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The map label for this gene is hflK [H]

Identifier: 220904139

GI number: 220904139

Start: 1015919

End: 1017082

Strand: Direct

Name: hflK [H]

Synonym: Ddes_0866

Alternate gene names: 220904139

Gene position: 1015919-1017082 (Clockwise)

Preceding gene: 220904138

Following gene: 220904140

Centisome position: 35.36

GC content: 58.76

Gene sequence:

>1164_bases
ATGAATTGGGATTGGGACAAGCTACAGGAAAAGAGGCAACGGCAGCAGGGGGCCAATCCTCCCCCCAAGCCGCCCCGCAA
CACTGAGCCTGACAACGATGAAGGGCAGGACCGGCAGCCCCCACGGGCGCGGCGTACTCCTTTTAACGGTCGGGGCAGAG
GGGATGACAATCCCTTGAAAAAACTGTCGCAGATGAACCTTCCCAATGGAAAGGCCTTTTTTCTGATCGGTCTGGCGGTG
GTGGGGCTGTGGCTTCTTTCGGGTATTTACATCATTAATCCCGACGAGCAGGGCGTGGTGCTGCGCTTCGGCAAGTATAA
CCGCACCGAAGGTCCCGGTCCTCATTACGCATGGCCTGCCCCCATAGAAAGCGTGTACAAACCGCAGGTTACCCAGGTGC
TGCGCAGTGAGGTGGGTTTTCGCTCCGTGGGGCAGAGCACCACATTTCAGCAGGGGCAGGTGCGCACGGTCTCTGAAGAA
GCGTCCATGCTCACCGGCGATGAAAATATCGTCAATGTGCAGTTCAGTGTACAGTACAAGATCGGTGATCCGGTACAGTA
TCTGTTTAACGTGAGCGCGCCCACGGCTCTTGTGCGCAATGCCGCCGAGGCCGCCATGCGCGAGGTCATCGGCAATAGCC
AGATCGACTCGGCCATCACTGACGGCAAGCTGAAAATCCAGAGCGAGGCCACACAGCTTCTGCAGACCATTCTGGACCGC
TACGGTGCGGGCATCCAGGTGCTGGCCGTACAGTTGCAGGACGTGCACCCCCCGCAGGAAGTCATTGATGCCTTCAAGGA
CGTTGCCAGCGCCAGAGAAGACAAGAGCCGCATCATCAACGAGGCCGAAGCCTACCGCAACGAACTGCTGCCCAAGGCAC
GAGGCCAGGCGGCGGCCATGCTCAACGAGGCAGAATCGTATCATGCTGTGCGCGTGCGCACAGCCGAGGGTGAAACCTCC
CGTTTTGACGCCCTGAGCGCGGAACACCGCAAGGCCCCCAAGGTCACCGAGCAGCGCCTTTACTATGAAACTATGGAAGA
TATTCTTGCCGGTGCTGATGAAAAAGTGCTTATGGATGCCCCGGCGGCATCCCGTGCCTTGCCTTATCTGAATCTGCCCA
GCCTGGGCGCCCCTGTTGCCCCCAAGGCGTTGGAGAGAAAATAA

Upstream 100 bases:

>100_bases
CCCTATTTTTATCTCTTCACACATATTAAAATCGCAAACATTTTTCAGTCATGATCGGCTGAAATCATGTCGCGAATCAA
AAAAAAGGTAAACCTCCGTC

Downstream 100 bases:

>100_bases
TGCGTACCAATCCTCTGCCGGCTGTCATCGTGCTGCTGCTGATCGTTGTGGTGGGTAGCCAGTGCTTTTTTACTGTCCAT
CAGACGCAAACGGCTCTTGT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNWDWDKLQEKRQRQQGANPPPKPPRNTEPDNDEGQDRQPPRARRTPFNGRGRGDDNPLKKLSQMNLPNGKAFFLIGLAV
VGLWLLSGIYIINPDEQGVVLRFGKYNRTEGPGPHYAWPAPIESVYKPQVTQVLRSEVGFRSVGQSTTFQQGQVRTVSEE
ASMLTGDENIVNVQFSVQYKIGDPVQYLFNVSAPTALVRNAAEAAMREVIGNSQIDSAITDGKLKIQSEATQLLQTILDR
YGAGIQVLAVQLQDVHPPQEVIDAFKDVASAREDKSRIINEAEAYRNELLPKARGQAAAMLNEAESYHAVRVRTAEGETS
RFDALSAEHRKAPKVTEQRLYYETMEDILAGADEKVLMDAPAASRALPYLNLPSLGAPVAPKALERK

Sequences:

>Translated_387_residues
MNWDWDKLQEKRQRQQGANPPPKPPRNTEPDNDEGQDRQPPRARRTPFNGRGRGDDNPLKKLSQMNLPNGKAFFLIGLAV
VGLWLLSGIYIINPDEQGVVLRFGKYNRTEGPGPHYAWPAPIESVYKPQVTQVLRSEVGFRSVGQSTTFQQGQVRTVSEE
ASMLTGDENIVNVQFSVQYKIGDPVQYLFNVSAPTALVRNAAEAAMREVIGNSQIDSAITDGKLKIQSEATQLLQTILDR
YGAGIQVLAVQLQDVHPPQEVIDAFKDVASAREDKSRIINEAEAYRNELLPKARGQAAAMLNEAESYHAVRVRTAEGETS
RFDALSAEHRKAPKVTEQRLYYETMEDILAGADEKVLMDAPAASRALPYLNLPSLGAPVAPKALERK
>Mature_387_residues
MNWDWDKLQEKRQRQQGANPPPKPPRNTEPDNDEGQDRQPPRARRTPFNGRGRGDDNPLKKLSQMNLPNGKAFFLIGLAV
VGLWLLSGIYIINPDEQGVVLRFGKYNRTEGPGPHYAWPAPIESVYKPQVTQVLRSEVGFRSVGQSTTFQQGQVRTVSEE
ASMLTGDENIVNVQFSVQYKIGDPVQYLFNVSAPTALVRNAAEAAMREVIGNSQIDSAITDGKLKIQSEATQLLQTILDR
YGAGIQVLAVQLQDVHPPQEVIDAFKDVASAREDKSRIINEAEAYRNELLPKARGQAAAMLNEAESYHAVRVRTAEGETS
RFDALSAEHRKAPKVTEQRLYYETMEDILAGADEKVLMDAPAASRALPYLNLPSLGAPVAPKALERK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=273, Percent_Identity=38.8278388278388, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 42925; Mature: 42925

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWDWDKLQEKRQRQQGANPPPKPPRNTEPDNDEGQDRQPPRARRTPFNGRGRGDDNPLK
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHH
KLSQMNLPNGKAFFLIGLAVVGLWLLSGIYIINPDEQGVVLRFGKYNRTEGPGPHYAWPA
HHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCC
PIESVYKPQVTQVLRSEVGFRSVGQSTTFQQGQVRTVSEEASMLTGDENIVNVQFSVQYK
CHHHHHCHHHHHHHHHHCCHHHCCCCCCCCCCCEEEHHHHHHHCCCCCCEEEEEEEEEEE
IGDPVQYLFNVSAPTALVRNAAEAAMREVIGNSQIDSAITDGKLKIQSEATQLLQTILDR
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEHHHHHHHHHHHHHH
YGAGIQVLAVQLQDVHPPQEVIDAFKDVASAREDKSRIINEAEAYRNELLPKARGQAAAM
HCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHH
LNEAESYHAVRVRTAEGETSRFDALSAEHRKAPKVTEQRLYYETMEDILAGADEKVLMDA
HHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEC
PAASRALPYLNLPSLGAPVAPKALERK
CCHHHCCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MNWDWDKLQEKRQRQQGANPPPKPPRNTEPDNDEGQDRQPPRARRTPFNGRGRGDDNPLK
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHH
KLSQMNLPNGKAFFLIGLAVVGLWLLSGIYIINPDEQGVVLRFGKYNRTEGPGPHYAWPA
HHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCC
PIESVYKPQVTQVLRSEVGFRSVGQSTTFQQGQVRTVSEEASMLTGDENIVNVQFSVQYK
CHHHHHCHHHHHHHHHHCCHHHCCCCCCCCCCCEEEHHHHHHHCCCCCCEEEEEEEEEEE
IGDPVQYLFNVSAPTALVRNAAEAAMREVIGNSQIDSAITDGKLKIQSEATQLLQTILDR
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEHHHHHHHHHHHHHH
YGAGIQVLAVQLQDVHPPQEVIDAFKDVASAREDKSRIINEAEAYRNELLPKARGQAAAM
HCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHH
LNEAESYHAVRVRTAEGETSRFDALSAEHRKAPKVTEQRLYYETMEDILAGADEKVLMDA
HHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEC
PAASRALPYLNLPSLGAPVAPKALERK
CCHHHCCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]