Click here to switch to the map view.

The map label for this gene is 220903411

Identifier: 220903411

GI number: 220903411

Start: 161550

End: 162761

Strand: Reverse

Name: 220903411

Synonym: Ddes_0125

Alternate gene names: NA

Gene position: 162761-161550 (Counterclockwise)

Preceding gene: 220903412

Following gene: 220903410

Centisome position: 5.66

GC content: 58.5

Gene sequence:

>1212_bases
ATGGCGAATATCCTTATCATCGGCGCGGGTGGCGTCGGGAGCGTGGTTGTCCACAAATGCGCCCAGGTTGCCGCAAACGG
CGGCGTTTTTAACAAGATAACCCTTGCCAGCCGCACGGTCTCCCGCTGCGATGCCATTGCGCAAAGCGTAAAGGCCCGCT
ACGGCGTTGACGTGGCTACCGCCAAGGTGGACGCGGACAACGTGCCGGAGCTTTGCCAGCTTATCCGCAGCGTCAAGCCC
GACCTTGTGTGCAACGTGGCCCTGCCCTACCAGGACCTGCACATAATGGATGCCTGCCTTGAATGCGGCGTTCATTATGT
GGACACCGCCAACTATGAGCCGCTGGACACCGCCAAGTTTGAATACAAATGGCAGTGGGCCTATGCCGACCGCTTTCGCG
AGGCCGGGCTTACCGCCCTGCTCGGTTCCGGCTTTGACCCCGGCGTGACCAACGTCTTTGCCGCCTGGGTCATGAAGCAC
GAACTGGACGAAGTGCATGTGCTCGACATCATCGACTGCAATGCCGGCGACCACGGCCAGCCCTTTGCCACCAACTTCAA
CCCCGAAATCAACATCCGCGAGGTCACCGCGCGCGGCCGCTACTGGGAACGGGGCGAATGGGTAGAAACCGACCCCCTGT
CCTGGTCAATGAACTTTGACTTCCCCAGCGGCATCGGCAGCAAAAAATGCTTTCTCATGTATCATGAAGAGCTGGAATCT
CTGGTCAAAAACCTCAAGGGCCTGCGCCGCGCCCGCTTCTGGATGACGTTTTCAGACAACTACCTCAACCACCTGAAGGT
ACTTGGCAATGTGGGCATGACCCGCATTGATCCCGTGAACTTTCAGGGGCAGGACATCGTACCCATCCAATTCCTGTCCA
AACTTTTGCCCGACCCTGCCTCCCTCGGCCCCCTGACCAAGGGCAAGACCTGCATTGGCGACCTCATGCGCGGCGTCAAG
GACGGCAAAGAAAAAACCGTTTACATCTATAACATCTGCGATCACGAAGCATGCTACGCCGAAGTCGGCTCGCAGGCCAT
TTCCTACACCACCGGCGTGCCTGCCATGATCGGCTCCAAAATGGTGGCCGAAGGCGTGTGGCGCAAGCCCGGCGTGTGGA
ATATGGAGCAGTTTGACCCCGACCCCTTCCTGAAGGATCTGGGTACATACGGCCTGCCCTGGCAGTCCGTGGATGTGACC
GGAAAAATATAA

Upstream 100 bases:

>100_bases
AGACCGCGCCGAGGCGCTTTTTGTGTGATGGGACGTGACCGGGCGGCGCAGCCGCACGGATTTTCTTTTGACCCCCTATC
TTGCTGGAGAGGGAAGAGCT

Downstream 100 bases:

>100_bases
GGGGACGCCTGAGCGGCCAGGAAATGAGAGAAAGGGCTTGCCCTTCGGGAAGAAAACACATGCCCTGCGGGCACGAAAAC
TTTTTCCCTGTTCTTCATTC

Product: Saccharopine dehydrogenase

Products: L-lysine; 2-oxoglutarate; NADH; H+

Alternate protein names: Carboxynorspermidine Dehydrogenase; Saccharopine Dehydrogenase-Like Protein; Carboxynorspermide Hydratase; Saccharopine Dehydrogenase Family Protein; Acyl Carrier Protein

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MANILIIGAGGVGSVVVHKCAQVAANGGVFNKITLASRTVSRCDAIAQSVKARYGVDVATAKVDADNVPELCQLIRSVKP
DLVCNVALPYQDLHIMDACLECGVHYVDTANYEPLDTAKFEYKWQWAYADRFREAGLTALLGSGFDPGVTNVFAAWVMKH
ELDEVHVLDIIDCNAGDHGQPFATNFNPEINIREVTARGRYWERGEWVETDPLSWSMNFDFPSGIGSKKCFLMYHEELES
LVKNLKGLRRARFWMTFSDNYLNHLKVLGNVGMTRIDPVNFQGQDIVPIQFLSKLLPDPASLGPLTKGKTCIGDLMRGVK
DGKEKTVYIYNICDHEACYAEVGSQAISYTTGVPAMIGSKMVAEGVWRKPGVWNMEQFDPDPFLKDLGTYGLPWQSVDVT
GKI

