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The map label for this gene is bceR [H]

Identifier: 218906288

GI number: 218906288

Start: 4901468

End: 4902139

Strand: Reverse

Name: bceR [H]

Synonym: BCAH820_5200

Alternate gene names: 218906288

Gene position: 4902139-4901468 (Counterclockwise)

Preceding gene: 218906299

Following gene: 218906287

Centisome position: 92.45

GC content: 31.99

Gene sequence:

>672_bases
ATGAAAGTCTTATTAGTTGAAGATGAACCAACTATTCGTGAAACAGTGGCCGATGAGTTAAGAAAATGGGGATTTGAAGT
ATGGGCAAGTACAAACTTTGAACATATTTTAAACGATTTTTTAGCTCAATCTCCGCAACTTGTTTTACTTGATATTAACC
TTCCTCATTTTGATGGATTTTATTGGTGTAGAAAAATTCGTGAAGTATCGAAAGTACCAATTATTTTCTTATCATCTCGT
GATAATCCTATGGATATGGTAATGGCCATGAATATGGGGGGAGATGATTTTATGCAGAAACCATTTTATACAGATGTTTT
AGTAGCTAAAATTCAAGCTCTTATGAGACGTACATATTCTTATACACAAACGGAAACAAATGTTGTTGAATATGAAGGTG
TCGTATTAAATTTACAGAGCGGGGAAGTAACATATCATAATCAAATATTGGAATTAACAAAAAATGAGTTTAAAATTTTA
CAGATATTAATGCAGAATATAGGATCGATTGTAAGTCGAGATAATATTATGCGTAAACTTTGGGAAAATGAAAGTTTTGT
TGATGATAATACATTAACAGTAAACGTCGCTCGTGTAAGGAAGAAGCTTGCTGAACTTGGAAAAGAGGAATTTATCCATA
CCAAGAAAGGGCAAGGTTATATTATTACATGA

Upstream 100 bases:

>100_bases
ATGGTAATTTTATACCCTAAACCATAGGACAACCTTACAAATTATAATTCAAACCTTACAAACTTGTAAGGTTAAAATAG
TGCTAGGAGGCAAACTTTTT

Downstream 100 bases:

>100_bases
GTATTTTTCGTTACATAAAAGAACGCCGGTATTTTATGCTTCTTTACTTTTTGATTATGTCATTTATTTCTACCATGATT
TATTTAAGCGAGGGATTAAG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKVLLVEDEPTIRETVADELRKWGFEVWASTNFEHILNDFLAQSPQLVLLDINLPHFDGFYWCRKIREVSKVPIIFLSSR
DNPMDMVMAMNMGGDDFMQKPFYTDVLVAKIQALMRRTYSYTQTETNVVEYEGVVLNLQSGEVTYHNQILELTKNEFKIL
QILMQNIGSIVSRDNIMRKLWENESFVDDNTLTVNVARVRKKLAELGKEEFIHTKKGQGYIIT

Sequences:

>Translated_223_residues
MKVLLVEDEPTIRETVADELRKWGFEVWASTNFEHILNDFLAQSPQLVLLDINLPHFDGFYWCRKIREVSKVPIIFLSSR
DNPMDMVMAMNMGGDDFMQKPFYTDVLVAKIQALMRRTYSYTQTETNVVEYEGVVLNLQSGEVTYHNQILELTKNEFKIL
QILMQNIGSIVSRDNIMRKLWENESFVDDNTLTVNVARVRKKLAELGKEEFIHTKKGQGYIIT
>Mature_223_residues
MKVLLVEDEPTIRETVADELRKWGFEVWASTNFEHILNDFLAQSPQLVLLDINLPHFDGFYWCRKIREVSKVPIIFLSSR
DNPMDMVMAMNMGGDDFMQKPFYTDVLVAKIQALMRRTYSYTQTETNVVEYEGVVLNLQSGEVTYHNQILELTKNEFKIL
QILMQNIGSIVSRDNIMRKLWENESFVDDNTLTVNVARVRKKLAELGKEEFIHTKKGQGYIIT

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=31.981981981982, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=27.7272727272727, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=29.5454545454545, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=30.0884955752212, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=28.7671232876712, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=30.9090909090909, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=32.4444444444444, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=28.7610619469027, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=29.0748898678414, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=28.3185840707965, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=28.4444444444444, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=30.6666666666667, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=28.82096069869, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25990; Mature: 25990

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLLVEDEPTIRETVADELRKWGFEVWASTNFEHILNDFLAQSPQLVLLDINLPHFDGF
CEEEEECCCCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHH
YWCRKIREVSKVPIIFLSSRDNPMDMVMAMNMGGDDFMQKPFYTDVLVAKIQALMRRTYS
HHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
YTQTETNVVEYEGVVLNLQSGEVTYHNQILELTKNEFKILQILMQNIGSIVSRDNIMRKL
HCCCCCCEEEECCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WENESFVDDNTLTVNVARVRKKLAELGKEEFIHTKKGQGYIIT
HCCCCCCCCCEEEEEHHHHHHHHHHHCHHHHHCCCCCCEEEEC
>Mature Secondary Structure
MKVLLVEDEPTIRETVADELRKWGFEVWASTNFEHILNDFLAQSPQLVLLDINLPHFDGF
CEEEEECCCCHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHH
YWCRKIREVSKVPIIFLSSRDNPMDMVMAMNMGGDDFMQKPFYTDVLVAKIQALMRRTYS
HHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
YTQTETNVVEYEGVVLNLQSGEVTYHNQILELTKNEFKILQILMQNIGSIVSRDNIMRKL
HCCCCCCEEEECCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WENESFVDDNTLTVNVARVRKKLAELGKEEFIHTKKGQGYIIT
HCCCCCCCCCEEEEEHHHHHHHHHHHCHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]