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The map label for this gene is coaE [H]

Identifier: 218905811

GI number: 218905811

Start: 4451826

End: 4452428

Strand: Reverse

Name: coaE [H]

Synonym: BCAH820_4699

Alternate gene names: 218905811

Gene position: 4452428-4451826 (Counterclockwise)

Preceding gene: 218905812

Following gene: 218905810

Centisome position: 83.97

GC content: 35.32

Gene sequence:

>603_bases
ATGACGGTAGTAATTGGATTAACGGGAGGTATTGCAAGCGGAAAAAGTACAGTATCTCAAATGTTTCGCGAGCTCAGTAT
ACCAGTTATTGATGCAGATATTATTGCAAGAGAAGTTGTAGAAAAAGGAAAACCAGCATATAACAAAATTGTAGAAGTGT
TTGGAACGGAAGTACTACAAGAAGATGGAGAACTGGATCGACCGAAATTAGGAAGTGTCGTTTTCTATAATGAAGAGAAA
CGATTGCAGTTAAACAAAATTGTTCATCCTGCAGTGCGTGAGGAAATGAATAAGCAAAAGGAAATGTACATAAAAGAAGG
TATGCAAGCGGTTGTGTTAGATATTCCTCTCTTATTTGAAAGTAAATTAACAAGTCTCGTTGACCGCGTTTTAGTTGTAG
CAGTTAAGCCACATACGCAATTAGAACGTTTAATGAAGCGAAATAATTTTTCAGAAGAAGAAGCAACAGCTCGTATTCAA
TCTCAAATGCCGTTAGAAGAAAAAGTGAAAAATGCAGATGAAGTGATAAATAATGATGGCATAATTATGGGAACGAAAAC
ACAATTACAGGCGATTTTAAAGAAATGGAACATTATTGACTAA

Upstream 100 bases:

>100_bases
ATTCCTGCCTGGGGTATTACTCATTATTATTGGAATTTGGAAAATGTAAGTACGGGCGTGGAACATTAGTTTCGCGCCTT
TTATTATGAGGAGGGTTATG

Downstream 100 bases:

>100_bases
AAAATTGTGAAATTAATGAAAATGCTTAGTGACATATCCCCTTTTTGTGTTATACTATTATTGGGATTGGAGATAAATAG
TATAACGCATTCAAGGGGGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTVVIGLTGGIASGKSTVSQMFRELSIPVIDADIIAREVVEKGKPAYNKIVEVFGTEVLQEDGELDRPKLGSVVFYNEEK
RLQLNKIVHPAVREEMNKQKEMYIKEGMQAVVLDIPLLFESKLTSLVDRVLVVAVKPHTQLERLMKRNNFSEEEATARIQ
SQMPLEEKVKNADEVINNDGIIMGTKTQLQAILKKWNIID

Sequences:

>Translated_200_residues
MTVVIGLTGGIASGKSTVSQMFRELSIPVIDADIIAREVVEKGKPAYNKIVEVFGTEVLQEDGELDRPKLGSVVFYNEEK
RLQLNKIVHPAVREEMNKQKEMYIKEGMQAVVLDIPLLFESKLTSLVDRVLVVAVKPHTQLERLMKRNNFSEEEATARIQ
SQMPLEEKVKNADEVINNDGIIMGTKTQLQAILKKWNIID
>Mature_199_residues
TVVIGLTGGIASGKSTVSQMFRELSIPVIDADIIAREVVEKGKPAYNKIVEVFGTEVLQEDGELDRPKLGSVVFYNEEKR
LQLNKIVHPAVREEMNKQKEMYIKEGMQAVVLDIPLLFESKLTSLVDRVLVVAVKPHTQLERLMKRNNFSEEEATARIQS
QMPLEEKVKNADEVINNDGIIMGTKTQLQAILKKWNIID

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=187, Percent_Identity=48.1283422459893, Blast_Score=179, Evalue=1e-45,
Organism=Homo sapiens, GI191252795, Length=187, Percent_Identity=48.1283422459893, Blast_Score=179, Evalue=1e-45,
Organism=Homo sapiens, GI110227607, Length=180, Percent_Identity=37.2222222222222, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI110227605, Length=180, Percent_Identity=37.2222222222222, Blast_Score=107, Evalue=5e-24,
Organism=Homo sapiens, GI110227603, Length=180, Percent_Identity=37.2222222222222, Blast_Score=107, Evalue=5e-24,
Organism=Homo sapiens, GI110227601, Length=180, Percent_Identity=37.2222222222222, Blast_Score=107, Evalue=5e-24,
Organism=Homo sapiens, GI205277394, Length=180, Percent_Identity=37.2222222222222, Blast_Score=107, Evalue=5e-24,
Organism=Escherichia coli, GI1786292, Length=180, Percent_Identity=42.2222222222222, Blast_Score=132, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17554944, Length=182, Percent_Identity=45.0549450549451, Blast_Score=158, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25143409, Length=171, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=198, Percent_Identity=43.9393939393939, Blast_Score=159, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24644728, Length=178, Percent_Identity=45.5056179775281, Blast_Score=163, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24658602, Length=177, Percent_Identity=34.4632768361582, Blast_Score=108, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22561; Mature: 22429

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVVIGLTGGIASGKSTVSQMFRELSIPVIDADIIAREVVEKGKPAYNKIVEVFGTEVLQ
CEEEEEECCCCCCCHHHHHHHHHHHCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EDGELDRPKLGSVVFYNEEKRLQLNKIVHPAVREEMNKQKEMYIKEGMQAVVLDIPLLFE
CCCCCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
SKLTSLVDRVLVVAVKPHTQLERLMKRNNFSEEEATARIQSQMPLEEKVKNADEVINNDG
HHHHHHHHHHHHHEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
IIMGTKTQLQAILKKWNIID
EEEECHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TVVIGLTGGIASGKSTVSQMFRELSIPVIDADIIAREVVEKGKPAYNKIVEVFGTEVLQ
EEEEEECCCCCCCHHHHHHHHHHHCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EDGELDRPKLGSVVFYNEEKRLQLNKIVHPAVREEMNKQKEMYIKEGMQAVVLDIPLLFE
CCCCCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
SKLTSLVDRVLVVAVKPHTQLERLMKRNNFSEEEATARIQSQMPLEEKVKNADEVINNDG
HHHHHHHHHHHHHEECCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
IIMGTKTQLQAILKKWNIID
EEEECHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]