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The map label for this gene is sigM [H]

Identifier: 218905848

GI number: 218905848

Start: 4488283

End: 4488792

Strand: Reverse

Name: sigM [H]

Synonym: BCAH820_4736

Alternate gene names: 218905848

Gene position: 4488792-4488283 (Counterclockwise)

Preceding gene: 218905849

Following gene: 218905847

Centisome position: 84.65

GC content: 34.31

Gene sequence:

>510_bases
ATGAGCCATGATACATTTGAATCGTTATTAATAGAGAAGTCAAAAGCTGTGTTTGGATACTTAATTAAGATTGGAGCAAA
TAGAAAAGAAGCAGAAGATATTGTACAAGATACGTTGTATAAAGCTTTATTGCTTATGGAGGAAATACCGTTAGAACATT
TAACACCGTGGCTCTTTAGAGTTGCGATCAATCAGCACCGAGATTTACACCGAAAAGAAAAAAGACTAAATCCAATTGCG
ATTGAATCTGTCGTTCTTATTGGTCAAAAGTCATTAGATGAAGTGCTTTTAACAAGTGAACTACAAGGCGAGGTACAAGA
AATATTGGAGACGATGACGGAGGAATATCGCTATATTTTACTGTTGAAATATGAATATGAACTGTCTTATAAGGAAATTG
CCATTTTATTAAATATGAAAGAAGAAACAGTGAAAACAAGTTTGTACCGTGCAAGAAATCAATTTAAAAAATTGTACAGG
AGGAGAAACGATGGGGCGGAAGGACTTTGA

Upstream 100 bases:

>100_bases
CACATCAAAATGGATGTGCTTTTTATTATTAAAATTTTTTTAAGAAAAGCTGTATACATTTTACGCTCTCAAACGTTGAG
TATATAGAAAGGAGAGCTAG

Downstream 100 bases:

>100_bases
TTTGAATATGGATGATAAGCAGATGAAGACTTTGATGAAGAAGGCGAAGAGGAAGCAGTTTTGGAGAAATCTAGTAATCT
CAGTAGTTGTGACATTAGTC

Product: RNA polymerase sigma-70 factor, ECF subfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFRVAINQHRDLHRKEKRLNPIA
IESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRYILLLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYR
RRNDGAEGL

Sequences:

>Translated_169_residues
MSHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFRVAINQHRDLHRKEKRLNPIA
IESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRYILLLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYR
RRNDGAEGL
>Mature_168_residues
SHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFRVAINQHRDLHRKEKRLNPIAI
ESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRYILLLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYRR
RNDGAEGL

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt, acid and e

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014296
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 19930; Mature: 19799

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VAINQHRDLHRKEKRLNPIAIESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRYIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYRRRNDGAEGL
EEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SHDTFESLLIEKSKAVFGYLIKIGANRKEAEDIVQDTLYKALLLMEEIPLEHLTPWLFR
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VAINQHRDLHRKEKRLNPIAIESVVLIGQKSLDEVLLTSELQGEVQEILETMTEEYRYIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
LLKYEYELSYKEIAILLNMKEETVKTSLYRARNQFKKLYRRRNDGAEGL
EEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 12775685; 10216858 [H]