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The map label for this gene is walR [H]

Identifier: 220903843

GI number: 220903843

Start: 686249

End: 686926

Strand: Direct

Name: walR [H]

Synonym: Ddes_0567

Alternate gene names: 220903843

Gene position: 686249-686926 (Clockwise)

Preceding gene: 220903839

Following gene: 220903844

Centisome position: 23.88

GC content: 63.27

Gene sequence:

>678_bases
ATGAGCCAACAGATATTGATAGTTGAAGATGAAGCCGACATTCGCGAGCTTTTGCGCTTTAATCTCGAGCGTGAGGGCTT
CAGCGTTCTGGAGGCGGCGGATGGCAACGAGGCGCTCAGGCTGGCCCGCCAGCATCTGCCGGACCTCATGCTGCTGGACG
TCATGATGCCCGGGCCGGACGGGTTCGAGATCTGCCGCCTTTTGGGGGCGCAGGCTGAAACCGCCCATATCCCCGTGCTT
ATGCTGACGGCCAGAGGCGAAGAAATGGACCGCGTGGTGGGCCTGAGCCTTGGCGCGGACGATTATGTGGTCAAACCTTT
CAGCGTGCGTGAGCTTATGCTGCGCATCCGGGCAGTGCTGCGGCGCGGGACGCGCAGCGGCGAAAGCCCGGTGCTGGAAC
GCCACGGCATACGCCTGCGCCCCGATGCCCATACGGCGGAGGCGCACGGCGAAGAACTGCAGTTGACAGCCACGGAGTTT
CGCCTGCTGGAAGACCTGCTGCGCCATGCCGGGTCGGTGCGCACGCGTGAGCAGCTGCTCAACAAGGTATGGGGCTATTC
CTTTGAAGGATATGCCCGCACGGTGGATACCCACGTGCGCCGCCTGCGCGCCAAGCTGGGGCATGCGGCCTCCATGCTGG
AGACCGTGCGCGGGGTAGGCTACAGGATAAAGGAATAG

Upstream 100 bases:

>100_bases
TTTTTCAGGCGGTTCGCCATGTCACGAAATTGTAACAGAGCTACCATCACATTGGCGCAAAGAGGCGGTTTACTCGGGCT
GCGTCACAGAGGTGTGCACT

Downstream 100 bases:

>100_bases
CCGCCTGGATCACGGGTAGGCTTGCCGGCCTGTGACGTGTCCGGGCAGATACGGCGGCACAGCCGCATTGGCGGAAGATA
TGCTTTCATTCAGAACCAGA

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSQQILIVEDEADIRELLRFNLEREGFSVLEAADGNEALRLARQHLPDLMLLDVMMPGPDGFEICRLLGAQAETAHIPVL
MLTARGEEMDRVVGLSLGADDYVVKPFSVRELMLRIRAVLRRGTRSGESPVLERHGIRLRPDAHTAEAHGEELQLTATEF
RLLEDLLRHAGSVRTREQLLNKVWGYSFEGYARTVDTHVRRLRAKLGHAASMLETVRGVGYRIKE

Sequences:

>Translated_225_residues
MSQQILIVEDEADIRELLRFNLEREGFSVLEAADGNEALRLARQHLPDLMLLDVMMPGPDGFEICRLLGAQAETAHIPVL
MLTARGEEMDRVVGLSLGADDYVVKPFSVRELMLRIRAVLRRGTRSGESPVLERHGIRLRPDAHTAEAHGEELQLTATEF
RLLEDLLRHAGSVRTREQLLNKVWGYSFEGYARTVDTHVRRLRAKLGHAASMLETVRGVGYRIKE
>Mature_224_residues
SQQILIVEDEADIRELLRFNLEREGFSVLEAADGNEALRLARQHLPDLMLLDVMMPGPDGFEICRLLGAQAETAHIPVLM
LTARGEEMDRVVGLSLGADDYVVKPFSVRELMLRIRAVLRRGTRSGESPVLERHGIRLRPDAHTAEAHGEELQLTATEFR
LLEDLLRHAGSVRTREQLLNKVWGYSFEGYARTVDTHVRRLRAKLGHAASMLETVRGVGYRIKE

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=48.2300884955752, Blast_Score=200, Evalue=5e-53,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=43.8053097345133, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=38.961038961039, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=44.5887445887446, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=37.5545851528384, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=37.2727272727273, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=37.6681614349776, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=38.3928571428571, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=34.7639484978541, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=38.2882882882883, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=38.4955752212389, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=32.4200913242009, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=33.7719298245614, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=32.1888412017167, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=30.8333333333333, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=106, Percent_Identity=39.622641509434, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25430; Mature: 25299

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQILIVEDEADIRELLRFNLEREGFSVLEAADGNEALRLARQHLPDLMLLDVMMPGPD
CCCCEEEEECCHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHCCHHEEHHHHCCCCC
GFEICRLLGAQAETAHIPVLMLTARGEEMDRVVGLSLGADDYVVKPFSVRELMLRIRAVL
HHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHH
RRGTRSGESPVLERHGIRLRPDAHTAEAHGEELQLTATEFRLLEDLLRHAGSVRTREQLL
HHCCCCCCCCHHHHCCCEECCCCCCHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHH
NKVWGYSFEGYARTVDTHVRRLRAKLGHAASMLETVRGVGYRIKE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SQQILIVEDEADIRELLRFNLEREGFSVLEAADGNEALRLARQHLPDLMLLDVMMPGPD
CCCEEEEECCHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHCCHHEEHHHHCCCCC
GFEICRLLGAQAETAHIPVLMLTARGEEMDRVVGLSLGADDYVVKPFSVRELMLRIRAVL
HHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHH
RRGTRSGESPVLERHGIRLRPDAHTAEAHGEELQLTATEFRLLEDLLRHAGSVRTREQLL
HHCCCCCCCCHHHHCCCEECCCCCCHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHH
NKVWGYSFEGYARTVDTHVRRLRAKLGHAASMLETVRGVGYRIKE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA