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The map label for this gene is ykoW [H]

Identifier: 218906527

GI number: 218906527

Start: 5138493

End: 5140700

Strand: Direct

Name: ykoW [H]

Synonym: BCAH820_5441

Alternate gene names: 218906527

Gene position: 5138493-5140700 (Clockwise)

Preceding gene: 218906526

Following gene: 218906534

Centisome position: 96.9

GC content: 33.65

Gene sequence:

>2208_bases
ATGTTAACAACAGATACTTGGGTTTTAATTGGATATTTTATTGCACAATCATTAGTAATTTACGCCGTAATTAGTCTATA
TAGAAGAGAAGAATATTCTTCTAGCAGAATTTCATTAATTATCGGCTTTACTATTATACTCGTGTACGGATATATACACC
TGTTTCAATTAAACGCAGGGATAAAACCTTCTTCTGAAGTCTCTTACTTAATACATACTGCTTCAATTTTATTAATCGGT
TTGTCGTCCATACTATATATTTTAGATAAACCAATACAGCACGAAACGAAAACAAAGTATTATCGATTTGATTATGTGCG
CTTCATATTACCCTATTTTAGTATAATCATTACTTTTTCTTTTATTATCTTTCAACCTTGGGATGATAAGTTCATGTTAA
TCGGTCTAGTATTATCACTCATCTTATTATTCTTACGACAACTTTATATGTGGAAAGATAATCAGGCACTAATCGATACA
TACGAACAGCTGACTACACAACTAGAAGGCAAAGTAGAAGAAGGGGCATCTGCGTTATCAAAGAGTGAACAACGTTATAA
ATCTTTATTCGAAGATCACCCGGATGCTGTTTTCTCTTTAAATATGTATGGTATTTTCCAACAATCTAATACAGCTTGTG
AAAGCTTATTTACTGCCTACTATTGTGAAGTAGAAAGCTATTCTCTTTTACACTTTATTGACCCAAAAGACCATGATTTA
CTACAGAAAGCTTTACAACTAACGAAAGAAGGTAGCCCACAAACTTTAGAAGTTCGTACAAAAGAAAAAGAAGGTTATTA
CTATTACCTTCACATTACACTCATCCCTACTTTCATAAACAAAGAAGTTGTCGGGATGTTCGGTATAGCACGTGATATTA
CAACTTTATATGAAAAACAAAAACAAGTAGAACATTTAGCCTTTCATGATGCACTTACCGGATTACCAAATCGCCGCAAG
TTTGAAAAAGATTTAAAAAATATTTTAAATACAGCTCAGGCTAGCGCAAATGATGTTGCCGTCATGTTCCTTGATTTAGA
TCGATTCAAAAAAATTAACGATAGACTCGGTCATGGCATCGGAGACTTATTATTAATTGAAGTCGCAAAAAGGTTACGTG
GTTGCTTACGTTCAAAGGATGTCGTTGCTCGTCAAGGCGGAGATGAGTTTACAATTCTATTACCAGATATGTACTCAGAA
AAAAGTGCGGCTTTTATAGCTGAACAGATTTTAAATATTTTAAACAAACCATTCTTCATTAAAGATGAAGAACTGTCTAT
TACACCAAGTATCGGAATTGCGATGTACCCTGATTGTGGAACTGATGTAACAGAATTAATGAAAAATGCTGATATGGCTA
TGTATCGCGCGAAAGCAAATGGAAAAAACCGATTTGTTTTCTTCTCAAAAGAAATGAGTATCGCTCAAAATGAGAGTAAC
TTCTTAGAAGGAGAACTTTCAAAAGCATTACAACAAAATGAATTTTTCCTTGAATACCAGCCGCAAGTAAGCACAAAAAC
AAAACAAATTATCGGTTTTGAAGCATTAATTCGTTGGAAGCATCCAAAACTCGGCATCGTATCTCCTGCCCAATTCATTC
CTCTAGCAGAGGAAACTGGATTTATTATTGAACTTGGAAATTGGATTTTACGTACTGCTTGCTTAGAAGCAAAAAGATGG
CATAATCAAGGTTTCTCTCACTTAAAAGTCGGTGTGAATTTATCTGTTGTTCAATTTAACCATGCAGATTTAATCCCAAC
TATTTCAAAGGTTTTAGAAGAAACAGAGTTAAAACCAGAAGCACTAGATATTGAAATTACAGAAAGTATCGCCATTAATC
AAAATCAATCTGTAGTTGCAAAACTAGAACAGCTTCAAAACCTCGGTATTCAAATTTCAATTGATGACTTTGGAACCGGT
TATAGTTCTTTAGCTTATTTAACAAAATATCCAATCAACACATTAAAAATTGCTCGAGAATTTATTTGCGGAATTACAAC
TAGCCCTTTAGAGGAAGCGATTATTTCTTCCATTATTACACTATCAAAAGAACTAAATTTAGAGGTTATTGCAGAAGGTG
TAGAGACCGAAGAACAATGGAAGTTTTTATATGAACAAAACTGTGACCACATTCAAGGATTCTTTATTAGCAAGCCCGTT
TCTAGTAAAGACGTTTGGAGGTTACTCCACAAAAAAACAACCGTCTAA

