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The map label for this gene is menA [H]

Identifier: 220904147

GI number: 220904147

Start: 1023404

End: 1024381

Strand: Reverse

Name: menA [H]

Synonym: Ddes_0874

Alternate gene names: 220904147

Gene position: 1024381-1023404 (Counterclockwise)

Preceding gene: 220904148

Following gene: 220904143

Centisome position: 35.65

GC content: 62.07

Gene sequence:

>978_bases
ATGAATTACGGCAATCTGCTGCGGGCTGCCTGGCAAGGGCGGCCCGCCGATGCCCCGCGGCTCTCGGCTGCCGGGCATTT
CCAGGCATGGTGGCAGGCCTGCCGCCCGCCTTTTCTCATCACCGCGGCCATACCCGTCACCCTGGCCCTGTCCTTTGCCT
TTCGCCTCCAGGGGCAGATTACTCCCCGCCAATGGCTGATATACGCCCTGCTTCTGCTGGGCTGCTTTCTGGGCCTGACC
ATCGCCAATTTTGCCAATGACCTGTTTGACCATATCCTTGGCGTGGATGGCGGTGACAATATCGGCGGCTCGCGTGTGAT
ACAGAGCGGCTTTATCAGTCCCCGCCAGCTCTCCGTGGCGCTTCTGCTGCTTGCCCCGGCCACCCTGGCTGTAGGCGGCC
TGCTGGCCACGCTGGCGCCAGCCGGCCTGCGGCCCGGCCTGTGGCTTGTAAGTATTTTTGCCGTCGCCTCGGCCATCTTT
TATGTGGCTCCGCCCATACGCTACGGACACAGGGCGCTTGGCGAGCTTTTTGTATGCCTGAACATGGGCGTCATCATGGT
CAGCGCCAGCGCTGCCCTGCTGCTTGAAGGATTTGACCCGCGCAGCCTGGCTCTGTCGCTGCCTGTGGGTCTTATGGTGG
CGGGAGTACTCTATTACCAGAGTCTGCCTGAAATCGAGACAGACCTGGCCGCAGGCAAGCATACACTTGCCAACAGGCTG
GGCAAGGACAAGGCCGCCCTTGTTTTTCGCCTGTGGTGGCCCGCTGTGTGGATTTTGCTGCTCAATCTGTGGGCTGCTGG
CCTGGCCGGATGGCCCGTGGCTCTGACCCTGCTTGGCCTGCCTTTTTATCTGCGGACCTGCCGCCACATAAGTGATGCAG
GAACAGGCGACTGGCTGCACCTGGATTCATTCGGCCACCTTGTGCGCACGTGTTACCTGCTGAGCGGTGCCGCGCTTATT
GCGGGGGTAGCCCTGTAA

Upstream 100 bases:

>100_bases
GCAACTGCGCGGATATCCCTCACGATCCCGCCGAGGGACAGCGCCTGCCCGTGGACGATCCGTCCATTCCCTATTGCTGG
AAAACGGAAAAGGCATAATC

Downstream 100 bases:

>100_bases
TCGGCACGGTAAAAAATCTCCGAACCGGAAAGCATAAATGCCCGGAAAGTCTGTTTTGGCAGAGCTTCCGGGCGTTCATG
CAAATGGGACAGGAATGAAA

Product: UbiA prenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNYGNLLRAAWQGRPADAPRLSAAGHFQAWWQACRPPFLITAAIPVTLALSFAFRLQGQITPRQWLIYALLLLGCFLGLT
IANFANDLFDHILGVDGGDNIGGSRVIQSGFISPRQLSVALLLLAPATLAVGGLLATLAPAGLRPGLWLVSIFAVASAIF
YVAPPIRYGHRALGELFVCLNMGVIMVSASAALLLEGFDPRSLALSLPVGLMVAGVLYYQSLPEIETDLAAGKHTLANRL
GKDKAALVFRLWWPAVWILLLNLWAAGLAGWPVALTLLGLPFYLRTCRHISDAGTGDWLHLDSFGHLVRTCYLLSGAALI
AGVAL

Sequences:

>Translated_325_residues
MNYGNLLRAAWQGRPADAPRLSAAGHFQAWWQACRPPFLITAAIPVTLALSFAFRLQGQITPRQWLIYALLLLGCFLGLT
IANFANDLFDHILGVDGGDNIGGSRVIQSGFISPRQLSVALLLLAPATLAVGGLLATLAPAGLRPGLWLVSIFAVASAIF
YVAPPIRYGHRALGELFVCLNMGVIMVSASAALLLEGFDPRSLALSLPVGLMVAGVLYYQSLPEIETDLAAGKHTLANRL
GKDKAALVFRLWWPAVWILLLNLWAAGLAGWPVALTLLGLPFYLRTCRHISDAGTGDWLHLDSFGHLVRTCYLLSGAALI
AGVAL
>Mature_325_residues
MNYGNLLRAAWQGRPADAPRLSAAGHFQAWWQACRPPFLITAAIPVTLALSFAFRLQGQITPRQWLIYALLLLGCFLGLT
IANFANDLFDHILGVDGGDNIGGSRVIQSGFISPRQLSVALLLLAPATLAVGGLLATLAPAGLRPGLWLVSIFAVASAIF
YVAPPIRYGHRALGELFVCLNMGVIMVSASAALLLEGFDPRSLALSLPVGLMVAGVLYYQSLPEIETDLAAGKHTLANRL
GKDKAALVFRLWWPAVWILLLNLWAAGLAGWPVALTLLGLPFYLRTCRHISDAGTGDWLHLDSFGHLVRTCYLLSGAALI
AGVAL

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

Organism=Escherichia coli, GI1790365, Length=268, Percent_Identity=28.7313432835821, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004657
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 34813; Mature: 34813

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYGNLLRAAWQGRPADAPRLSAAGHFQAWWQACRPPFLITAAIPVTLALSFAFRLQGQI
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCC
TPRQWLIYALLLLGCFLGLTIANFANDLFDHILGVDGGDNIGGSRVIQSGFISPRQLSVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHH
LLLLAPATLAVGGLLATLAPAGLRPGLWLVSIFAVASAIFYVAPPIRYGHRALGELFVCL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NMGVIMVSASAALLLEGFDPRSLALSLPVGLMVAGVLYYQSLPEIETDLAAGKHTLANRL
HCCHHHHHHHHHHHEECCCCHHHEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GKDKAALVFRLWWPAVWILLLNLWAAGLAGWPVALTLLGLPFYLRTCRHISDAGTGDWLH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LDSFGHLVRTCYLLSGAALIAGVAL
EHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYGNLLRAAWQGRPADAPRLSAAGHFQAWWQACRPPFLITAAIPVTLALSFAFRLQGQI
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCC
TPRQWLIYALLLLGCFLGLTIANFANDLFDHILGVDGGDNIGGSRVIQSGFISPRQLSVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHH
LLLLAPATLAVGGLLATLAPAGLRPGLWLVSIFAVASAIFYVAPPIRYGHRALGELFVCL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
NMGVIMVSASAALLLEGFDPRSLALSLPVGLMVAGVLYYQSLPEIETDLAAGKHTLANRL
HCCHHHHHHHHHHHEECCCCHHHEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GKDKAALVFRLWWPAVWILLLNLWAAGLAGWPVALTLLGLPFYLRTCRHISDAGTGDWLH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LDSFGHLVRTCYLLSGAALIAGVAL
EHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]