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The map label for this gene is hisK [H]

Identifier: 220903646

GI number: 220903646

Start: 444194

End: 445120

Strand: Direct

Name: hisK [H]

Synonym: Ddes_0366

Alternate gene names: 220903646

Gene position: 444194-445120 (Clockwise)

Preceding gene: 220903644

Following gene: 220903647

Centisome position: 15.46

GC content: 60.63

Gene sequence:

>927_bases
ATGAAGCATGGGCTTACAGATATGCGGATATTGCCGTATTCCGGCCGGGAGAGGGCCACGCCGCGGGTGGTTTTTGTCCG
GGCTTTGGCGTATGCACAGACGATGATACGCGCTGATCTGCATAACCACACCCTGGCCGCCCACGGCCAGGACACCGTGA
ATGACATGTATAAGGCGGCCAGCAAGCGACATGTGGACTGGTACGGCCTCTCCGAACATTCCCCCCTGCCGCCAGGTTAT
TCCTGCCCGCTCTACAAGGGGGACCTTAACGTGACCTTCCCCGCCTATGTGGAGGCTGTGCTGGCGCTCAAGGACAACGC
TTTGCCCGGCGGCCCCCGGGTGCTGCTCGGTATGGAGCTGGACTGGCTGCCCGTGAATATGGGGTGGATGGAAAGCCTGC
TGGGGCGATATCCCTTTGACTATGTTATCGGCGGGCTGCATTTTGTGCATGATGTACCCATAGGCTCTCCGCGCAGCTGG
GGCGAAGGTCTGGCCCTGCCGGAGCGCTTTGCCCGTTATGAAGCCTATTATGAAGAAATGGCCCGGCTTGCAGCCAGCGG
ATTTGTGGATGTGGTGGCTCATCCGGACTTTATCAAGGTCTGCTGCTATGACGATTTTCAGGACTGGCTGCGCCAGCCGG
GCAGCCTGGATATTGTGGCGCGCGCTCTTGAGGCCATGCGGCAGCAGGATGTCGCCATGGAGGTTTCTTCTGCCGGCTTG
CGAAAGGCTTTTCACGAGCCGTATCCCGGTCCGGCCATTATGGGCCTTGCCGCTGATCTGGGGCTGGATATCTGCTTTGG
TTCCGATGCCCACGCGGCCGCCGAAACCGTATCCCACTTCGACGATCTGGCGCGCTACGCCCGCTCGTACGGCTTCAGCC
GCAACCGCATAGCAGTAGGGCGGGAGCGGCGCTGGCTGGAATTCTGA

Upstream 100 bases:

>100_bases
GGCGTTGGCAAATGCTTTTCGGGCAGCTTTCGATGCCAGTATACAAAGCATTTTTTCTTTGTAAACGCTTTTGATTCCTT
ATACGAATATCGGCCGATGC

Downstream 100 bases:

>100_bases
CGCATAAGCCTCTTGAAGCAGTCCCTGGGGTATACCTGCGTTTCTTGCGGATCTGCCGGGTCGGCAAAGACTGTCTTCTG
TCCATTGCCCGGCCAACCCC

Product: histidinol phosphate phosphatase protein

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKHGLTDMRILPYSGRERATPRVVFVRALAYAQTMIRADLHNHTLAAHGQDTVNDMYKAASKRHVDWYGLSEHSPLPPGY
SCPLYKGDLNVTFPAYVEAVLALKDNALPGGPRVLLGMELDWLPVNMGWMESLLGRYPFDYVIGGLHFVHDVPIGSPRSW
GEGLALPERFARYEAYYEEMARLAASGFVDVVAHPDFIKVCCYDDFQDWLRQPGSLDIVARALEAMRQQDVAMEVSSAGL
RKAFHEPYPGPAIMGLAADLGLDICFGSDAHAAAETVSHFDDLARYARSYGFSRNRIAVGRERRWLEF

Sequences:

>Translated_308_residues
MKHGLTDMRILPYSGRERATPRVVFVRALAYAQTMIRADLHNHTLAAHGQDTVNDMYKAASKRHVDWYGLSEHSPLPPGY
SCPLYKGDLNVTFPAYVEAVLALKDNALPGGPRVLLGMELDWLPVNMGWMESLLGRYPFDYVIGGLHFVHDVPIGSPRSW
GEGLALPERFARYEAYYEEMARLAASGFVDVVAHPDFIKVCCYDDFQDWLRQPGSLDIVARALEAMRQQDVAMEVSSAGL
RKAFHEPYPGPAIMGLAADLGLDICFGSDAHAAAETVSHFDDLARYARSYGFSRNRIAVGRERRWLEF
>Mature_308_residues
MKHGLTDMRILPYSGRERATPRVVFVRALAYAQTMIRADLHNHTLAAHGQDTVNDMYKAASKRHVDWYGLSEHSPLPPGY
SCPLYKGDLNVTFPAYVEAVLALKDNALPGGPRVLLGMELDWLPVNMGWMESLLGRYPFDYVIGGLHFVHDVPIGSPRSW
GEGLALPERFARYEAYYEEMARLAASGFVDVVAHPDFIKVCCYDDFQDWLRQPGSLDIVARALEAMRQQDVAMEVSSAGL
RKAFHEPYPGPAIMGLAADLGLDICFGSDAHAAAETVSHFDDLARYARSYGFSRNRIAVGRERRWLEF

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 34497; Mature: 34497

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHGLTDMRILPYSGRERATPRVVFVRALAYAQTMIRADLHNHTLAAHGQDTVNDMYKAA
CCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHH
SKRHVDWYGLSEHSPLPPGYSCPLYKGDLNVTFPAYVEAVLALKDNALPGGPRVLLGMEL
HHCCCCEECCCCCCCCCCCCCCCEEECCCCEECHHHHHHHHHHHCCCCCCCCEEEEEEEE
DWLPVNMGWMESLLGRYPFDYVIGGLHFVHDVPIGSPRSWGEGLALPERFARYEAYYEEM
CEEECCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ARLAASGFVDVVAHPDFIKVCCYDDFQDWLRQPGSLDIVARALEAMRQQDVAMEVSSAGL
HHHHHCCCCCEEECCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKAFHEPYPGPAIMGLAADLGLDICFGSDAHAAAETVSHFDDLARYARSYGFSRNRIAVG
HHHHCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
RERRWLEF
CCCCCCCC
>Mature Secondary Structure
MKHGLTDMRILPYSGRERATPRVVFVRALAYAQTMIRADLHNHTLAAHGQDTVNDMYKAA
CCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHH
SKRHVDWYGLSEHSPLPPGYSCPLYKGDLNVTFPAYVEAVLALKDNALPGGPRVLLGMEL
HHCCCCEECCCCCCCCCCCCCCCEEECCCCEECHHHHHHHHHHHCCCCCCCCEEEEEEEE
DWLPVNMGWMESLLGRYPFDYVIGGLHFVHDVPIGSPRSWGEGLALPERFARYEAYYEEM
CEEECCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ARLAASGFVDVVAHPDFIKVCCYDDFQDWLRQPGSLDIVARALEAMRQQDVAMEVSSAGL
HHHHHCCCCCEEECCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RKAFHEPYPGPAIMGLAADLGLDICFGSDAHAAAETVSHFDDLARYARSYGFSRNRIAVG
HHHHCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
RERRWLEF
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]