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The map label for this gene is cobT [H]

Identifier: 220904164

GI number: 220904164

Start: 1038932

End: 1040050

Strand: Direct

Name: cobT [H]

Synonym: Ddes_0891

Alternate gene names: 220904164

Gene position: 1038932-1040050 (Clockwise)

Preceding gene: 220904158

Following gene: 220904165

Centisome position: 36.16

GC content: 63.63

Gene sequence:

>1119_bases
ATGAACGACAGCACTTTTTCATCTTCTTGTCCGTCCCCCTGGCTGGAACGTTTTTTCCCCGGCTTGCGTATTGAACCACT
GCGGCAGCAGGATATGGTTGCGGCCCAGGCCCATCTGGACAATCTTACCAAGCCCCGGGGCAGTCTCGGCAGGCTCGAGG
ACCTGGCCCGCAGGATTTACGCCATGCGCCGGGGGCAGACGCCTTTGAGCGTCAGCCCGGCTCTCATGCTGACAGTGGCT
GGCGACCACGGCGTGGCGGCGCAAGGTGTTTCACCTTTTCCACAGGCTGTGACGCGCCAGATGGTGCAGAATTTTTTTGA
TGGCGGCGCGGCCATCAATGTGCTGTGCCGCAGCACGGGTATGGATATGCTTGTTGTGGACGCCGGGTGCGCGGGTGGTC
CCTTTGCGGCGCACCCCATCCTGCTTGACCGCCGCCTCGGCAACGGCACGGCAGACTTGAGCCTTGGTCCGGCCATGAGC
ATCGATGTCTGCCTGGCGGCCCTGCGCACGGGCATCGAACTGGCCCATGACGCCGCCGACAAGGGCTATCAATGTCTTGG
CGTGGGTGAAATGGGCATTGCCAACTCCACTTCCGGCACAGCACTTTACTGCGCCCTGCTGGGGCTTGATCCCGAAGTCA
TGGCCGGACCGGGAGCCGGGTCGGATGCGGCCATGGTGCGCCACAAGGCCGAGGTTGTGCGCCGCGCTCTTGCCGTTAAT
GCAGGGCATCTGAGCGCTGGTGACCCGGTGGCTGTTCTGGCGGCCCTTGGTGGATTTGAAATTGCCGTCATGAGTGGCGT
CATGCTGGGCGCCGCCTCGCGCCGCCTGCCGGTGCTGGTGGACGGCTTTATCTGCAGTGCCGCATATGTGGCAGCTTTGC
GCATATGCCCGACCCTGGGCGATTATGCGGTGCTGGCCCACGCTTCGGCCGAACAGGGGCATGGACGCGCTTTGGCCCGG
CTTGAAACGGCCGCCACCGACCACCGTCCTCTCCTGCATCTGGACATGCGGCTGGGCGAAGGCACAGGGGGGGCCACTGC
CTACGCGCTGCTGCGCTGCGCTGCGGACATATACAATGATATGGCTACATTCGGTGCAGCCGGAGTAGATGCGTGCTGA

Upstream 100 bases:

>100_bases
ACATAACCATCGTGAACTGTTCGTAAAGGGCCGCGAAGCAGATTGCCGAATAAAAGGCCCGGCCCTTGCGCAGGATTGCC
GGAAAGGCTAGAGAAAAAAC

Downstream 100 bases:

>100_bases
GCGGCGAGCAGGGCATGCGGGCTGACGGCGCGGCACCTGACACGAGGTTGGACGCGGTTGGACCGGACAGGGCCAATGAG
CCTATGGATGGTATGTTTCC

Product: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNDSTFSSSCPSPWLERFFPGLRIEPLRQQDMVAAQAHLDNLTKPRGSLGRLEDLARRIYAMRRGQTPLSVSPALMLTVA
GDHGVAAQGVSPFPQAVTRQMVQNFFDGGAAINVLCRSTGMDMLVVDAGCAGGPFAAHPILLDRRLGNGTADLSLGPAMS
IDVCLAALRTGIELAHDAADKGYQCLGVGEMGIANSTSGTALYCALLGLDPEVMAGPGAGSDAAMVRHKAEVVRRALAVN
AGHLSAGDPVAVLAALGGFEIAVMSGVMLGAASRRLPVLVDGFICSAAYVAALRICPTLGDYAVLAHASAEQGHGRALAR
LETAATDHRPLLHLDMRLGEGTGGATAYALLRCAADIYNDMATFGAAGVDAC

