Click here to switch to the map view.

The map label for this gene is argB [H]

Identifier: 220903474

GI number: 220903474

Start: 240081

End: 240863

Strand: Reverse

Name: argB [H]

Synonym: Ddes_0190

Alternate gene names: 220903474

Gene position: 240863-240081 (Counterclockwise)

Preceding gene: 220903477

Following gene: 220903469

Centisome position: 8.38

GC content: 63.73

Gene sequence:

>783_bases
ATGAACAACGCCACGGTTGTCATCAAATATGGCGGACACGCCATGGACAAGCCCGACCTGTGCACAGCTTTTGCTACAGA
CCTCGCCCAGCTTTCGGCCCAGAGTATGGGCTTTGTCGTCGTACACGGCGGCGGACCGCAGATTTCCGCCCTGCTGCAAC
GCCTGAGTATTGAAAGCCGCTTTGAAAACGGCCTGCGCGTTACCGACCAACCCACTATGGAAGCGGTAGAAATGGTGCTG
TGCGGCCAGGTAAACAAGGCCGTGGTGGCCTCTCTGGCCGCGCACGGCGTGCGCAGCGCCGGAATTTCGGGCCGGGACGG
CAACCTTTTGCGCGCCGCCATAAAAAACCCCGCACTGGGCCTTGTAGGCGAAGTGGAAGCTGTGGACCCGGCCCTGCCCC
GTTGCCTGCTTGAAGCGGGCTTTGTACCCGTAGTCGCCCCGGTGGCCGGAGGTGCAGACGGGCAGGCACTGAACATCAAT
GCCGACACTGCCGCCGGAGCGCTGGCCGGGGCGCTGGCCGCAGACTACTTCGTGCTTATTTCCGACGTGCCGGGCGTACT
GGATGCCGAGGGCAGGCTCATACCCGCCCTGACGCGCAAAGAGATAGAAAACCTGTGCGCTGAAGGCGTTATCACGGGCG
GCATGATCCCCAAGGTGGAATCCTGCCTGCACGCCCTGGACTCGGGCTGCCGCCGCGCGCTCATCCTGGACGGGCGGGCG
CCTTCAAGCCTGCGCCGCTATCTGCTGGATGACGCCCCCCTAGGAACCGTGGTCATCGGCTGA

Upstream 100 bases:

>100_bases
ACCCGGCGCGCTTGCGTGCCGCATGGCGGAATGGTAATTTTGGCAGTCACCAGACACATTATAGAGCGATGCCTCACGCG
GCCGCAAATAAGGAATACGC

Downstream 100 bases:

>100_bases
TCCGTGCCGCGCCTGGCGCGGCACGCCTGAAACAGAAGCCCTTGGGCGGTCTTTTGCCATCCGCGCCGCTTGCGGCGCGG
ATATTCTTTTGCATGGCCTG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNNATVVIKYGGHAMDKPDLCTAFATDLAQLSAQSMGFVVVHGGGPQISALLQRLSIESRFENGLRVTDQPTMEAVEMVL
CGQVNKAVVASLAAHGVRSAGISGRDGNLLRAAIKNPALGLVGEVEAVDPALPRCLLEAGFVPVVAPVAGGADGQALNIN
ADTAAGALAGALAADYFVLISDVPGVLDAEGRLIPALTRKEIENLCAEGVITGGMIPKVESCLHALDSGCRRALILDGRA
PSSLRRYLLDDAPLGTVVIG

Sequences:

>Translated_260_residues
MNNATVVIKYGGHAMDKPDLCTAFATDLAQLSAQSMGFVVVHGGGPQISALLQRLSIESRFENGLRVTDQPTMEAVEMVL
CGQVNKAVVASLAAHGVRSAGISGRDGNLLRAAIKNPALGLVGEVEAVDPALPRCLLEAGFVPVVAPVAGGADGQALNIN
ADTAAGALAGALAADYFVLISDVPGVLDAEGRLIPALTRKEIENLCAEGVITGGMIPKVESCLHALDSGCRRALILDGRA
PSSLRRYLLDDAPLGTVVIG
>Mature_260_residues
MNNATVVIKYGGHAMDKPDLCTAFATDLAQLSAQSMGFVVVHGGGPQISALLQRLSIESRFENGLRVTDQPTMEAVEMVL
CGQVNKAVVASLAAHGVRSAGISGRDGNLLRAAIKNPALGLVGEVEAVDPALPRCLLEAGFVPVVAPVAGGADGQALNIN
ADTAAGALAGALAADYFVLISDVPGVLDAEGRLIPALTRKEIENLCAEGVITGGMIPKVESCLHALDSGCRRALILDGRA
PSSLRRYLLDDAPLGTVVIG

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI145693208, Length=255, Percent_Identity=34.1176470588235, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789181, Length=270, Percent_Identity=24.8148148148148, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320913, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 26683; Mature: 26683

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNATVVIKYGGHAMDKPDLCTAFATDLAQLSAQSMGFVVVHGGGPQISALLQRLSIESR
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHH
FENGLRVTDQPTMEAVEMVLCGQVNKAVVASLAAHGVRSAGISGRDGNLLRAAIKNPALG
HCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCC
LVGEVEAVDPALPRCLLEAGFVPVVAPVAGGADGQALNINADTAAGALAGALAADYFVLI
CCCCCHHCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHEE
SDVPGVLDAEGRLIPALTRKEIENLCAEGVITGGMIPKVESCLHALDSGCRRALILDGRA
ECCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
PSSLRRYLLDDAPLGTVVIG
HHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure
MNNATVVIKYGGHAMDKPDLCTAFATDLAQLSAQSMGFVVVHGGGPQISALLQRLSIESR
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHH
FENGLRVTDQPTMEAVEMVLCGQVNKAVVASLAAHGVRSAGISGRDGNLLRAAIKNPALG
HCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCC
LVGEVEAVDPALPRCLLEAGFVPVVAPVAGGADGQALNINADTAAGALAGALAADYFVLI
CCCCCHHCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHEE
SDVPGVLDAEGRLIPALTRKEIENLCAEGVITGGMIPKVESCLHALDSGCRRALILDGRA
ECCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
PSSLRRYLLDDAPLGTVVIG
HHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA