESGLVRIIRTGYETLGLCSYFTVGPQEVRAWTIHKGWKAPQAAGVIHTDFERGFI
RAEVISYQDYMSHENEAACRASGVLRVEGKEYVVKDGDVMHFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=43.7837837837838, Blast_Score=305, Evalue=4e-83,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=37.4449339207048, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1787454, Length=368, Percent_Identity=51.9021739130435, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1789574, Length=129, Percent_Identity=31.0077519379845, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=369, Percent_Identity=42.2764227642276, Blast_Score=291, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6319499, Length=371, Percent_Identity=40.4312668463612, Blast_Score=252, Evalue=6e-68,
Organism=Saccharomyces cerevisiae, GI6321773, Length=380, Percent_Identity=37.3684210526316, Blast_Score=236, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6321649, Length=183, Percent_Identity=35.5191256830601, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=42.5474254742547, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=42.5474254742547, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=42.5474254742547, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=39.7553516819572, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI20129375, Length=152, Percent_Identity=30.2631578947368, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39929; Mature: 39797

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSIGIVGLPNVGKSTLFNALTKAQNAQAANYPFCTIEPNKATVAVPDTRLQDLTNKAK
CEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHCC
PQKTINASVDFIDIAGLVRGASKGEGLGNQFLGNIRECAAIVHVVRCFEDENITHVDGGV
CCHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
DPLRDVDTIETELLLADLQSVEKRLERLQKMSKGNKDAKAAAEVMQTLQTHLNDGKAARE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHH
FALPEGNEAFLASWRELGLLTAKPVIYCANVDENAVAEGNAFVETLKNFAAGRNAGFACI
HCCCCCCHHHHHHHHHCCCEECCCEEEEECCCCCCHHCCHHHHHHHHHHHCCCCCCHHHH
CAKLEEELQGLSDAEQAEMLSSYGITESGLVRIIRTGYETLGLCSYFTVGPQEVRAWTIH
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHCCCHHHHEEEEEE
KGWKAPQAAGVIHTDFERGFIRAEVISYQDYMSHENEAACRASGVLRVEGKEYVVKDGDV
CCCCCCCCCCCEEECHHCCHHHHHHHHHHHHHCCCCCHHHHHCCEEEECCCEEEEECCCE
MHFLFNV
EEHEECC
>Mature Secondary Structure 
ALSIGIVGLPNVGKSTLFNALTKAQNAQAANYPFCTIEPNKATVAVPDTRLQDLTNKAK
EEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHCC
PQKTINASVDFIDIAGLVRGASKGEGLGNQFLGNIRECAAIVHVVRCFEDENITHVDGGV
CCHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
DPLRDVDTIETELLLADLQSVEKRLERLQKMSKGNKDAKAAAEVMQTLQTHLNDGKAARE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHH
FALPEGNEAFLASWRELGLLTAKPVIYCANVDENAVAEGNAFVETLKNFAAGRNAGFACI
HCCCCCCHHHHHHHHHCCCEECCCEEEEECCCCCCHHCCHHHHHHHHHHHCCCCCCHHHH
CAKLEEELQGLSDAEQAEMLSSYGITESGLVRIIRTGYETLGLCSYFTVGPQEVRAWTIH
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHCCCHHHHEEEEEE
KGWKAPQAAGVIHTDFERGFIRAEVISYQDYMSHENEAACRASGVLRVEGKEYVVKDGDV
CCCCCCCCCCCEEECHHCCHHHHHHHHHHHHHCCCCCHHHHHCCEEEECCCEEEEECCCE
MHFLFNV
EEHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]