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The map label for this gene is ubiA [H]

Identifier: 220903926

GI number: 220903926

Start: 791427

End: 792338

Strand: Reverse

Name: ubiA [H]

Synonym: Ddes_0651

Alternate gene names: 220903926

Gene position: 792338-791427 (Counterclockwise)

Preceding gene: 220903927

Following gene: 220903925

Centisome position: 27.57

GC content: 58.22

Gene sequence:

>912_bases
ATGCGTTTCCAAAATCCTCTTGGCCGGATCAGCCCGCATCTGGGGCGTCTGTCCTCCCCTTTCGGCAAATTTTCGGATAT
CTGCCGGATGATCAAGATCGAGCACTCCATATTTGCCCTGCCGTACGCCTGGGCCGGAGCGTTTCTGGCCGCGCGGGGAA
TGCCCCCGGCATGGAGCCTGGTTTTTCTGACCATCGCCATGGTGGCGGCCCGGTCTTTTGCAATGGCGTTCAACCGCCTT
GTGGACCTGCCCTTTGACAGCGACAACCCGCGCACCCAGAACCGCCCCCTTGTTACCGGGGTCATCTCCACCAGGCAGAC
ATGGGCATTTTGCGGGCTTATGGCCGTCATTTTTGTCGTCGCCTGTGCCTGCATGAACCAGGTCTGCCTGTGGCTTTCCG
TTCCTGCGCTTGTTTTTTCGGCCATTTATAGTGTGCTCAAACGCTTTACGCCCCTGTGCCACTTCTGGCTGGGCGCCACG
CTCGGCCTTGCTCCGCTGGCCGGATGGCTTTCCGTCGATCCCGGCAGGCTGGGCATGGCCCCGATACTGCTGTTTTTTGC
CGTTACCTTTTGGGTGGCCGCCTTTGACGTTTACTACGCCTTTCAGGATATGGACTTTGACGCGGCTTTCGGGCTGCATT
CCATACCGGCCACCTTCGGCACGGAAACCGCGCTTGTTCTGGCGGCCTTTTCGCATGCCATGACATCCATATTCCTGCTG
CTGTCAGGCTTTGCTGCCGGCCTGAGCTGGCCCTGGTATGTGGTATGGCTGGGTATTAGCCTTATGCTTTTTGTGGAGCA
CAGGCTCATGCGCCCGCAAGACCTGCGCCACGTAAACACGGCCTTTTTCACTCTTAACGGCATCATTTCTCCCGTGGTGC
TGGCCGGGGTGATTCTTGGCATTTACCTCTAA

Upstream 100 bases:

>100_bases
CCGGAAACGGTGCGTTGCCGGGGCATGTACGGCACGGGCGCGGCGGATTTTGGCAAAAAATATTTTCCGTACGGATCAGG
ATCAGTTGTAAGGAGAAAAA

Downstream 100 bases:

>100_bases
AAAATACAATTGCTCCAGGATGTTTCATGCCTCGTAAAAAACAGTATCAATGGCAGGCCCATGATGACGGCCAGGGACAG
GACTTCGAGCAGCCCAGCCG

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MRFQNPLGRISPHLGRLSSPFGKFSDICRMIKIEHSIFALPYAWAGAFLAARGMPPAWSLVFLTIAMVAARSFAMAFNRL
VDLPFDSDNPRTQNRPLVTGVISTRQTWAFCGLMAVIFVVACACMNQVCLWLSVPALVFSAIYSVLKRFTPLCHFWLGAT
LGLAPLAGWLSVDPGRLGMAPILLFFAVTFWVAAFDVYYAFQDMDFDAAFGLHSIPATFGTETALVLAAFSHAMTSIFLL
LSGFAAGLSWPWYVVWLGISLMLFVEHRLMRPQDLRHVNTAFFTLNGIISPVVLAGVILGIYL

Sequences:

>Translated_303_residues
MRFQNPLGRISPHLGRLSSPFGKFSDICRMIKIEHSIFALPYAWAGAFLAARGMPPAWSLVFLTIAMVAARSFAMAFNRL
VDLPFDSDNPRTQNRPLVTGVISTRQTWAFCGLMAVIFVVACACMNQVCLWLSVPALVFSAIYSVLKRFTPLCHFWLGAT
LGLAPLAGWLSVDPGRLGMAPILLFFAVTFWVAAFDVYYAFQDMDFDAAFGLHSIPATFGTETALVLAAFSHAMTSIFLL
LSGFAAGLSWPWYVVWLGISLMLFVEHRLMRPQDLRHVNTAFFTLNGIISPVVLAGVILGIYL
>Mature_303_residues
MRFQNPLGRISPHLGRLSSPFGKFSDICRMIKIEHSIFALPYAWAGAFLAARGMPPAWSLVFLTIAMVAARSFAMAFNRL
VDLPFDSDNPRTQNRPLVTGVISTRQTWAFCGLMAVIFVVACACMNQVCLWLSVPALVFSAIYSVLKRFTPLCHFWLGAT
LGLAPLAGWLSVDPGRLGMAPILLFFAVTFWVAAFDVYYAFQDMDFDAAFGLHSIPATFGTETALVLAAFSHAMTSIFLL
LSGFAAGLSWPWYVVWLGISLMLFVEHRLMRPQDLRHVNTAFFTLNGIISPVVLAGVILGIYL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=280, Percent_Identity=26.7857142857143, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1790473, Length=263, Percent_Identity=25.8555133079848, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17553718, Length=217, Percent_Identity=27.6497695852535, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324370, Length=275, Percent_Identity=24.3636363636364, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355567, Length=303, Percent_Identity=25.4125412541254, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33472; Mature: 33472

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFQNPLGRISPHLGRLSSPFGKFSDICRMIKIEHSIFALPYAWAGAFLAARGMPPAWSL
CCCCCCHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VFLTIAMVAARSFAMAFNRLVDLPFDSDNPRTQNRPLVTGVISTRQTWAFCGLMAVIFVV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
ACACMNQVCLWLSVPALVFSAIYSVLKRFTPLCHFWLGATLGLAPLAGWLSVDPGRLGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
PILLFFAVTFWVAAFDVYYAFQDMDFDAAFGLHSIPATFGTETALVLAAFSHAMTSIFLL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCHHCCHHHHHHHHHHHHHHHHHHH
LSGFAAGLSWPWYVVWLGISLMLFVEHRLMRPQDLRHVNTAFFTLNGIISPVVLAGVILG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYL
HCC
>Mature Secondary Structure
MRFQNPLGRISPHLGRLSSPFGKFSDICRMIKIEHSIFALPYAWAGAFLAARGMPPAWSL
CCCCCCHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VFLTIAMVAARSFAMAFNRLVDLPFDSDNPRTQNRPLVTGVISTRQTWAFCGLMAVIFVV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
ACACMNQVCLWLSVPALVFSAIYSVLKRFTPLCHFWLGATLGLAPLAGWLSVDPGRLGMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
PILLFFAVTFWVAAFDVYYAFQDMDFDAAFGLHSIPATFGTETALVLAAFSHAMTSIFLL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCCHHCCHHHHHHHHHHHHHHHHHHH
LSGFAAGLSWPWYVVWLGISLMLFVEHRLMRPQDLRHVNTAFFTLNGIISPVVLAGVILG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA