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The map label for this gene is fur [H]

Identifier: 220903878

GI number: 220903878

Start: 730348

End: 730812

Strand: Direct

Name: fur [H]

Synonym: Ddes_0603

Alternate gene names: 220903878

Gene position: 730348-730812 (Clockwise)

Preceding gene: 220903876

Following gene: 220903879

Centisome position: 25.42

GC content: 54.41

Gene sequence:

>465_bases
ATGACAGCAACACAGCTTAACGCCTGCCTGGCGGACTTTCTGGAGTTCATGAACCGCAAGGGCCTGAACACCACATCGCA
ACGGCGCATCATAGCCGAAGCCTTTTTTGAGCTGCCGGGCCACCACTCTCTTGAAGAGTTTTATCAACACATCCTGCAGC
GCGATCCGGGTATCGGGCAAACTACAGTATACCGTACCCTCAAGCTGCTCTGTGACGCCGGTATGGCTATGGAAATTCAC
TTCAGCGACGGAATCACCCGCTATGAAGTAGCCAGGCCCGACAGTCACCACGACCATCTGGTCTGTCTGCAGTGCGGCAA
GATCGTGGAAATCTGCGATCCACGCATTGAAACACTTCAGCGTGAAATGGCCGAAAAATACGGCTTCAGGCTGCGGGGCC
ATGTACACAACCTGTACGGCCTGTGCGAAATGTGCCGTACCCAGGCCGCTGAAGAAGACAAGTAA

Upstream 100 bases:

>100_bases
ATCTGAACATTTCAACATAACGGGCTCGAAAAACTCGCGCTTTGTTTTTCTTGGCATGAACGTGGAAAATATTTTACATT
GCTCCCGGGGGTAGGCAATT

Downstream 100 bases:

>100_bases
GAGTTTCATGCGGTTGCGGCAGGGGTGCAGTCTGCGTACCGCATGAAACTGCTTGCTGCTGGCGCAACAGGCTCGCCTGT
TGCGGTCCCTTACGCAGCCG

Product: Fur family ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTATQLNACLADFLEFMNRKGLNTTSQRRIIAEAFFELPGHHSLEEFYQHILQRDPGIGQTTVYRTLKLLCDAGMAMEIH
FSDGITRYEVARPDSHHDHLVCLQCGKIVEICDPRIETLQREMAEKYGFRLRGHVHNLYGLCEMCRTQAAEEDK

Sequences:

>Translated_154_residues
MTATQLNACLADFLEFMNRKGLNTTSQRRIIAEAFFELPGHHSLEEFYQHILQRDPGIGQTTVYRTLKLLCDAGMAMEIH
FSDGITRYEVARPDSHHDHLVCLQCGKIVEICDPRIETLQREMAEKYGFRLRGHVHNLYGLCEMCRTQAAEEDK
>Mature_153_residues
TATQLNACLADFLEFMNRKGLNTTSQRRIIAEAFFELPGHHSLEEFYQHILQRDPGIGQTTVYRTLKLLCDAGMAMEIHF
SDGITRYEVARPDSHHDHLVCLQCGKIVEICDPRIETLQREMAEKYGFRLRGHVHNLYGLCEMCRTQAAEEDK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=127, Percent_Identity=40.9448818897638, Blast_Score=94, Evalue=4e-21,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17758; Mature: 17626

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATQLNACLADFLEFMNRKGLNTTSQRRIIAEAFFELPGHHSLEEFYQHILQRDPGIGQ
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCH
TTVYRTLKLLCDAGMAMEIHFSDGITRYEVARPDSHHDHLVCLQCGKIVEICDPRIETLQ
HHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCEEEEHHCCHHHHHCHHHHHHH
REMAEKYGFRLRGHVHNLYGLCEMCRTQAAEEDK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TATQLNACLADFLEFMNRKGLNTTSQRRIIAEAFFELPGHHSLEEFYQHILQRDPGIGQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCH
TTVYRTLKLLCDAGMAMEIHFSDGITRYEVARPDSHHDHLVCLQCGKIVEICDPRIETLQ
HHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCEEEEHHCCHHHHHCHHHHHHH
REMAEKYGFRLRGHVHNLYGLCEMCRTQAAEEDK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]