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The map label for this gene is 220904137

Identifier: 220904137

GI number: 220904137

Start: 1012403

End: 1014061

Strand: Direct

Name: 220904137

Synonym: Ddes_0864

Alternate gene names: NA

Gene position: 1012403-1014061 (Clockwise)

Preceding gene: 220904136

Following gene: 220904138

Centisome position: 35.23

GC content: 58.05

Gene sequence:

>1659_bases
ATGAAAGAACCCTACCTTACCATCACGCCCCTGGGGGGCCTTGGAGAAATCGGCCTCAACTGCCAATTGTGGGAAACCGC
CGGCGGCGTGGTCATGGTGGACTGTGGACTCATGTTCCCCGACGACGCCCATCTGGGCGTGGACGTGGTCATCCCGCATT
TTGGCGCGGTAAGCGCCATCAAAGACAAACTGCTCGGCATCGTGCTCACCCACGGCCATGAAGACCATATCGGGGCCTTG
CCTTGGCTTGTGCCCGAGCTTAAAGGTACACGCATCTACGGTTCGCGTTTTACCCTTGCCCTGGTGGAGCACAAGCTGCG
TGAGCGGGAAATTCTTGACTGGGTGGAACTGTGCCCGGTGGACGCCCGGACGGTTCTGCCCCTGGGCGATCTGACGTTTC
ACTTTTTTCCGGTCTGTCATTCCATTCCCGAAGGCTTCGGACTGGGGGTGGAAACCCCTGTGGGCCGCGTCGTGCACAGC
GGCGACTTCAAGATTGACCCGCATCCCCTGGATGGTACAGGCACGGACCTTGATGTCTTCAGCAACTTTGCAGGCCCGCA
GGGCGCGCGTCTGTTACTTTCAGACTCCACCAACGTCATGCGTGATGGCCGCTCCCTTACGGAAAGGGAAGTGAAGGACT
CGCTGGAAAAGATTTTTTCCAGCGCAGAAGGCCGTATCGTTATTACACTTTTTTCGAGCCATATCCAAAGAATACAGGAA
GTGTTCGACCTTGCACGCGAATACGGGCGCACGGTCGTCATAAGCGGCAAATCACTGGCCAATAATATCGAGATGGCCCG
GGATCTGGGTTTCGCCAAATTGCCGCCCTCTTTTTTCAATGCGCATAACGGTGTTCCCGATCTGCCCGACAACCAGATCG
TTCTGGTGGTCACAGGGGCGCAGGGCGAACCTTTGTCGGCCCTGTCGCGCATGGTGCTCGGCGGTCACAGGCAGCTTGAG
GTGCGCAAGGGCGACACGGTGGTCATGAGTTCGCGCATGATCCCGGGCAATGCCAAGGCCGTAGCCAAGCTTATTAACGA
AATGTACCGCATCGGCGCGGAAGTGCTGTATGAAAGCGTGCATGCCATTCATGCCTCGGGGCATGCCCAGCGCGAAGAAC
TGCGTGAAATGTTCGAGGCCGTGAGGCCGGAACTTTTTGTGCCGGTACACGGCGAATACCAGCATCTGGTCAAGCACGGG
CGTCTGGCCGTGGAGTGTGGGGTAAAAGAAGAAAACGTCGTTCTGCTGGAAGACGGGCAGCCCCTGACCCTGCTGGAAGA
TTCTTTCAGGCTTGAGCAGAAAGTGCCTGTGGAGTGCACCCTTGTGGACGGCAAGGGCGTTGGCGACGTGGGCTATGCCG
TACTGCGCGAGCGCCGGATCCTTGGCGACGAGGGTATGGTTATCGTGGTGCTGGTGGTAGACTCTGAAACGGGCAGTGTA
CTGCACGGGCCGGAAATGATCTCCAAGGGCTTTGTGTTCGAGCAGCATTACAGCCATCTGCTCGAAGATGCCAAGTGCCT
TGTGCTGGATGAGATAGAGGCCGCTCGCCCGGGGCAGCTCAATCGCATGCAGGAGGGCATCCGATCTTCGTTGCGGCGTT
TTTTCCGCCGTGTGCTGGAGCGCGACCCCGTGGTTGTACCCATCATCAGCGAAGTTTAA

Upstream 100 bases:

>100_bases
AGCCCTGTCCCAATTGTATGTGGCCATGGGCGAATTTAAACCTGACCTGATGCGGCGCGACCGGTAAACGGCTTCGCGCC
CAAGCACAAGCGATAGAGGA

Downstream 100 bases:

>100_bases
GGGCAGATCAAGGGCTGCCGCAGTTCAATAAGCAATGCGGCATGCCCAGCCCGGCCAGCCCCGGTAAATACGATTATCCC
GCCGTGCCCACGGCTTTTGC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MKEPYLTITPLGGLGEIGLNCQLWETAGGVVMVDCGLMFPDDAHLGVDVVIPHFGAVSAIKDKLLGIVLTHGHEDHIGAL
PWLVPELKGTRIYGSRFTLALVEHKLREREILDWVELCPVDARTVLPLGDLTFHFFPVCHSIPEGFGLGVETPVGRVVHS
GDFKIDPHPLDGTGTDLDVFSNFAGPQGARLLLSDSTNVMRDGRSLTEREVKDSLEKIFSSAEGRIVITLFSSHIQRIQE
VFDLAREYGRTVVISGKSLANNIEMARDLGFAKLPPSFFNAHNGVPDLPDNQIVLVVTGAQGEPLSALSRMVLGGHRQLE
VRKGDTVVMSSRMIPGNAKAVAKLINEMYRIGAEVLYESVHAIHASGHAQREELREMFEAVRPELFVPVHGEYQHLVKHG
RLAVECGVKEENVVLLEDGQPLTLLEDSFRLEQKVPVECTLVDGKGVGDVGYAVLRERRILGDEGMVIVVLVVDSETGSV
LHGPEMISKGFVFEQHYSHLLEDAKCLVLDEIEAARPGQLNRMQEGIRSSLRRFFRRVLERDPVVVPIISEV

Sequences:

>Translated_552_residues
MKEPYLTITPLGGLGEIGLNCQLWETAGGVVMVDCGLMFPDDAHLGVDVVIPHFGAVSAIKDKLLGIVLTHGHEDHIGAL
PWLVPELKGTRIYGSRFTLALVEHKLREREILDWVELCPVDARTVLPLGDLTFHFFPVCHSIPEGFGLGVETPVGRVVHS
GDFKIDPHPLDGTGTDLDVFSNFAGPQGARLLLSDSTNVMRDGRSLTEREVKDSLEKIFSSAEGRIVITLFSSHIQRIQE
VFDLAREYGRTVVISGKSLANNIEMARDLGFAKLPPSFFNAHNGVPDLPDNQIVLVVTGAQGEPLSALSRMVLGGHRQLE
VRKGDTVVMSSRMIPGNAKAVAKLINEMYRIGAEVLYESVHAIHASGHAQREELREMFEAVRPELFVPVHGEYQHLVKHG
RLAVECGVKEENVVLLEDGQPLTLLEDSFRLEQKVPVECTLVDGKGVGDVGYAVLRERRILGDEGMVIVVLVVDSETGSV
LHGPEMISKGFVFEQHYSHLLEDAKCLVLDEIEAARPGQLNRMQEGIRSSLRRFFRRVLERDPVVVPIISEV
>Mature_552_residues
MKEPYLTITPLGGLGEIGLNCQLWETAGGVVMVDCGLMFPDDAHLGVDVVIPHFGAVSAIKDKLLGIVLTHGHEDHIGAL
PWLVPELKGTRIYGSRFTLALVEHKLREREILDWVELCPVDARTVLPLGDLTFHFFPVCHSIPEGFGLGVETPVGRVVHS
GDFKIDPHPLDGTGTDLDVFSNFAGPQGARLLLSDSTNVMRDGRSLTEREVKDSLEKIFSSAEGRIVITLFSSHIQRIQE
VFDLAREYGRTVVISGKSLANNIEMARDLGFAKLPPSFFNAHNGVPDLPDNQIVLVVTGAQGEPLSALSRMVLGGHRQLE
VRKGDTVVMSSRMIPGNAKAVAKLINEMYRIGAEVLYESVHAIHASGHAQREELREMFEAVRPELFVPVHGEYQHLVKHG
RLAVECGVKEENVVLLEDGQPLTLLEDSFRLEQKVPVECTLVDGKGVGDVGYAVLRERRILGDEGMVIVVLVVDSETGSV
LHGPEMISKGFVFEQHYSHLLEDAKCLVLDEIEAARPGQLNRMQEGIRSSLRRFFRRVLERDPVVVPIISEV