Upstream 100 bases:

>100_bases
TATTAGAGGACTAGCTCAATTTTCATTCGATAGCATCTTTATCGTTATTATGAATATTTATTTTACCTTAACTTTTATTT
TGGACATTTCAAGCTTTCGT

Downstream 100 bases:

>100_bases
GTAAGACGGTTGTTTTTTTTAATATTCAAAAGGTACATCTGAAGCTAATTGTACTTCTTGATCATTATGAGAAATTACTT
GGTTTTTCTCTAAAGCTGTA

Product: sensory box/GGDEF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 735; Mature: 735

Protein sequence:

>735_residues
MLTTDTWVLIGYFIAQSLVIYAVISLYRREEYSSSRISLIIGFTIILVYGYIHLFQLNAGIKPSSEVSYLIHTASILLIG
LSSILYILDKPIQHETKTKYYRFDYVRFILPYFSIIITFSFIIFQPWDDKFMLIGLVLSLILLFLRQLYMWKDNQALIDT
YEQLTTQLEGKVEEGASALSKSEQRYKSLFEDHPDAVFSLNMYGIFQQSNTACESLFTAYYCEVESYSLLHFIDPKDHDL
LQKALQLTKEGSPQTLEVRTKEKEGYYYYLHITLIPTFINKEVVGMFGIARDITTLYEKQKQVEHLAFHDALTGLPNRRK
FEKDLKNILNTAQASANDVAVMFLDLDRFKKINDRLGHGIGDLLLIEVAKRLRGCLRSKDVVARQGGDEFTILLPDMYSE
KSAAFIAEQILNILNKPFFIKDEELSITPSIGIAMYPDCGTDVTELMKNADMAMYRAKANGKNRFVFFSKEMSIAQNESN
FLEGELSKALQQNEFFLEYQPQVSTKTKQIIGFEALIRWKHPKLGIVSPAQFIPLAEETGFIIELGNWILRTACLEAKRW
HNQGFSHLKVGVNLSVVQFNHADLIPTISKVLEETELKPEALDIEITESIAINQNQSVVAKLEQLQNLGIQISIDDFGTG
YSSLAYLTKYPINTLKIAREFICGITTSPLEEAIISSIITLSKELNLEVIAEGVETEEQWKFLYEQNCDHIQGFFISKPV
SSKDVWRLLHKKTTV

Sequences:

>Translated_735_residues
MLTTDTWVLIGYFIAQSLVIYAVISLYRREEYSSSRISLIIGFTIILVYGYIHLFQLNAGIKPSSEVSYLIHTASILLIG
LSSILYILDKPIQHETKTKYYRFDYVRFILPYFSIIITFSFIIFQPWDDKFMLIGLVLSLILLFLRQLYMWKDNQALIDT
YEQLTTQLEGKVEEGASALSKSEQRYKSLFEDHPDAVFSLNMYGIFQQSNTACESLFTAYYCEVESYSLLHFIDPKDHDL
LQKALQLTKEGSPQTLEVRTKEKEGYYYYLHITLIPTFINKEVVGMFGIARDITTLYEKQKQVEHLAFHDALTGLPNRRK
FEKDLKNILNTAQASANDVAVMFLDLDRFKKINDRLGHGIGDLLLIEVAKRLRGCLRSKDVVARQGGDEFTILLPDMYSE
KSAAFIAEQILNILNKPFFIKDEELSITPSIGIAMYPDCGTDVTELMKNADMAMYRAKANGKNRFVFFSKEMSIAQNESN
FLEGELSKALQQNEFFLEYQPQVSTKTKQIIGFEALIRWKHPKLGIVSPAQFIPLAEETGFIIELGNWILRTACLEAKRW
HNQGFSHLKVGVNLSVVQFNHADLIPTISKVLEETELKPEALDIEITESIAINQNQSVVAKLEQLQNLGIQISIDDFGTG
YSSLAYLTKYPINTLKIAREFICGITTSPLEEAIISSIITLSKELNLEVIAEGVETEEQWKFLYEQNCDHIQGFFISKPV
SSKDVWRLLHKKTTV
>Mature_735_residues
MLTTDTWVLIGYFIAQSLVIYAVISLYRREEYSSSRISLIIGFTIILVYGYIHLFQLNAGIKPSSEVSYLIHTASILLIG
LSSILYILDKPIQHETKTKYYRFDYVRFILPYFSIIITFSFIIFQPWDDKFMLIGLVLSLILLFLRQLYMWKDNQALIDT
YEQLTTQLEGKVEEGASALSKSEQRYKSLFEDHPDAVFSLNMYGIFQQSNTACESLFTAYYCEVESYSLLHFIDPKDHDL
LQKALQLTKEGSPQTLEVRTKEKEGYYYYLHITLIPTFINKEVVGMFGIARDITTLYEKQKQVEHLAFHDALTGLPNRRK
FEKDLKNILNTAQASANDVAVMFLDLDRFKKINDRLGHGIGDLLLIEVAKRLRGCLRSKDVVARQGGDEFTILLPDMYSE
KSAAFIAEQILNILNKPFFIKDEELSITPSIGIAMYPDCGTDVTELMKNADMAMYRAKANGKNRFVFFSKEMSIAQNESN
FLEGELSKALQQNEFFLEYQPQVSTKTKQIIGFEALIRWKHPKLGIVSPAQFIPLAEETGFIIELGNWILRTACLEAKRW
HNQGFSHLKVGVNLSVVQFNHADLIPTISKVLEETELKPEALDIEITESIAINQNQSVVAKLEQLQNLGIQISIDDFGTG
YSSLAYLTKYPINTLKIAREFICGITTSPLEEAIISSIITLSKELNLEVIAEGVETEEQWKFLYEQNCDHIQGFFISKPV
SSKDVWRLLHKKTTV

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=431, Percent_Identity=36.4269141531323, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI87081921, Length=429, Percent_Identity=33.3333333333333, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI226510982, Length=428, Percent_Identity=28.2710280373832, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1788502, Length=250, Percent_Identity=32.8, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788381, Length=461, Percent_Identity=26.4642082429501, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI87081845, Length=259, Percent_Identity=30.8880308880309, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1790496, Length=242, Percent_Identity=33.0578512396694, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI1787055, Length=256, Percent_Identity=33.203125, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081980, Length=240, Percent_Identity=32.0833333333333, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1786507, Length=241, Percent_Identity=29.8755186721992, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788849, Length=433, Percent_Identity=26.5588914549654, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87081881, Length=187, Percent_Identity=39.0374331550802, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=28.9256198347107, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=31.7919075144509, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788956, Length=174, Percent_Identity=39.6551724137931, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI87082096, Length=257, Percent_Identity=29.5719844357977, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI87082007, Length=195, Percent_Identity=34.3589743589744, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI87081977, Length=187, Percent_Identity=33.1550802139037, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787262, Length=177, Percent_Identity=32.2033898305085, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI145693134, Length=175, Percent_Identity=36.5714285714286, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1787816, Length=169, Percent_Identity=32.5443786982249, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=34.3195266272189, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788085, Length=184, Percent_Identity=28.2608695652174, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787410, Length=221, Percent_Identity=26.2443438914027, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1787056, Length=179, Percent_Identity=32.4022346368715, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=32.9032258064516, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 84090; Mature: 84090

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTDTWVLIGYFIAQSLVIYAVISLYRREEYSSSRISLIIGFTIILVYGYIHLFQLNAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCC
IKPSSEVSYLIHTASILLIGLSSILYILDKPIQHETKTKYYRFDYVRFILPYFSIIITFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FIIFQPWDDKFMLIGLVLSLILLFLRQLYMWKDNQALIDTYEQLTTQLEGKVEEGASALS
HHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
KSEQRYKSLFEDHPDAVFSLNMYGIFQQSNTACESLFTAYYCEVESYSLLHFIDPKDHDL
HHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHEEECCCEEEEEECCCCHHH
LQKALQLTKEGSPQTLEVRTKEKEGYYYYLHITLIPTFINKEVVGMFGIARDITTLYEKQ
HHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEEEHHHCHHHHHHHHHHHHHHHHHHHH
KQVEHLAFHDALTGLPNRRKFEKDLKNILNTAQASANDVAVMFLDLDRFKKINDRLGHGI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHCCCH
GDLLLIEVAKRLRGCLRSKDVVARQGGDEFTILLPDMYSEKSAAFIAEQILNILNKPFFI
HHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEE
KDEELSITPSIGIAMYPDCGTDVTELMKNADMAMYRAKANGKNRFVFFSKEMSIAQNESN
ECCCEEECCCCCEEECCCCCCCHHHHHHCCCHHEEEECCCCCCEEEEEECCCHHHCCCCH
FLEGELSKALQQNEFFLEYQPQVSTKTKQIIGFEALIRWKHPKLGIVSPAQFIPLAEETG
HHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHEECCCCCCCCCCHHHCCCCCCCC
FIIELGNWILRTACLEAKRWHNQGFSHLKVGVNLSVVQFNHADLIPTISKVLEETELKPE
CEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHHHCCCCC
ALDIEITESIAINQNQSVVAKLEQLQNLGIQISIDDFGTGYSSLAYLTKYPINTLKIARE
EEEEEEECCEEECCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHH
FICGITTSPLEEAIISSIITLSKELNLEVIAEGVETEEQWKFLYEQNCDHIQGFFISKPV
HHHCCCCCHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHCCCCHHCCEEEECCC
SSKDVWRLLHKKTTV
CHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTTDTWVLIGYFIAQSLVIYAVISLYRREEYSSSRISLIIGFTIILVYGYIHLFQLNAG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCC
IKPSSEVSYLIHTASILLIGLSSILYILDKPIQHETKTKYYRFDYVRFILPYFSIIITFS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FIIFQPWDDKFMLIGLVLSLILLFLRQLYMWKDNQALIDTYEQLTTQLEGKVEEGASALS
HHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
KSEQRYKSLFEDHPDAVFSLNMYGIFQQSNTACESLFTAYYCEVESYSLLHFIDPKDHDL
HHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHEEECCCEEEEEECCCCHHH
LQKALQLTKEGSPQTLEVRTKEKEGYYYYLHITLIPTFINKEVVGMFGIARDITTLYEKQ
HHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEEEHHHCHHHHHHHHHHHHHHHHHHHH
KQVEHLAFHDALTGLPNRRKFEKDLKNILNTAQASANDVAVMFLDLDRFKKINDRLGHGI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHCCCH
GDLLLIEVAKRLRGCLRSKDVVARQGGDEFTILLPDMYSEKSAAFIAEQILNILNKPFFI
HHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEE
KDEELSITPSIGIAMYPDCGTDVTELMKNADMAMYRAKANGKNRFVFFSKEMSIAQNESN
ECCCEEECCCCCEEECCCCCCCHHHHHHCCCHHEEEECCCCCCEEEEEECCCHHHCCCCH
FLEGELSKALQQNEFFLEYQPQVSTKTKQIIGFEALIRWKHPKLGIVSPAQFIPLAEETG
HHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHEECCCCCCCCCCHHHCCCCCCCC
FIIELGNWILRTACLEAKRWHNQGFSHLKVGVNLSVVQFNHADLIPTISKVLEETELKPE
CEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHHHCCCCC
ALDIEITESIAINQNQSVVAKLEQLQNLGIQISIDDFGTGYSSLAYLTKYPINTLKIARE
EEEEEEECCEEECCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHH
FICGITTSPLEEAIISSIITLSKELNLEVIAEGVETEEQWKFLYEQNCDHIQGFFISKPV
HHHCCCCCHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHCCCCHHCCEEEECCC
SSKDVWRLLHKKTTV
CHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]