Sequences:

>Translated_403_residues
MANILIIGAGGVGSVVVHKCAQVAANGGVFNKITLASRTVSRCDAIAQSVKARYGVDVATAKVDADNVPELCQLIRSVKP
DLVCNVALPYQDLHIMDACLECGVHYVDTANYEPLDTAKFEYKWQWAYADRFREAGLTALLGSGFDPGVTNVFAAWVMKH
ELDEVHVLDIIDCNAGDHGQPFATNFNPEINIREVTARGRYWERGEWVETDPLSWSMNFDFPSGIGSKKCFLMYHEELES
LVKNLKGLRRARFWMTFSDNYLNHLKVLGNVGMTRIDPVNFQGQDIVPIQFLSKLLPDPASLGPLTKGKTCIGDLMRGVK
DGKEKTVYIYNICDHEACYAEVGSQAISYTTGVPAMIGSKMVAEGVWRKPGVWNMEQFDPDPFLKDLGTYGLPWQSVDVT
GKI
>Mature_402_residues
ANILIIGAGGVGSVVVHKCAQVAANGGVFNKITLASRTVSRCDAIAQSVKARYGVDVATAKVDADNVPELCQLIRSVKPD
LVCNVALPYQDLHIMDACLECGVHYVDTANYEPLDTAKFEYKWQWAYADRFREAGLTALLGSGFDPGVTNVFAAWVMKHE
LDEVHVLDIIDCNAGDHGQPFATNFNPEINIREVTARGRYWERGEWVETDPLSWSMNFDFPSGIGSKKCFLMYHEELESL
VKNLKGLRRARFWMTFSDNYLNHLKVLGNVGMTRIDPVNFQGQDIVPIQFLSKLLPDPASLGPLTKGKTCIGDLMRGVKD
GKEKTVYIYNICDHEACYAEVGSQAISYTTGVPAMIGSKMVAEGVWRKPGVWNMEQFDPDPFLKDLGTYGLPWQSVDVTG
KI

Specific function: Unknown

COG id: COG1748

COG function: function code E; Saccharopine dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.1.7

Molecular weight: Translated: 44659; Mature: 44527

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILIIGAGGVGSVVVHKCAQVAANGGVFNKITLASRTVSRCDAIAQSVKARYGVDVAT
CCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEE
AKVDADNVPELCQLIRSVKPDLVCNVALPYQDLHIMDACLECGVHYVDTANYEPLDTAKF
EECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEE
EYKWQWAYADRFREAGLTALLGSGFDPGVTNVFAAWVMKHELDEVHVLDIIDCNAGDHGQ
EEEEEEHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
PFATNFNPEINIREVTARGRYWERGEWVETDPLSWSMNFDFPSGIGSKKCFLMYHEELES
CCCCCCCCCEEEEEEEECCCCCCCCCEEECCCCEEEECCCCCCCCCCCEEEEEEHHHHHH
LVKNLKGLRRARFWMTFSDNYLNHLKVLGNVGMTRIDPVNFQGQDIVPIQFLSKLLPDPA
HHHHHHHHHHHHEEEEECHHHHHHHHHHHCCCCCEECCCCCCCCCEEHHHHHHHHCCCCC
SLGPLTKGKTCIGDLMRGVKDGKEKTVYIYNICDHEACYAEVGSQAISYTTGVPAMIGSK
CCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCHHHHHCCCCHHHHHHH
MVAEGVWRKPGVWNMEQFDPDPFLKDLGTYGLPWQSVDVTGKI
HHHHCCCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ANILIIGAGGVGSVVVHKCAQVAANGGVFNKITLASRTVSRCDAIAQSVKARYGVDVAT
CEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEE
AKVDADNVPELCQLIRSVKPDLVCNVALPYQDLHIMDACLECGVHYVDTANYEPLDTAKF
EECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEE
EYKWQWAYADRFREAGLTALLGSGFDPGVTNVFAAWVMKHELDEVHVLDIIDCNAGDHGQ
EEEEEEHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
PFATNFNPEINIREVTARGRYWERGEWVETDPLSWSMNFDFPSGIGSKKCFLMYHEELES
CCCCCCCCCEEEEEEEECCCCCCCCCEEECCCCEEEECCCCCCCCCCCEEEEEEHHHHHH
LVKNLKGLRRARFWMTFSDNYLNHLKVLGNVGMTRIDPVNFQGQDIVPIQFLSKLLPDPA
HHHHHHHHHHHHEEEEECHHHHHHHHHHHCCCCCEECCCCCCCCCEEHHHHHHHHCCCCC
SLGPLTKGKTCIGDLMRGVKDGKEKTVYIYNICDHEACYAEVGSQAISYTTGVPAMIGSK
CCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHCCHHHHHCCCCHHHHHHH
MVAEGVWRKPGVWNMEQFDPDPFLKDLGTYGLPWQSVDVTGKI
HHHHCCCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N6-(L-1,3-dicarboxypropyl)-L-lysine; NAD+; H2O

Specific reaction: N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA