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The map label for this gene is gap1 [H]

Identifier: 218905810

GI number: 218905810

Start: 4450688

End: 4451716

Strand: Reverse

Name: gap1 [H]

Synonym: BCAH820_4698

Alternate gene names: 218905810

Gene position: 4451716-4450688 (Counterclockwise)

Preceding gene: 218905811

Following gene: 218905809

Centisome position: 83.95

GC content: 37.26

Gene sequence:

>1029_bases
ATGACTCGTGTGGCAATTAATGGATTTGGACGTATTGGGAGAATGGTATTTCGTCAGGCAATAAAAGAAAGCGCATTCGA
AATTGTAGCAATCAATGCAAGCTATCCATCTGAAACGTTAGCACATTTAATTAAATATGATACAGTTCACGGTAAGTTTG
ACGGAACAGTAGAAGCATTTGAAGATCACTTATTAGTTGATGGGAAAATGATTCGCCTTTTAAACAACCGCGATCCAAAG
GAATTGCCTTGGACAGATTTAGGTGTTGAAGTTGTAATTGAAGCAACTGGTAAATTTAATTTAAAAGAAAAAGCAAWTCT
TCACGTTGAAGCTGGAGCGAAAAAAGTTATTTTAACAGCGCCTGGTAAAAATGAAGATGTAACAATTGTAGTTGGTGTGA
ACGAAGACCAATTAGATATTACAAAACATACTGTTATTTCAAATGCATCTTGTACAACAAACTGTTTAGCGCCTGTTGTG
AAGGTGTTAGATGAGCAGTTTGGAATTGAAAACGGTTTAATGACGACAGTTCACGCTTATACAAATGACCAAAAAAATAT
TGATAACCCACATAAAGATTTAAGAAGAGCACGTGCTTGCGGACAATCAATTATTCCGACAACGACAGGTGCTGCGAAAG
CGCTAGCAAAAGTTCTTCCGCATTTAAATGGAAAACTTCACGGTATGGCACTTCGTGTACCAACACCAAACGTGTCTCTT
GTTGACTTAGTAGTAGATGTAAAACGTGATGTGACAGTTGAAGCTATTAATGATGCATTCAAAACTGTTGCAAACGGTGC
GTTAAAAGGCATTGTAGAATTCAGCGAAGAGCCTTTAGTATCTATTGACTTTAATACAAATACACACTCAGCTATCATTG
ATGGTTTATCTACAATGGTAATGGGTGATCGTAAAGTGAAAGTGCTTGCTTGGTATGATAACGAGTGGGGCTACTCTCGT
CGTGTTGTAGATCTTGTAACGTTAGTTGTTGACGAATTAGCGAAGCAAGAAAATGTGCAACATATTTAA

Upstream 100 bases:

>100_bases
AAATTAATGAAAATGCTTAGTGACATATCCCCTTTTTGTGTTATACTATTATTGGGATTGGAGATAAATAGTATAACGCA
TTCAAGGGGGATAACATATT

Downstream 100 bases:

>100_bases
GTGAATAAGGGAGAGGGCAAGTGGAATATTTGCCCTCTTTTTTTTATTTTTTTCTGAAAAGGAAAAAAATTATAGGAGTA
TATTTTTGAAAGTGGACATA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTRVAINGFGRIGRMVFRQAIKESAFEIVAINASYPSETLAHLIKYDTVHGKFDGTVEAFEDHLLVDGKMIRLLNNRDPK
ELPWTDLGVEVVIEATGKFNLKEKAXLHVEAGAKKVILTAPGKNEDVTIVVGVNEDQLDITKHTVISNASCTTNCLAPVV
KVLDEQFGIENGLMTTVHAYTNDQKNIDNPHKDLRRARACGQSIIPTTTGAAKALAKVLPHLNGKLHGMALRVPTPNVSL
VDLVVDVKRDVTVEAINDAFKTVANGALKGIVEFSEEPLVSIDFNTNTHSAIIDGLSTMVMGDRKVKVLAWYDNEWGYSR
RVVDLVTLVVDELAKQENVQHI

Sequences:

>Translated_342_residues
MTRVAINGFGRIGRMVFRQAIKESAFEIVAINASYPSETLAHLIKYDTVHGKFDGTVEAFEDHLLVDGKMIRLLNNRDPK
ELPWTDLGVEVVIEATGKFNLKEKAXLHVEAGAKKVILTAPGKNEDVTIVVGVNEDQLDITKHTVISNASCTTNCLAPVV
KVLDEQFGIENGLMTTVHAYTNDQKNIDNPHKDLRRARACGQSIIPTTTGAAKALAKVLPHLNGKLHGMALRVPTPNVSL
VDLVVDVKRDVTVEAINDAFKTVANGALKGIVEFSEEPLVSIDFNTNTHSAIIDGLSTMVMGDRKVKVLAWYDNEWGYSR
RVVDLVTLVVDELAKQENVQHI
>Mature_341_residues
TRVAINGFGRIGRMVFRQAIKESAFEIVAINASYPSETLAHLIKYDTVHGKFDGTVEAFEDHLLVDGKMIRLLNNRDPKE
LPWTDLGVEVVIEATGKFNLKEKAXLHVEAGAKKVILTAPGKNEDVTIVVGVNEDQLDITKHTVISNASCTTNCLAPVVK
VLDEQFGIENGLMTTVHAYTNDQKNIDNPHKDLRRARACGQSIIPTTTGAAKALAKVLPHLNGKLHGMALRVPTPNVSLV
DLVVDVKRDVTVEAINDAFKTVANGALKGIVEFSEEPLVSIDFNTNTHSAIIDGLSTMVMGDRKVKVLAWYDNEWGYSRR
VVDLVTLVVDELAKQENVQHI

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=326, Percent_Identity=47.8527607361963, Blast_Score=311, Evalue=8e-85,
Organism=Homo sapiens, GI7657116, Length=325, Percent_Identity=46.1538461538462, Blast_Score=306, Evalue=2e-83,
Organism=Escherichia coli, GI1788079, Length=325, Percent_Identity=52.3076923076923, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1789295, Length=326, Percent_Identity=47.5460122699387, Blast_Score=317, Evalue=6e-88,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=47.7477477477478, Blast_Score=320, Evalue=7e-88,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=48.048048048048, Blast_Score=320, Evalue=9e-88,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=47.9289940828402, Blast_Score=319, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=48.048048048048, Blast_Score=319, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=48.036253776435, Blast_Score=326, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6321631, Length=328, Percent_Identity=48.4756097560976, Blast_Score=321, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6322468, Length=328, Percent_Identity=48.1707317073171, Blast_Score=320, Evalue=2e-88,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=47.5609756097561, Blast_Score=311, Evalue=6e-85,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=47.5609756097561, Blast_Score=311, Evalue=6e-85,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=47.5609756097561, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=47.5609756097561, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI19922412, Length=341, Percent_Identity=44.574780058651, Blast_Score=289, Evalue=2e-78,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 37478; Mature: 37347

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVAINGFGRIGRMVFRQAIKESAFEIVAINASYPSETLAHLIKYDTVHGKFDGTVEAF
CCEEEECCHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHH
EDHLLVDGKMIRLLNNRDPKELPWTDLGVEVVIEATGKFNLKEKAXLHVEAGAKKVILTA
HCCEEECCHHEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEC
PGKNEDVTIVVGVNEDQLDITKHTVISNASCTTNCLAPVVKVLDEQFGIENGLMTTVHAY
CCCCCCEEEEEECCCCCEEHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
TNDQKNIDNPHKDLRRARACGQSIIPTTTGAAKALAKVLPHLNGKLHGMALRVPTPNVSL
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCH
VDLVVDVKRDVTVEAINDAFKTVANGALKGIVEFSEEPLVSIDFNTNTHSAIIDGLSTMV
HHEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHH
MGDRKVKVLAWYDNEWGYSRRVVDLVTLVVDELAKQENVQHI
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TRVAINGFGRIGRMVFRQAIKESAFEIVAINASYPSETLAHLIKYDTVHGKFDGTVEAF
CEEEECCHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHH
EDHLLVDGKMIRLLNNRDPKELPWTDLGVEVVIEATGKFNLKEKAXLHVEAGAKKVILTA
HCCEEECCHHEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEEC
PGKNEDVTIVVGVNEDQLDITKHTVISNASCTTNCLAPVVKVLDEQFGIENGLMTTVHAY
CCCCCCEEEEEECCCCCEEHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
TNDQKNIDNPHKDLRRARACGQSIIPTTTGAAKALAKVLPHLNGKLHGMALRVPTPNVSL
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCH
VDLVVDVKRDVTVEAINDAFKTVANGALKGIVEFSEEPLVSIDFNTNTHSAIIDGLSTMV
HHEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHH
MGDRKVKVLAWYDNEWGYSRRVVDLVTLVVDELAKQENVQHI
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]