Sequences:

>Translated_372_residues
MNDSTFSSSCPSPWLERFFPGLRIEPLRQQDMVAAQAHLDNLTKPRGSLGRLEDLARRIYAMRRGQTPLSVSPALMLTVA
GDHGVAAQGVSPFPQAVTRQMVQNFFDGGAAINVLCRSTGMDMLVVDAGCAGGPFAAHPILLDRRLGNGTADLSLGPAMS
IDVCLAALRTGIELAHDAADKGYQCLGVGEMGIANSTSGTALYCALLGLDPEVMAGPGAGSDAAMVRHKAEVVRRALAVN
AGHLSAGDPVAVLAALGGFEIAVMSGVMLGAASRRLPVLVDGFICSAAYVAALRICPTLGDYAVLAHASAEQGHGRALAR
LETAATDHRPLLHLDMRLGEGTGGATAYALLRCAADIYNDMATFGAAGVDAC
>Mature_372_residues
MNDSTFSSSCPSPWLERFFPGLRIEPLRQQDMVAAQAHLDNLTKPRGSLGRLEDLARRIYAMRRGQTPLSVSPALMLTVA
GDHGVAAQGVSPFPQAVTRQMVQNFFDGGAAINVLCRSTGMDMLVVDAGCAGGPFAAHPILLDRRLGNGTADLSLGPAMS
IDVCLAALRTGIELAHDAADKGYQCLGVGEMGIANSTSGTALYCALLGLDPEVMAGPGAGSDAAMVRHKAEVVRRALAVN
AGHLSAGDPVAVLAALGGFEIAVMSGVMLGAASRRLPVLVDGFICSAAYVAALRICPTLGDYAVLAHASAEQGHGRALAR
LETAATDHRPLLHLDMRLGEGTGGATAYALLRCAADIYNDMATFGAAGVDAC

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=340, Percent_Identity=37.0588235294118, Blast_Score=191, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 38452; Mature: 38452

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSTFSSSCPSPWLERFFPGLRIEPLRQQDMVAAQAHLDNLTKPRGSLGRLEDLARRIY
CCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AMRRGQTPLSVSPALMLTVAGDHGVAAQGVSPFPQAVTRQMVQNFFDGGAAINVLCRSTG
HHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC
MDMLVVDAGCAGGPFAAHPILLDRRLGNGTADLSLGPAMSIDVCLAALRTGIELAHDAAD
CCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
KGYQCLGVGEMGIANSTSGTALYCALLGLDPEVMAGPGAGSDAAMVRHKAEVVRRALAVN
CCCEEEECCCCCCCCCCCCCEEEEEECCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHC
AGHLSAGDPVAVLAALGGFEIAVMSGVMLGAASRRLPVLVDGFICSAAYVAALRICPTLG
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCC
DYAVLAHASAEQGHGRALARLETAATDHRPLLHLDMRLGEGTGGATAYALLRCAADIYND
CHHEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
MATFGAAGVDAC
HHHHCCCCCCCC
>Mature Secondary Structure
MNDSTFSSSCPSPWLERFFPGLRIEPLRQQDMVAAQAHLDNLTKPRGSLGRLEDLARRIY
CCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AMRRGQTPLSVSPALMLTVAGDHGVAAQGVSPFPQAVTRQMVQNFFDGGAAINVLCRSTG
HHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC
MDMLVVDAGCAGGPFAAHPILLDRRLGNGTADLSLGPAMSIDVCLAALRTGIELAHDAAD
CCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
KGYQCLGVGEMGIANSTSGTALYCALLGLDPEVMAGPGAGSDAAMVRHKAEVVRRALAVN
CCCEEEECCCCCCCCCCCCCEEEEEECCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHC
AGHLSAGDPVAVLAALGGFEIAVMSGVMLGAASRRLPVLVDGFICSAAYVAALRICPTLG
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCC
DYAVLAHASAEQGHGRALARLETAATDHRPLLHLDMRLGEGTGGATAYALLRCAADIYND
CHHEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
MATFGAAGVDAC
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA