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The map label for this gene is flhA [H]

Identifier: 220903611

GI number: 220903611

Start: 401682

End: 403781

Strand: Reverse

Name: flhA [H]

Synonym: Ddes_0331

Alternate gene names: 220903611

Gene position: 403781-401682 (Counterclockwise)

Preceding gene: 220903612

Following gene: 220903608

Centisome position: 14.05

GC content: 59.0

Gene sequence:

>2100_bases
ATGGCTTCAGCAAGCCTTCCCAAGCTCGACTACAGCAGATTTTCCCGTAACGGAGAAATCATGCTCGCCGCCGGCGTGGT
CATCATCCTTCTGGTCATGCTGGTTCCGCTGCCCACATTTTTTCTCGACATCATGCTCTGCGTGAGCATTTCCATATCCT
TGCTGGTGCTCATTACCACCATGTTCATGAGCTCCCCGCTGGAGTTCACCATCTTTCCGTCATTGCTGCTGGTGACCACC
CTGCTGCGCCTTTCGCTCAACGTGGCCGCTACCCGGCTCATCCTGCTCAACGGCGACATGGGCGTTGACGCCGCAGGCTC
GGTCATCCGCGCTTTCGGCGAATTTGTCGTGGGCGGCAGCTACGTGGTGGGCGCGGTCATATTCATGATCCTGTTCATTC
TCAACAAGGTGGTCATCACTGCGGGTACCACGCGCATCGCCGAAGTGGCGGCCCGTTTTACCCTGGACGCCATGCCCGGC
AAGCAGATGGCTATTGAAGCCGACCTCAACGCCGGGCTTATTGATGAAGAAGAAGCCACCGCCCGCCGCAAGGGCATGCG
CAAGGAAGCAGACTTTTACGGCGCCATGGACGGTGCGTGCAAATTTGTTTCGGGCGACGTCAACGCGGGCATGTTCATTA
CCATCGTCAACATTGTGGGTGGCATCATCATCGGCATGGTGCAGAAGGATATGGACTGGAACACGGCCCTGATGACCTAT
TCGCTGCTGACCATCGGCGACGGTCTCGTGTCGACCATACCATCCATCATCGTCTCCACGGGAACAGGCCTGCTGGTCTC
ACGAGCGGCTTCCGAAGCCAAGATGGGTGAGGAATTTCTGGCCCAGCTTACCTTCAACAGCCGGGCGCTCAAGATGGTTT
CGGCCGTGCTGCTGCTCTTTGCCATTGTTCCCGGTCTGCCCACCATCCCCTTTCTGGTCATCGCCGGCCTTATTTTCACG
GTGGCGCGCCTCACGGAGAAAAATGATGCCGATGAAGAAGCCAGGGAGCGCAAGGAAAAGAATGCCAAGGCCGGGTCCGG
CACTGCCGATACTCCCGAAGAAGTACAGGCCCTTCTGCCCCTGGATACGCTTGAACTGGAGGTGGGCTACGGCCTTATTC
CTCTGGTTGACGAAGAGCAGAGCGGCAACCTGCTGGCGCGCATACGCTCCATCCGGCGGCAGTTCGCGCTGGATATGGGG
GTGGTCATTCCTTCGCTGCACCTGCGTGACAACCTGCAGCTCAAGCCCGGCCAGTATTCACTGCTGATCAAAGGCAACCA
GGTGGCTTCGGCGGAAATTCTGGTAGACCATTTTCTGGCTATGGACCCCGGCAACGTGACCACCAAGATTCACGGCATAG
AAACGCGCGAACCGGCCTTTAACCTGCCCGCGCTCTGGATACCCGACAGCCAGCGCGAAGAAGCCATGCTGGCGGGCTAC
ACTGTGGTGGACCCGGCAACGGTCATTGCCACGCACCTGACAGAAGTGTTCAAACGTCATCTGTCCGACTTCCTTGACCG
TCAGGCAGTTCAGGGCCTGCTGGACACGGTGGCCAAGCATTCGCCCAAGGCAGTGGAAGACCTTGTACCCGGCGTGCTGC
CCCTCGGCACTGTGCAAAAGGTACTGCAACTGCTGGTGCGCGAAAACGTGAGCATACGCGACATGCTCACCATTGTGGAA
ACACTGGGCGACTTTGGCGCAGGCGTAAAAAACCCCGACATGCTGACGGAATACGTTCGCGAAAAGCTGGCGCGATCCAT
CGTGCGCCCCTATCTGGACAGCCAGGGAACGCTGCCCGTGCTCACCCTTGCCCCCAATGCCGAACGTATGGTGCAGGAAG
GCGTGCGCCAGGCAGATACAGGAGCGACCTTTCTTTCGCTCAACCCCGCTTCGGCCCAGCGGCTGGTGCAGAACATCAGT
GCAGCCGTGGAAAACGCCGTCAACACGGACGGCCAGCCCGTACTGCTGGTGAACCCTGTCATACGGCCGCATCTGGCCCA
GCTTGTCACGCGCTTTCTGCCTTCTGTGCCGGTTATTTCGCAAGCCGAAATTCCGCCGGACATCCGCCTTCAGGCTGTGG
GGAGCGTTGCTGCGGAATAG

Upstream 100 bases:

>100_bases
TGTGCTGGCCGCCATCTGGAAGCTCAAGCCAAAGGTGCATAATTCATAGTTTTTCCAGCGTGCGTGCCAAAACAGGGCGC
AGAAGCGAGGTGTCAGAAAA

Downstream 100 bases:

>100_bases
GGCGCACACTGCATGAGCAAAACCGTAAAAAGGTGACAGCCTTTATATACAGCGCTGTTACACAAAAGGGTTCATAATCA
GTTCACTGATTATGAACCCT

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MASASLPKLDYSRFSRNGEIMLAAGVVIILLVMLVPLPTFFLDIMLCVSISISLLVLITTMFMSSPLEFTIFPSLLLVTT
LLRLSLNVAATRLILLNGDMGVDAAGSVIRAFGEFVVGGSYVVGAVIFMILFILNKVVITAGTTRIAEVAARFTLDAMPG
KQMAIEADLNAGLIDEEEATARRKGMRKEADFYGAMDGACKFVSGDVNAGMFITIVNIVGGIIIGMVQKDMDWNTALMTY
SLLTIGDGLVSTIPSIIVSTGTGLLVSRAASEAKMGEEFLAQLTFNSRALKMVSAVLLLFAIVPGLPTIPFLVIAGLIFT
VARLTEKNDADEEARERKEKNAKAGSGTADTPEEVQALLPLDTLELEVGYGLIPLVDEEQSGNLLARIRSIRRQFALDMG
VVIPSLHLRDNLQLKPGQYSLLIKGNQVASAEILVDHFLAMDPGNVTTKIHGIETREPAFNLPALWIPDSQREEAMLAGY
TVVDPATVIATHLTEVFKRHLSDFLDRQAVQGLLDTVAKHSPKAVEDLVPGVLPLGTVQKVLQLLVRENVSIRDMLTIVE
TLGDFGAGVKNPDMLTEYVREKLARSIVRPYLDSQGTLPVLTLAPNAERMVQEGVRQADTGATFLSLNPASAQRLVQNIS
AAVENAVNTDGQPVLLVNPVIRPHLAQLVTRFLPSVPVISQAEIPPDIRLQAVGSVAAE

Sequences:

>Translated_699_residues
MASASLPKLDYSRFSRNGEIMLAAGVVIILLVMLVPLPTFFLDIMLCVSISISLLVLITTMFMSSPLEFTIFPSLLLVTT
LLRLSLNVAATRLILLNGDMGVDAAGSVIRAFGEFVVGGSYVVGAVIFMILFILNKVVITAGTTRIAEVAARFTLDAMPG
KQMAIEADLNAGLIDEEEATARRKGMRKEADFYGAMDGACKFVSGDVNAGMFITIVNIVGGIIIGMVQKDMDWNTALMTY
SLLTIGDGLVSTIPSIIVSTGTGLLVSRAASEAKMGEEFLAQLTFNSRALKMVSAVLLLFAIVPGLPTIPFLVIAGLIFT
VARLTEKNDADEEARERKEKNAKAGSGTADTPEEVQALLPLDTLELEVGYGLIPLVDEEQSGNLLARIRSIRRQFALDMG
VVIPSLHLRDNLQLKPGQYSLLIKGNQVASAEILVDHFLAMDPGNVTTKIHGIETREPAFNLPALWIPDSQREEAMLAGY
TVVDPATVIATHLTEVFKRHLSDFLDRQAVQGLLDTVAKHSPKAVEDLVPGVLPLGTVQKVLQLLVRENVSIRDMLTIVE
TLGDFGAGVKNPDMLTEYVREKLARSIVRPYLDSQGTLPVLTLAPNAERMVQEGVRQADTGATFLSLNPASAQRLVQNIS
AAVENAVNTDGQPVLLVNPVIRPHLAQLVTRFLPSVPVISQAEIPPDIRLQAVGSVAAE
>Mature_698_residues
ASASLPKLDYSRFSRNGEIMLAAGVVIILLVMLVPLPTFFLDIMLCVSISISLLVLITTMFMSSPLEFTIFPSLLLVTTL
LRLSLNVAATRLILLNGDMGVDAAGSVIRAFGEFVVGGSYVVGAVIFMILFILNKVVITAGTTRIAEVAARFTLDAMPGK
QMAIEADLNAGLIDEEEATARRKGMRKEADFYGAMDGACKFVSGDVNAGMFITIVNIVGGIIIGMVQKDMDWNTALMTYS
LLTIGDGLVSTIPSIIVSTGTGLLVSRAASEAKMGEEFLAQLTFNSRALKMVSAVLLLFAIVPGLPTIPFLVIAGLIFTV
ARLTEKNDADEEARERKEKNAKAGSGTADTPEEVQALLPLDTLELEVGYGLIPLVDEEQSGNLLARIRSIRRQFALDMGV
VIPSLHLRDNLQLKPGQYSLLIKGNQVASAEILVDHFLAMDPGNVTTKIHGIETREPAFNLPALWIPDSQREEAMLAGYT
VVDPATVIATHLTEVFKRHLSDFLDRQAVQGLLDTVAKHSPKAVEDLVPGVLPLGTVQKVLQLLVRENVSIRDMLTIVET
LGDFGAGVKNPDMLTEYVREKLARSIVRPYLDSQGTLPVLTLAPNAERMVQEGVRQADTGATFLSLNPASAQRLVQNISA
AVENAVNTDGQPVLLVNPVIRPHLAQLVTRFLPSVPVISQAEIPPDIRLQAVGSVAAE

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=687, Percent_Identity=42.5036390101892, Blast_Score=533, Evalue=1e-152,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75294; Mature: 75163

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASASLPKLDYSRFSRNGEIMLAAGVVIILLVMLVPLPTFFLDIMLCVSISISLLVLITT
CCCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MFMSSPLEFTIFPSLLLVTTLLRLSLNVAATRLILLNGDMGVDAAGSVIRAFGEFVVGGS
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHCCCH
YVVGAVIFMILFILNKVVITAGTTRIAEVAARFTLDAMPGKQMAIEADLNAGLIDEEEAT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHH
ARRKGMRKEADFYGAMDGACKFVSGDVNAGMFITIVNIVGGIIIGMVQKDMDWNTALMTY
HHHHCCCHHHHHHCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SLLTIGDGLVSTIPSIIVSTGTGLLVSRAASEAKMGEEFLAQLTFNSRALKMVSAVLLLF
HHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AIVPGLPTIPFLVIAGLIFTVARLTEKNDADEEARERKEKNAKAGSGTADTPEEVQALLP
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
LDTLELEVGYGLIPLVDEEQSGNLLARIRSIRRQFALDMGVVIPSLHLRDNLQLKPGQYS
CCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEE
LLIKGNQVASAEILVDHFLAMDPGNVTTKIHGIETREPAFNLPALWIPDSQREEAMLAGY
EEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCCCHHHCCC
TVVDPATVIATHLTEVFKRHLSDFLDRQAVQGLLDTVAKHSPKAVEDLVPGVLPLGTVQK
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
VLQLLVRENVSIRDMLTIVETLGDFGAGVKNPDMLTEYVREKLARSIVRPYLDSQGTLPV
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LTLAPNAERMVQEGVRQADTGATFLSLNPASAQRLVQNISAAVENAVNTDGQPVLLVNPV
EEECCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCH
IRPHLAQLVTRFLPSVPVISQAEIPPDIRLQAVGSVAAE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
ASASLPKLDYSRFSRNGEIMLAAGVVIILLVMLVPLPTFFLDIMLCVSISISLLVLITT
CCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MFMSSPLEFTIFPSLLLVTTLLRLSLNVAATRLILLNGDMGVDAAGSVIRAFGEFVVGGS
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHCCCH
YVVGAVIFMILFILNKVVITAGTTRIAEVAARFTLDAMPGKQMAIEADLNAGLIDEEEAT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHH
ARRKGMRKEADFYGAMDGACKFVSGDVNAGMFITIVNIVGGIIIGMVQKDMDWNTALMTY
HHHHCCCHHHHHHCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
SLLTIGDGLVSTIPSIIVSTGTGLLVSRAASEAKMGEEFLAQLTFNSRALKMVSAVLLLF
HHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AIVPGLPTIPFLVIAGLIFTVARLTEKNDADEEARERKEKNAKAGSGTADTPEEVQALLP
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
LDTLELEVGYGLIPLVDEEQSGNLLARIRSIRRQFALDMGVVIPSLHLRDNLQLKPGQYS
CCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEE
LLIKGNQVASAEILVDHFLAMDPGNVTTKIHGIETREPAFNLPALWIPDSQREEAMLAGY
EEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEECCCCCCCCHHHCCC
TVVDPATVIATHLTEVFKRHLSDFLDRQAVQGLLDTVAKHSPKAVEDLVPGVLPLGTVQK
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHH
VLQLLVRENVSIRDMLTIVETLGDFGAGVKNPDMLTEYVREKLARSIVRPYLDSQGTLPV
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LTLAPNAERMVQEGVRQADTGATFLSLNPASAQRLVQNISAAVENAVNTDGQPVLLVNPV
EEECCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCH
IRPHLAQLVTRFLPSVPVISQAEIPPDIRLQAVGSVAAE
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]