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 60849; Mature: 60849

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEPYLTITPLGGLGEIGLNCQLWETAGGVVMVDCGLMFPDDAHLGVDVVIPHFGAVSAI
CCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEECCEECCCCCCCCEEEEECCCCHHHHH
KDKLLGIVLTHGHEDHIGALPWLVPELKGTRIYGSRFTLALVEHKLREREILDWVELCPV
HHHHEEEEEECCCCCCCCCCCHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
DARTVLPLGDLTFHFFPVCHSIPEGFGLGVETPVGRVVHSGDFKIDPHPLDGTGTDLDVF
CCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEECCCCCCCCCCCHHHH
SNFAGPQGARLLLSDSTNVMRDGRSLTEREVKDSLEKIFSSAEGRIVITLFSSHIQRIQE
HCCCCCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHH
VFDLAREYGRTVVISGKSLANNIEMARDLGFAKLPPSFFNAHNGVPDLPDNQIVLVVTGA
HHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECC
QGEPLSALSRMVLGGHRQLEVRKGDTVVMSSRMIPGNAKAVAKLINEMYRIGAEVLYESV
CCCCHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HAIHASGHAQREELREMFEAVRPELFVPVHGEYQHLVKHGRLAVECGVKEENVVLLEDGQ
HHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCEEEEECCCCCCEEEEECCC
PLTLLEDSFRLEQKVPVECTLVDGKGVGDVGYAVLRERRILGDEGMVIVVLVVDSETGSV
CEEEECCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCE
LHGPEMISKGFVFEQHYSHLLEDAKCLVLDEIEAARPGQLNRMQEGIRSSLRRFFRRVLE
EECHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
RDPVVVPIISEV
CCCEEEEECCCC
>Mature Secondary Structure
MKEPYLTITPLGGLGEIGLNCQLWETAGGVVMVDCGLMFPDDAHLGVDVVIPHFGAVSAI
CCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEECCEECCCCCCCCEEEEECCCCHHHHH
KDKLLGIVLTHGHEDHIGALPWLVPELKGTRIYGSRFTLALVEHKLREREILDWVELCPV
HHHHEEEEEECCCCCCCCCCCHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
DARTVLPLGDLTFHFFPVCHSIPEGFGLGVETPVGRVVHSGDFKIDPHPLDGTGTDLDVF
CCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEECCCCCCCCCCCHHHH
SNFAGPQGARLLLSDSTNVMRDGRSLTEREVKDSLEKIFSSAEGRIVITLFSSHIQRIQE
HCCCCCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHH
VFDLAREYGRTVVISGKSLANNIEMARDLGFAKLPPSFFNAHNGVPDLPDNQIVLVVTGA
HHHHHHHHCCEEEEECHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECC
QGEPLSALSRMVLGGHRQLEVRKGDTVVMSSRMIPGNAKAVAKLINEMYRIGAEVLYESV
CCCCHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HAIHASGHAQREELREMFEAVRPELFVPVHGEYQHLVKHGRLAVECGVKEENVVLLEDGQ
HHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCEEEEECCCCCCEEEEECCC
PLTLLEDSFRLEQKVPVECTLVDGKGVGDVGYAVLRERRILGDEGMVIVVLVVDSETGSV
CEEEECCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCE
LHGPEMISKGFVFEQHYSHLLEDAKCLVLDEIEAARPGQLNRMQEGIRSSLRRFFRRVLE
EECHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
RDPVVVPIISEV
CCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA